FERMENTED MILK

OTHER NAME(S):

Arerra, Augat, Bifidobacteria-Fermented Milk (BFM), Buttermilk, Cultured Dairy Foods, Cultured Dairy Products, Cultured Milk Products, Dadhi, Dahi, Ergo, Fermented Dairy Drink, Fermented Dairy Product, Ititu, Matzoon, Mazoni, Ropy Milk, Traditional Fermented Curd.

Overview

Overview Information

Fermented milk products are created when milk ferments with specific kinds of bacteria called Lactobacilli or Bifidobacteria. Fermentation means the milk is partially digested by the bacteria. This makes the milk product easier to digest, especially for people who have milk allergies or are lactose-intolerant. Also, fermentation increases how long the milk product will last on the shelf. Fermented milk is very popular in countries like Japan.

People take fermented milk by mouth for diarrhea caused by a virus or antibiotics, stomach flu, hay fever arthritis, or asthma. It is also used for gastrointestinal disorders, cancer, diabetes, high cholesterol, high blood pressure and many other conditions, but there is no good scientific evidence to support many of these uses.

How does it work?

The special bacteria added to regular milk to make fermented milk breaks down milk proteins and the sugar called lactose. This helps people digest milk better, especially people with allergies to milk protein or people who are lactose intolerant.

Fermented milk also seems to have some antioxidant and immune-stimulating effects.

Uses

Uses & Effectiveness?

Possibly Effective for

  • Hay fever. Some research shows that drinking fermented milk containing Lactobacillus acidophilus reduces runny nose, but not runny or red eyes, in adults with hay fever. Drinking fermented milk containing Lactobacillus casei doesn't reduce runny nose in people allergic to Japanese cedar pollen. Other research shows that drinking fermented milk might decrease the occurrence of hay fever in both children and adolescents. But not all research agrees.
  • Diarrhea in people taking antibiotics (antibiotic-associated diarrhea). Some research shows that taking fermented milk containing Lactobacillus and Bifidobacterium bacteria reduces the risk of developing diarrhea while taking antibiotics. Other research suggests that taking fermented milk containing Lactobacillus reduces the risk of developing diarrhea while taking antibiotics in the hospital.
  • Eczema (atopic dermatitis). Research suggests that drinking fermented milk containing multiple types of bacteria during pregnancy and just after giving birth reduces the chance of a young child developing eczema.
  • Common cold. Some research shows that taking fermented milk made with Lactobacillus casei can help to prevent colds in preschool children. Another type of fermented milk might help to prevent colds in middle-aged men working in an office.
  • Diarrhea. Early research suggests that drinking milk fermented with Lactobacillus casei reduces the severity of diarrhea in infants and children. Other early research shows that using a specific fermented milk product (Actimel) containing multiple types of bacteria reduces the length of time needed to stop diarrhea in children 6 months to 5 years old.
  • A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). Research shows that drinking a fermented milk beverage containing multiple types of bacteria daily for 12-16 weeks improves stomach symptoms caused by H. pylori infection. Other research shows that taking a specific fermented milk product (Actimel) while using antibiotics for H. pylori infections helps the treatment to work faster.
  • High blood pressure. Some research shows that fermented milk lowers systolic (the first number) but not diastolic (the second number) blood pressure in people with high blood pressure.
  • A long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS). Some early research shows that drinking fermented milk twice daily for 4 weeks decreases IBS symptoms, including pain and gas.
  • Inability to properly digest the sugar lactose (lactose intolerance). Some research shows that taking fermented milk containing Lactobacillus casei and Lactobacillus acidophilus reduces bloating, diarrhea, and pain in people with lactose intolerance.
  • Serious illness caused by radiation exposure. Research suggests that drinking fermented milk containing Lactobacillus acidophilus starting 5 days before treatment with radiation reduces diarrhea and other stomach side effects caused by radiation. Drinking fermented milk might also improve stomach discomfort after radiation.
  • Diarrhea caused by rotavirus. Some evidence suggests that drinking a fermented milk product containing Lactobacillus GG for about 5 days reduces how long diarrhea lasts in children with diarrhea caused by rotavirus.

Possibly Ineffective for

  • Asthma. Research shows that taking fermented milk containing Lactobacillus casei, Lactobacillus bulgaricus, and Streptococcus thermophiles every day does not reduce asthma attacks in preschool children. Also, drinking fermented milk during and just after pregnancy does not prevent asthma in the young child.

