When soy is eaten, certain bacteria in the gut change the chemicals found in soy into equol. But this change only occurs in 20-60% of people. People who are able to convert the chemicals in soy into equol might get more health benefits from soy. These people are called equol producers. Equol supplements can be used as a source of equol for people who are not equol producers.
People use equol for symptoms of menopause. It is also used for aging skin, diabetes, osteoporosis, breast cancer, and many other conditions, but there is no good scientific evidence to support these other uses.
Uses & Effectiveness
Possibly Effective for
Special Precautions and Warnings
Breast Cancer: There isn't enough reliable information about the effects of equol in people with breast cancer, a history of breast cancer, or a family history of breast cancer. Speak with a healthcare professional before taking equol supplements.
Birth control pills (Contraceptive drugs) interacts with EQUOL
Some birth control pills contain estrogen. Taking equol along with birth control pills might increase the risk of side effects from the birth control pills.
Estrogens interacts with EQUOL
Equol might increase the amount of free estrogen in the body. Taking equol along with estrogen might increase the risk of side effects from estrogen replacement therapy.
Testosterone interacts with EQUOL
Equol might increase the amount of free testosterone in the body. Taking equol along with testosterone might increase the risk of side effects from testosterone replacement therapy.
Be cautious with this combination
Water pills (Diuretic Drugs) interacts with EQUOL
Equol can decrease potassium levels. "Water pills" can also decrease potassium levels. Taking equol along with "water pills" might make potassium levels drop too low.
Be watchful with this combination
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.