REHMANNIA

OTHER NAME(S):

Chinese Foxglove, Chinese Rehmanniae Radix, Chinese RR, Di Huang, Dihuang, Gun-Ji-Whang, Japanese Rehmanniae Radix, Japanese RR, Jio, Juku-Jio, Kan-Jio, R. Glutinosa, Racine de Rehmannia, Radix Rehmanniae, Rehmanniae, Rehmannia Glutinosa Oligosaccharide, Rehmannia glutinosa, Rehmannia Radac, Rehmanniae Radix, Rehmanniae Root, RR, Rhemannia Root, Rehmannia Steamed Root, RGAE, RGX, ROS, Saeng-Ji-Whang, Sheng Dihuang, Sho-Jio, Shu Di Huang, Shu Dihuang, Sook-Ji-Whang, To-Byun, Xian Dihuang.<br/><br/>

Overview

Overview Information

Rehmannia is a plant. The roots of the plant are used to make medicine. Rehmannia is commonly found in herbal combinations used in Traditional Chinese Medicine.

Rehmannia is used for diabetes, metabolic syndrome, obesity, kidney disease, chronic obstructive pulmonary disease (COPD), "tired blood" (anemia), fever, weakened bones (osteoporosis), rheumatoid arthritis (RA), and allergies.

How does it work?

There is not enough information to know how rehmannia might work for any medical condition. However, some chemicals in rehmannia seem to affect the immune system and nervous system. Rehmannia might also reduce pain and swelling. Some chemicals in rehmannia seem to lower blood sugar levels.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Anemia caused by bone marrow failure (aplastic anemia). Early research shows that taking rehmannia along with the drug stanozolol helps to improve symptoms of aplastic anemia better than stanozolol alone.
  • Kidney disease. Early research shows that taking rehmannia along with the drug irbesartan decreases the amount of protein in the urine better than irbesartan alone in people with long-standing inflammation of the kidneys (chronic glomerulonephritis)
  • Obesity. Early research shows that taking steamed rehmannia root extract decreases waist size in women who are obese. However, rehmannia does not seem to decrease body weight or body fat.
  • Diabetes.
  • Metabolic syndrome.
  • Fever.
  • "Weakened bones" (osteoporosis).
  • Allergies.
  • Chronic obstructive pulmonary disease (COPD).
  • As a general tonic.
  • Other conditions.
More evidence is needed to rate the effectiveness of rehmannia for these uses.

Side Effects

Side Effects & Safety

Rehmannia is POSSIBLY SAFE when taken by mouth for 8 weeks or less. There is not enough information available to know if rehmannia is safe to take for longer than 8 weeks.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking rehmannia if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Diabetes: Since rehmannia might affect blood sugar levels, people with diabetes should avoid or be very cautious about taking rehmannia. If you have diabetes and take rehmannia, monitor your blood sugar carefully.

Surgery: Because rehmannia might affect blood glucose levels, it might interfere with blood sugar control during and after surgery. Stop using rehmannia at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Medications for diabetes (Antidiabetes drugs) interacts with REHMANNIA

    Rehmannia might decrease blood sugar. There is concern that taking rehmannia with other medications for diabetes might cause blood sugar to decrease too much. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br /> Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTabs, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Dosing

Dosing

The appropriate dose of rehmannia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for rehmannia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. View abstract.
  • Liang, R., Chen, M. R., and Xu, X. [Effect of dandi tablet on blood lipids and sex hormones in women of postmenopausal stage]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2003;23(8):593-595. View abstract.
  • Liu, J. Q. and Wu, D. W. [32 cases of postoperative osteogenic sarcoma treated by chemotherapy combined with Chinese medicinal herbs]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1993;13(3):150-2, 132. View abstract.
  • Su, Z. Z., He, Y. Y., and Chen, G. [Clinical and experimental study on effects of man-shen-ling oral liquid in the treatment of 100 cases of chronic nephritis]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1993;13(5):269-60. View abstract.
  • Yap, H. K., Ang, S. G., Lai, Y. H., Ramgolam, V., and Jordan, S. C. Improvement in lupus nephritis following treatment with a Chinese herbal preparation. Arch Pediatr Adolesc.Med 1999;153(8):850-852. View abstract.
  • Yin, X. J., Liu, D. X., Wang, H. C., and Zhou, Y. A study on the mutagenicity of 102 raw pharmaceuticals used in Chinese traditional medicine. Mutat.Res 1991;260(1):73-82. View abstract.
  • Zee-Cheng, R. K. Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. Methods Find.Exp Clin Pharmacol 1992;14(9):725-736. View abstract.
  • Chen, L. Z., Feng, X. W., and Zhou, J. H. Effects of Rehmannia glutinosa polysaccharide b on T-lymphocytes in mice bearing sarcoma 180. Zhongguo Yao Li Xue.Bao. 1995;16(4):337-340. View abstract.
  • Cui, Z. B., Yuan, Y. D., Liu, S. H., Han, D., Gao, X., and Qi, F. [Intervention effect of tongfei mixture on nocturnal hypoxia in patients with chronic obstructive pulmonary disease]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2004;24(10):885-888. View abstract.
  • Han K, Bose S, Kim YM, et al. Rehmannia glutinosa reduced waist circumferences of Korean obese women possibly through modulation of gut microbiota. Food Funct 2015;6(8):2684-92. View abstract.
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  • Liang S. TCM treatment for 50 cases of acute protrusion of the lumbar intervertebral disc. JTCM 2001;21(4):265-266.
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  • Miura, T., Kako, M., Ishihara, E., Usami, M., Yano, H., Tanigawa, K., Sudo, K., and Seino, Y. Antidiabetic effect of seishin-kanro-to in KK-Ay mice. Planta Med 1997;63(4):320-322. View abstract.
  • Nishimura H, Yamaguchi T, Sasaki H, and et al. Enzyme inhibitory activities of phenethyl alcohol glycosides from Rehmannia glutinosa [poster]. Planta Med 1990;56:684.
  • Oh KO, Kim SW, et al. Effect of Rehmannia glutinosa Libosch extracts on bone metabolism. Clin Chim Acta 2003;334:185-95. View abstract.
  • Qiu H, Fu P, Fan W, et al. Treatment of primary chronic glomerulonephritis with Rehmannia glutinosa acteosides in combination with angiotensin receptor blocker irbestartan: a randomized controlled trial. Phytother Res 2014;28(1):132-6. View abstract.
  • Sasaki H, Nishimura H, Morota T, et al. Immunosuppressive principles of Rehmannia glutinosa var. hueichingensis. Planta Med 1989;55:458-62. View abstract.
  • Teng L, Hong F, Zhang C, et al. Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease. Neural Regan Res 2014;9(4):407-12. View abstract.
  • Wei, X. L. and Ru, X. B. [Effects of low-molecular-weight Rehmannia glutinosa polysaccharides on p53 gene expression]. Zhongguo Yao Li Xue.Bao. 1997;18(5):471-474. View abstract.
  • Wu B, Liu P, Gao Y, Wang Y. Effect of water extract from traditional Chinese medicines Rehmannia glutinosa, Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat. Zhongguo Zhong Yao Za Zhi 2011;36(19):2710-4. View abstract.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.