Insufficient Evidence for

  • Bladder cancer. People who consume more fermented milk products seem to have a lower chance of bladder cancer.
  • Breast cancer. Early research suggests that drinking fermented milk daily for one year is linked to a lower risk of developing breast cancer.
  • Child growth. Early research suggests that giving preschool children a fermented milk beverage containing iron for 101 days improves their nutrition, but does not help with weight or height.
  • Constipation. Early research suggests that drinking fermented milk containing multiple types of bacteria reduces constipation in women. But other research suggests that fermented milk is no better than regular milk.
  • Heart disease. Men who consume more fermented milk products seem to have a lower chance of developing heart disease.
  • Diabetes. Early research suggests that drinking fermented milk does not help to control blood sugar in people with diabetes.
  • High cholesterol. Some research suggests that taking fermented milk while following the American Heart Association (AHA) diet lowers total and low-density lipoprotein (LDL or "bad") cholesterol. But not all research agrees.
  • Long-term swelling (inflammation) in the digestive tract (inflammatory bowel disease or IBD). Early research suggests that taking fermented milk containing lactobacilli and bifidobacteria helps to improves symptoms of IBD.
  • Stomach ulcers. Early research suggests that eating or drinking fermented milk products more often might lower the risk of getting stomach ulcers in adults.
  • A type of inflammatory bowel disease (ulcerative colitis). Early research shows that drinking fermented milk containing certain probiotic bacteria every day helps to decrease symptoms of ulcerative colitis. But drinking fermented milk with other probiotic bacteria doesn't seem to help.
  • Upper airway infection. Early research shows that taking fermented milk does not help to prevent upper airway infections in preschool children or very elderly adults.
  • Arthritis.
  • Crohn disease.
  • Dental cavities.
  • Indigestion.
  • Stomach gas.
  • Gallbladder disease.
  • Stomach cancer.
  • Stomach reflux.
  • Iron deficiency anemia.
  • Heart disease.
  • Obesity.
  • Osteoporosis.
  • Pancreas infection.
  • Tuberculosis.
  • Bladder infections.
  • Canker sores.
  • Sunburn.
  • Skin breakages.
  • Vaginal infections.
  • Wrinkled skin.
  • Other conditions.
More evidence is needed to rate fermented milk for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Fermented milk is LIKELY SAFE when taken in amounts commonly found in foods. Fermented milk is POSSIBLY SAFE when taken in amounts used for medicine for up to one year. Some side effects of fermented milk include stomach pain, diarrhea, and constipation.

When applied to the skin: There isn't enough reliable information to know if fermented milk is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if it is safe to use fermented milk when pregnant or breast-feeding. Stay on the safe side and avoid using in amounts greater than those commonly found in food.

Children: Fermented milk is LIKELY SAFE when taken by mouth in amounts commonly found in foods. Fermented milk is POSSIBLY SAFE when taken by mouth in medicinal amounts for up to 5 days.

Low blood pressure: Fermented milk might reduce blood pressure. In theory, taking fermented milk might cause blood pressure to become too low when used by people who already have low blood pressure.

Weakened immune system: Some fermented milk products contain live bacteria. There is some concern that the bacteria in fermented milk might grow too well in people whose immune systems are weakened. This includes people with HIV/AIDS or people who have taken medicines to prevent rejection of a transplanted organ. Lactobacillus, one type of bacteria found in fermented milk products, has caused disease (rarely) in people with weakened immune systems. To be on the safe side, if you have a weakened immune system, talk with your healthcare provider before taking fermented milk products.

Interactions

Interactions?

We currently have no information for FERMENTED MILK Interactions.

