Overview

Evodia (Evodia rutaecarpa) is a tree native to China and Korea. The fruit has a bitter taste and is commonly used in Traditional Chinese Medicine (TCM).

Chemicals in evodia might have many effects in the body, such as reducing pain, swelling, diarrhea, and blood pressure, and stimulating the heart.

People use evodia for diarrhea, vomiting, stomach pain, and many other conditions, but there is no good scientific evidence to support these uses.

Uses & Effectiveness ?

We currently have no information for EVODIA overview.

Side Effects

When taken by mouth: There isn't enough reliable information to know if evodia is safe or what the side effects might be.

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if evodia is safe or what the side effects might be. Pregnancy: Evodia is possibly unsafe to use while pregnant. It contains some chemicals that affect pregnant animals. These chemicals cause the animals' uterus to contract and also seem to reduce the size of the litter. It's not known if evodia affects pregnancy in humans, but it's best to stay on the safe side and avoid use.

Breast-feeding: There isn't enough reliable information to know if evodia is safe to use when breast-feeding. Stay on the safe side and avoid use.

Irregular heartbeat: Evodia might make an irregular heartbeat worse. Don't use evodia if you have this condition.

Surgery: Evodia seems to slow blood clotting. This might increase the risk of bleeding during and after surgery. Stop using evodia at least 2 weeks before a scheduled surgery.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Caffeine interacts with EVODIA

    The body breaks down caffeine to get rid of it. Evodia might increase how quickly the body gets rid of caffeine. Taking evodia along with caffeine might decrease the effects of caffeine.

  • Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with EVODIA

    Some medications are changed and broken down by the liver. Evodia might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with EVODIA

    Some medications are changed and broken down by the liver. Evodia might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Medications that decrease break down of other medications by the liver (Cytochrome P450 CYP1A2 (CYP1A2) inhibitors) interacts with EVODIA

    Evodia is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down evodia. This could change the effects and side effects of evodia.

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with EVODIA

    Evodia might slow blood clotting. Taking evodia along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

  • Theophylline interacts with EVODIA

    Evodia might increase how quickly the body gets rid of theophylline. Taking evodia along with theophylline might decrease the effects of theophylline.

  • Medications that can cause an irregular heartbeat (QT interval-prolonging drugs) interacts with EVODIA

    Evodia might affect electrical currents in the heart. This can increase the risk of having an irregular heartbeat. Some medications can have this same effect. Taking evodia with these medications might increase the risk for a serious heart issue.

  • Chlorzoxazone (Parafon Forte, Paraflex) interacts with EVODIA

    The body breaks down chlorzoxazone to get rid of it. Evodia might increase how quickly the body gets rid of chlorzoxazone. Taking evodia along with chlorzoxazone might decrease the effects of chlorzoxazone.

  • Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates) interacts with EVODIA

    Some medications are changed and broken down by the liver. Evodia might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Medications that decrease break down of other medications in the liver (Cytochrome P450 3A4 (CYP3A4) inhibitors) interacts with EVODIA

    Evodia is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down evodia. This could change the effects and side effects of evodia.

  • Medications that increase break down of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with EVODIA

    Evodia is changed and broken down by the liver. Some drugs increase how quickly the liver changes and breaks down evodia. This could change the effects and side effects of evodia.

Dosing

There isn't enough reliable information to know what an appropriate dose of evodia might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.