ASHITABA

OTHER NAME(S):

Angelica, Angelica keiskei, Ashitaba du Japon, Herbe de la Longévité, Japanese Ashitaba, Kenso, Leaves of Tomorrow, Sinsuncho, Tomorrow Leaf.

Overview

Overview Information

Ashitaba is a large herb that grows primarily in the central region of Japan. Its root, leaf, and stem are used to make medicine.

Ashitaba is used for persistent heartburn, stomach ulcers, high blood pressure, constipation, and many other conditions, but there is no good scientific evidence to support these uses.

The fresh leaves and dried powder are used as food and in beverages.

How does it work?

There is not enough information to know how ashitaba might work. Some chemicals in ashitaba seem to work as antioxidants. Other chemicals might block secretions of stomach acid. But most research has been done on animals or in test tubes, not people.

Uses

Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of ashitaba for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Ashitaba is POSSIBLY SAFE when taken by mouth at a dose of up to 1000 mg daily, short-term. There isn't enough reliable information available to know if ashitaba is safe or what the side effects might be when taken for longer than 3 months.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if ashitaba is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for ASHITABA Interactions.

Dosing

Dosing

The appropriate dose of ashitaba depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for ashitaba. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Inamori Y, Baba K, Tsujibo H, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo) 1991;39:1604-5. View abstract.
  • Kang MH, Park YK, Kim HY, Kim TS. Green vegetable drink consumption protects peripheral lymphocytes DNA damage in Korean smokers. Biofactors 2004;22:245-7. View abstract.
  • Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231-44. View abstract.
  • Maronpot RR. Toxicological assessment of Ashitaba Chalcone. Food Chem Toxicol. 2015;77:111-9. View abstract.
  • Murakami S, Kijima H, Isobe Y, et al. Inhibition of gastric H+, K(+)-ATPase by chalcone derivatives, xanthoangelol and 4-hydroxyderricin, from Angelica keiskei Koidzumi. J Pharm Pharmacol 1990;42:723-6. View abstract.
  • Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72. View abstract.
  • Ogawa H, Nakashima S, Baba K. Effects of dietary Angelica keiskei on lipid metabolism in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 2003;30:284-8. View abstract.
  • Ogawa H, Ohno M, Baba K. Hypotensive and lipid regulatory actions of 4-hydroxyderricin, a chalcone from Angelica keiskei, in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 2005;32:19-23. View abstract.
  • Sugii M, Ohkita M, Taniguchi M, et al. Xanthoangelol D isolated from the roots of Angelica keiskei inhibits endothelin-1 production through the suppression of nuclear factor-kappaB. Biol Pharm Bull 2005;28:607-10. View abstract.
  • Tabata K, Motani K, Takayanagi N, et al. Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. Biol Pharm Bull 2005;28:1404-7. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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