Dosing

Dosing

ADULT

BY MOUTH:

  • For hay fever: 100 mL of heat-treated fermented milk containing Lactobacillus acidophilus daily for 8 weeks has been used.
  • For diarrhea in people taking antibiotics (antibiotic-associated diarrhea): 250 mL of fermented milk containing Lactobacillus rhamnosus, Lactobacillus acidophilus, and Bifidobacterium daily for 14 days has been used. 49 grams of fermented milk containing Lactobacillus acidophilus and Lactobacillus casei (Bio-K+ CL1285, Bio-K+ International Inc) daily for 2 days followed by 98 grams daily until the end of antibiotic treatment has been used.
  • For eczema (atopic dermatitis): 250 mL of fermented milk containing Lactobacillus rhamnosus GG 5 x 1010 colony forming units (CFU), Lactobacillus acidophilus La-5 5 x 109 CFU, and Bifidobacterium Bb-12 5 x 1010 CFU during pregnancy from 36 weeks until 3 months after giving birth has been used.
  • For a digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori): 100 mL of a fermented milk beverage containing Bifidobacterium bifidum and Streptococcus thermophiles daily for 12 weeks has been used. Fermented milk containing Staphylococcus thermophiles and Lactobacillus johnsonii daily for 16 weeks has been used.
  • For high blood pressure: Six tablets containing powdered fermented milk with Lactobacillus helveticus daily for 4 weeks have been used. 100-150 mL fermented milk prepared with Lactococcus lactis or Lactobacillus casei has been used daily for 5-12 weeks.
  • For a long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS): 200 grams of a specific probiotic fermented milk (AB100 Jianneng, Bright Dairy) containing Streptococcus thermophiles, Lactobacillus bulgaricus, Lactobacillus acidophilus, and Bifidobacterium longum, twice daily for 4 weeks has been used. Also, 125 grams of a specific fermented milk product (Activia, Danone) containing Bifidobacterium animalis and yogurt strains twice daily for 6 weeks has been used.
  • For inability to properly digest the sugar lactose (lactose intolerance): A single dose of 480 mL of fermented milk containing Lactobacillus casei and Lactobacillus acidophilus has been used. A single dose of specific fermented milk products (Ofilus or Bulgofilus) has been used.
  • For serious illness caused by radiation exposure: 150 milliliters of fermented milk containing Lactobacillus acidophilus daily for 5 days before radiotherapy and continuing for 10 days after has been used.
CHILDREN

BY MOUTH:
  • For diarrhea caused by rotavirus: 125 grams of a fermented milk product containing Lactobacillus GG twice daily for 5 days has been used.
  • For hay fever: 100 mL of a fermented milk containing Lactobacillus casei, Lactobacillus bulgaricus, and Streptococcus thermophiles once daily for 12 months has been used. Also, 200-400 mL of fermented milk containing Streptococcus thermophiles, Lactobacillus bulgaricus, and Lactobacillus paracasei daily for 30 days has been used.
  • For diarrhea: 125 or 250 grams of milk fermented by yogurt cultures and Lactobacillus casei daily for one month has been used in infants and children. 100 grams of milk fermented with Lactobacillus casei has been use in children 6 to 24 months old.
  • For a digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori): A specific fermented milk product (Actimel) containing Lactobacillus casei, along with standard antibiotic therapy, daily for 14 days has been used.
  • For the common cold: 200 grams daily of a fermented milk product (Actimel, Danone) containing Lactobacillus casei for 3 months has been used.

View References

REFERENCES:

  • Agarwal, K. N. and Bhasin, S. K. Feasibility studies to control acute diarrhoea in children by feeding fermented milk preparations Actimel and Indian Dahi. Eur J Clin Nutr 2002;56 Suppl 4:S56-S59. View abstract.
  • Aihara, K., Kajimoto, O., Hirata, H., Takahashi, R., and Nakamura, Y. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension. J Am Coll Nutr 2005;24(4):257-265. View abstract.
  • Alm, L. Survival rate of Salmonella and Shigella in fermented milk products with and without added human gastric juice: an in vitro study. Prog Food Nutr Sci 1983;7(3-4):19-28. View abstract.
  • Alm, L. The effect of Lactobacillus acidophilus administration upon the survival of Salmonella in randomly selected human carriers. Prog Food Nutr Sci 1983;7(3-4):13-17. View abstract.
  • Anderson JW, Gilliland SE. Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans. J Am Coll Nutr 1999;18:43-50. View abstract.
  • Andersson, H., Bosaeus, I., Ellegard, L., Grahn, E., Tidehag, P., Hallmans, G., Holm, S., and Sandberg, A. S. Effects of low-fat milk and fermented low-fat milk on cholesterol absorption and excretion in ileostomy subjects. Eur J Clin Nutr 1995;49(4):274-281. View abstract.
  • Beausoleil, M., Fortier, N., Guenette, S., L'ecuyer, A., Savoie, M., Franco, M., Lachaine, J., and Weiss, K. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial. Can J Gastroenterol 2007;21(11):732-736. View abstract.
  • Bernard, B. K., Nakamura, Y., Bando, I., and Mennear, J. H. Studies of the toxicological potential of tripeptides (L-valyl-L-prolyl-L-proline and L-isoleucyl-L-prolyI-L-proline): II. Introduction. Int J Toxicol 2005;24 Suppl 4:5-11. View abstract.
  • Bertolami, M. C., Faludi, A. A., and Batlouni, M. Evaluation of the effects of a new fermented milk product (Gaio) on primary hypercholesterolemia. Eur J Clin Nutr 1999;53(2):97-101. View abstract.
  • Bezkorovainy, A. Probiotics: determinants of survival and growth in the gut. Am J Clin Nutr 2001;73(2 Suppl):399S-405S. View abstract.
  • Biffi, A., Coradini, D., Larsen, R., Riva, L., and Di Fronzo G. Antiproliferative effect of fermented milk on the growth of a human breast cancer cell line. Nutr Cancer 1997;28(1):93-99. View abstract.
  • Bouhnik, Y., Flourie, B., Andrieux, C., Bisetti, N., Briet, F., and Rambaud, J. C. Effects of Bifidobacterium sp fermented milk ingested with or without inulin on colonic bifidobacteria and enzymatic activities in healthy humans. Eur J Clin Nutr 1996;50(4):269-273. View abstract.
  • Bouhnik, Y., Pochart, P., Marteau, P., Arlet, G., Goderel, I., and Rambaud, J. C. Fecal recovery in humans of viable Bifidobacterium sp ingested in fermented milk. Gastroenterology 1992;102(3):875-878. View abstract.
  • Branca, F. and Rossi, L. The role of fermented milk in complementary feeding of young children: lessons from transition countries. Eur J Clin Nutr 2002;56 Suppl 4:S16-S20. View abstract.
  • Brunser, O., Gotteland, M., and Cruchet, S. Functional fermented milk products. Nestle Nutr Workshop Ser Pediatr Program 2007;60:235-247. View abstract.
  • Campbell, C. G., Chew, B. P., Luedecke, L. O., and Shultz, T. D. Yogurt consumption does not enhance immune function in healthy premenopausal women. Nutr Cancer 2000;37(1):27-35. View abstract.
  • Carlsson, P. and Bratthall, D. Secretory and serum antibodies against Streptococcus lactis, Streptococcus thermophilus, and Lactobacillus bulgaricus in relation to ingestion of fermented milk products. Acta Odontol Scand 1985;43(3):147-153. View abstract.
  • Charlton, K. E., Steyn, K., Levitt, N. S., Peer, N., Jonathan, D., Gogela, T., Rossouw, K., Gwebushe, N., and Lombard, C. J. A food-based dietary strategy lowers blood pressure in a low socio-economic setting: a randomised study in South Africa. Public Health Nutr 2008;11(12):1397-1406. View abstract.
  • Cobo Sanz, J. M., Mateos, J. A., and Munoz Conejo A. [Effect of Lactobacillus casei on the incidence of infectious conditions in children]. Nutr Hosp 2006;21(4):547-551. View abstract.
  • Code of Federal Regulations Title 21 - Food and Drugs. Chapter I - Food and Drug Administration. Subchapter B - Food for Human Consumption. Part 131 - Milk and Cream. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=131.112.
  • Cross, M. L., Stevenson, L. M., and Gill, H. S. Anti-allergy properties of fermented foods: an important immunoregulatory mechanism of lactic acid bacteria? Int Immunopharmacol 2001;1(5):891-901. View abstract.
  • de Vrese M, Stegelmann A, Richter B, et al. Probiotics--compensation for lactase insufficiency. Am J Clin Nutr 2001;73:421S-9S. View abstract.
  • de Vrese, M. and Schrezenmeir, J. Probiotics, prebiotics, and synbiotics. Adv Biochem Eng Biotechnol 2008;111:1-66. View abstract.
  • Donnet-Hughes, A., Rochat, F., Serrant, P., Aeschlimann, J. M., and Schiffrin, E. J. Modulation of nonspecific mechanisms of defense by lactic acid bacteria: effective dose. J Dairy Sci 1999;82(5):863-869. View abstract.
  • Ebringer, L., Ferencik, M., and Krajcovic, J. Beneficial health effects of milk and fermented dairy products--review. Folia Microbiol (Praha) 2008;53(5):378-394. View abstract.
  • Elmstahl, S., Svensson, U., and Berglund, G. Fermented milk products are associated to ulcer disease. Results from a cross-sectional population study. Eur J Clin Nutr 1998;52(9):668-674. View abstract.
  • Engberink, M. F., Schouten, E. G., Kok, F. J., van Mierlo, L. A., Brouwer, I. A., and Geleijnse, J. M. Lactotripeptides show no effect on human blood pressure: results from a double-blind randomized controlled trial. Hypertension 2008;51(2):399-405. View abstract.
  • Forssen, K. M., Jagerstad, M. I., Wigertz, K., and Witthoft, C. M. Folates and dairy products: a critical update. J Am Coll Nutr 2000;19(2 Suppl):100S-110S. View abstract.
  • Fredricsson, B., Englund, K., Weintraub, L., Olund, A., and Nord, C. E. Bacterial vaginosis is not a simple ecological disorder. Gynecol Obstet Invest 1989;28(3):156-160. View abstract.
  • Fukushima, Y., Miyaguchi, S., Yamano, T., Kaburagi, T., Iino, H., Ushida, K., and Sato, K. Improvement of nutritional status and incidence of infection in hospitalised, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533). Br J Nutr 2007;98(5):969-977. View abstract.
  • Gaon, D., Doweck, Y., Gomez Zavaglia, A., Ruiz Holgado, A., and Oliver, G. [Lactose digestion by milk fermented with Lactobacillus acidophilus and Lactobacillus casei of human origin]. Medicina (B Aires) 1995;55(3):237-242. View abstract.
  • Giovannini, M., Agostoni, C., Riva, E., Salvini, F., Ruscitto, A., Zuccotti, G. V., and Radaelli, G. A randomized prospective double blind controlled trial on effects of long-term consumption of fermented milk containing Lactobacillus casei in pre-school children with allergic asthma and/or rhinitis. Pediatr Res 2007;62(2):215-220. View abstract.
  • Gluck, U. and Gebbers, J. O. Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and beta-hemolytic streptococci). Am J Clin Nutr 2003;77(2):517-520. View abstract.
  • Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. View abstract.
  • Guyonnet, D., Chassany, O., Ducrotte, P., Picard, C., Mouret, M., Mercier, C. H., and Matuchansky, C. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther 2007;26(3):475-486. View abstract.
  • Henriksson, R., Franzen, L., Sandstrom, K., Nordin, A., Arevarn, M., and Grahn, E. Effects of active addition of bacterial cultures in fermented milk to patients with chronic bowel discomfort following irradiation. Support Care Cancer 1995;3(1):81-83. View abstract.
  • Heyman, M. Effect of lactic acid bacteria on diarrheal diseases. J Am Coll Nutr 2000;19(2 Suppl):137S-146S. View abstract.
  • Hitchins AD, McDonough FE. Prophylactic and therapeutic aspects of fermented milk. Am J Clin Nutr 1989;49(4):675-84. View abstract.
  • Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95. View abstract.
  • Ishida, Y., Nakamura, F., Kanzato, H., Sawada, D., Hirata, H., Nishimura, A., Kajimoto, O., and Fujiwara, S. Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study. J Dairy Sci 2005;88(2):527-533. View abstract.
  • Ishikawa H, Akedo I, Umesaki Y, et al. Randomized controlled trial of the effect of bifidobacteria-fermented milk on ulcerative colitis. J Am Coll Nutr 2003;22:56-63. View abstract.
  • Isolauri E, Juntunen M, Rautanen T, et al. A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 1991;88:90-7. View abstract.
  • Jauhiainen, T., Vapaatalo, H., Poussa, T., Kyronpalo, S., Rasmussen, M., and Korpela, R. Lactobacillus helveticus fermented milk lowers blood pressure in hypertensive subjects in 24-h ambulatory blood pressure measurement. Am J Hypertens 2005;18(12 Pt 1):1600-1605. View abstract.
  • Kaila, M., Isolauri, E., Soppi, E., Virtanen, E., Laine, S., and Arvilommi, H. Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain. Pediatr Res 1992;32(2):141-144. View abstract.
  • Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. View abstract.
  • Kato, K., Mizuno, S., Umesaki, Y., Ishii, Y., Sugitani, M., Imaoka, A., Otsuka, M., Hasunuma, O., Kurihara, R., Iwasaki, A., and Arakawa, Y. Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis. Aliment Pharmacol Ther 2004;20(10):1133-1141. View abstract.
  • Kawase, M., Hashimoto, H., Hosoda, M., Morita, H., and Hosono, A. Effect of administration of fermented milk containing whey protein concentrate to rats and healthy men on serum lipids and blood pressure. J Dairy Sci 2000;83(2):255-263. View abstract.
  • Laake, K. O., Bjorneklett, A., Aamodt, G., Aabakken, L., Jacobsen, M., Bakka, A., and Vatn, M. H. Outcome of four weeks' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scand J Gastroenterol 2005;40(1):43-51. View abstract.
  • Laake, K. O., Line, P. D., Grzyb, K., Aamodt, G., Aabakken, L., Roset, A., Hvinden, A. B., Bakka, A., Eide, J., Bjorneklett, A., and Vatn, M. H. Assessment of mucosal inflammation and blood flow in response to four weeks' intervention with probiotics in patients operated with a J-configurated ileal-pouch-anal-anastomosis (IPAA). Scand J Gastroenterol 2004;39(12):1228-1235. View abstract.
  • Lidbeck, A., Nord, C. E., Gustafsson, J. A., and Rafter, J. Lactobacilli, anticarcinogenic activities and human intestinal microflora. Eur J Cancer Prev 1992;1(5):341-353. View abstract.
  • Lund, B., Edlund, C., Barkholt, L., Nord, C. E., Tvede, M., and Poulsen, R. L. Impact on human intestinal microflora of an Enterococcus faecium probiotic and vancomycin. Scand J Infect Dis 2000;32(6):627-632. View abstract.
  • Mahe, S., Marteau, P., Huneau, J. F., Thuillier, F., and Tome, D. Intestinal nitrogen and electrolyte movements following fermented milk ingestion in man. Br J Nutr 1994;71(2):169-180. View abstract.
  • Marcos, A., Warnberg, J., Nova, E., Gomez, S., Alvarez, A., Alvarez, R., Mateos, J. A., and Cobo, J. M. The effect of milk fermented by yogurt cultures plus Lactobacillus casei DN-114001 on the immune response of subjects under academic examination stress. Eur J Nutr 2004;43(6):381-389. View abstract.
  • Marteau, P., Cuillerier, E., Meance, S., Gerhardt, M. F., Myara, A., Bouvier, M., Bouley, C., Tondu, F., Bommelaer, G., and Grimaud, J. C. Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women: a double-blind, randomized, controlled study. Aliment Pharmacol Ther 2002;16(3):587-593. View abstract.
  • Marteau, P., Pochart, P., Bouhnik, Y., Zidi, S., Goderel, I., and Rambaud, J. C. [Survival of Lactobacillus acidophilus and Bifidobacterium sp. in the small intestine following ingestion in fermented milk. A rational basis for the use of probiotics in man]. Gastroenterol Clin Biol 1992;16(1):25-28. View abstract.
  • Marteau, P., Vaerman, J. P., Dehennin, J. P., Bord, S., Brassart, D., Pochart, P., Desjeux, J. F., and Rambaud, J. C. Effects of intrajejunal perfusion and chronic ingestion of Lactobacillus johnsonii strain La1 on serum concentrations and jejunal secretions of immunoglobulins and serum proteins in healthy humans. Gastroenterol Clin Biol 1997;21(4):293-298. View abstract.
  • Marzotto, M., Maffeis, C., Paternoster, T., Ferrario, R., Rizzotti, L., Pellegrino, M., Dellaglio, F., and Torriani, S. Lactobacillus paracasei A survives gastrointestinal passage and affects the fecal microbiota of healthy infants. Res Microbiol 2006;157(9):857-866. View abstract.
  • Miki, K., Urita, Y., Ishikawa, F., Iino, T., Shibahara-Sone, H., Akahoshi, R., Mizusawa, S., Nose, A., Nozaki, D., Hirano, K., Nonaka, C., and Yokokura, T. Effect of Bifidobacterium bifidum fermented milk on Helicobacter pylori and serum pepsinogen levels in humans. J Dairy Sci 2007;90(6):2630-2640. View abstract.
  • Morimoto, K., Takeshita, T., Nanno, M., Tokudome, S., and Nakayama, K. Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers. Prev Med 2005;40(5):589-594. View abstract.
  • Morita, H., He, F., Kawase, M., Kubota, A., Hiramatsu, M., Kurisaki, J., and Salminen, S. Preliminary human study for possible alteration of serum immunoglobulin E production in perennial allergic rhinitis with fermented milk prepared with Lactobacillus gasseri TMC0356. Microbiol Immunol 2006;50(9):701-706. View abstract.
  • Nagao, F., Nakayama, M., Muto, T., and Okumura, K. Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the immune system in healthy human subjects. Biosci Biotechnol Biochem 2000;64(12):2706-2708. View abstract.
  • Narva, M., Karkkainen, M., Poussa, T., Lamberg-Allardt, C., and Korpela, R. Caseinphosphopeptides in milk and fermented milk do not affect calcium metabolism acutely in postmenopausal women. J Am Coll Nutr 2003;22(1):88-93. View abstract.
  • Narva, M., Nevala, R., Poussa, T., and Korpela, R. The effect of Lactobacillus helveticus fermented milk on acute changes in calcium metabolism in postmenopausal women. Eur J Nutr 2004;43(2):61-68. View abstract.
  • Pantoflickova, D., Corthesy-Theulaz, I., Dorta, G., Stolte, M., Isler, P., Rochat, F., Enslen, M., and Blum, A. L. Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis. Aliment Pharmacol Ther 2003;18(8):805-813. View abstract.
  • Parra, D., De Morentin, B. M., Cobo, J. M., Mateos, A., and Martinez, J. A. Monocyte function in healthy middle-aged people receiving fermented milk containing Lactobacillus casei. J Nutr Health Aging 2004;8(4):208-211. View abstract.
  • Parra, M. D., Martinez de Morentin, B. E., Cobo, J. M., Mateos, A., and Martinez, J. A. Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate-defense capacity in healthy middle-aged people. J Physiol Biochem 2004;60(2):85-91. View abstract.
  • Pedone CA, Arnaud CC, Postaire ER, et al. Multicentric study of the effect of milk fermented by Lactobacillus casei on the incidence of diarrhoea. Int J Clin Pract 2000;54:589-71. View abstract.
  • Pedone CA, Bernabeu AO, Postaire ER, et al. The effect of supplementation with milk fermented by Lactobacillus casei (strain DN-114 001) on acute diarrhoea in children attending day care centres. Int J Clin Pract 1999;53:179-84. View abstract.
  • Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  • Puch, F., Samson-Villeger, S., Guyonnet, D., Blachon, J. L., Rawlings, A. V., and Lassel, T. Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. Exp Dermatol 2008;17(8):668-674. View abstract.
  • Radosavljevic, V., Ilic, M., Jankovic, S., and Djokic, M. [Diet in bladder cancer ethiopathogenesis]. Acta Chir Iugosl 2005;52(3):77-82. View abstract.
  • Rao, D. R., Pulusani, S. R., and Chawan, C. B. Role of fermented milk products in milk intolerance and other clinical conditions. Adv Nutr Res 1985;7:203-219. View abstract.
  • Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60. View abstract.
  • Rio, M. E., Zago Beatriz L., Garcia, H., and Winter, L. [The nutritional status change the effectiveness of a dietary supplement of lactic bacteria on the emerging of respiratory tract diseases in children]. Arch Latinoam Nutr 2002;52(1):29-34. View abstract.
  • Sairanen, U., Piirainen, L., Grasten, S., Tompuri, T., Matto, J., Saarela, M., and Korpela, R. The effect of probiotic fermented milk and inulin on the functions and microecology of the intestine. J Dairy Res 2007;74(3):367-373. View abstract.
  • Saito, Y., Hamanaka, Y., Saito, K., Takizawa, S., and Benno, Y. Stability of species composition of fecal bifidobacteria in human subjects during fermented milk administration. Curr Microbiol 2002;44(5):368-373. View abstract.
  • Salminen, E., Elomaa, I., Minkkinen, J., Vapaatalo, H., and Salminen, S. Preservation of intestinal integrity during radiotherapy using live Lactobacillus acidophilus cultures. Clin Radiol 1988;39(4):435-437. View abstract.
  • Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. View abstract.
  • Schiffrin, E. J., Rochat, F., Link-Amster, H., Aeschlimann, J. M., and Donnet-Hughes, A. Immunomodulation of human blood cells following the ingestion of lactic acid bacteria. J Dairy Sci 1995;78(3):491-497. View abstract.
  • Seppo, L., Jauhiainen, T., Poussa, T., and Korpela, R. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 2003;77(2):326-330. View abstract.
  • Silva, M. R., Dias, G., Ferreira, C. L., Franceschini, S. C., and Costa, N. M. Growth of preschool children was improved when fed an iron-fortified fermented milk beverage supplemented with Lactobacillus acidophilus. Nutr Res 2008;28(4):226-232. View abstract.
  • Solis, B., Nova, E., Gomez, S., Samartin, S., Mouane, N., Lemtouni, A., Belaoui, H., and Marcos, A. The effect of fermented milk on interferon production in malnourished children and in anorexia nervosa patients undergoing nutritional care. Eur J Clin Nutr 2002;56 Suppl 4:S27-S33. View abstract.
  • Songisepp, E., Kals, J., Kullisaar, T., Mandar, R., Hutt, P., Zilmer, M., and Mikelsaar, M. Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutr J 2005;4:22. View abstract.
  • Spanhaak, S., Havenaar, R., and Schaafsma, G. The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans. Eur J Clin Nutr 1998;52(12):899-907. View abstract.
  • St-Onge MP, Farnworth ER, Jones PJ. Consumption of fermented and nonfermented dairy products: effects on cholesterol concentrations and metabolism. Am J Clin Nutr 2000;71:674-81. View abstract.
  • Sykora, J., Valeckova, K., Amlerova, J., Siala, K., Dedek, P., Watkins, S., Varvarovska, J., Stozicky, F., Pazdiora, P., and Schwarz, J. Effects of a specially designed fermented milk product containing probiotic Lactobacillus casei DN-114 001 and the eradication of H. pylori in children: a prospective randomized double-blind study. J Clin Gastroenterol 2005;39(8):692-698. View abstract.
  • Takeda, K. and Okumura, K. Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity. J Nutr 2007;137(3 Suppl 2):791S-793S. View abstract.
  • Takeda, K., Suzuki, T., Shimada, S. I., Shida, K., Nanno, M., and Okumura, K. Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota. Clin Exp Immunol 2006;146(1):109-115. View abstract.
  • Tamura, M., Shikina, T., Morihana, T., Hayama, M., Kajimoto, O., Sakamoto, A., Kajimoto, Y., Watanabe, O., Nonaka, C., Shida, K., and Nanno, M. Effects of probiotics on allergic rhinitis induced by Japanese cedar pollen: randomized double-blind, placebo-controlled clinical trial. Int Arch Allergy Immunol 2007;143(1):75-82. View abstract.
  • Taylor, G. R. and Williams, C. M. Effects of probiotics and prebiotics on blood lipids. Br J Nutr 1998;80(4):S225-S230. View abstract.
  • Tidehag, P., Sandberg, A. S., Hallmans, G., Wing, K., Turk, M., Holm, S., and Grahn, E. Effect of milk and fermented milk on iron absorption in ileostomy subjects. Am J Clin Nutr 1995;62(6):1234-1238. View abstract.
  • Tormo Carnicer R., Infante Pina D., Rosello Mayans E., and Bartolome Comas R. [Intake of fermented milk containing Lactobacillus casei DN-114 001 and its effect on gut flora]. An Pediatr (Barc) 2006;65(5):448-453. View abstract.
  • Turchet, P., Laurenzano, M., Auboiron, S., and Antoine, J. M. Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study. J Nutr Health Aging 2003;7(2):75-77. View abstract.
  • Vesa, T. H., Marteau, P., Zidi, S., Briet, F., Pochart, P., and Rambaud, J. C. Digestion and tolerance of lactose from yoghurt and different semi-solid fermented dairy products containing Lactobacillus acidophilus and bifidobacteria in lactose maldigesters--is bacterial lactase important? Eur J Clin Nutr 1996;50(11):730-733. View abstract.
  • Walrand, S., Chiotelli, E., Noirt, F., Mwewa, S., and Lassel, T. Consumption of a functional fermented milk containing collagen hydrolysate improves the concentration of collagen-specific amino acids in plasma. J Agric Food Chem 2008;56(17):7790-7795. View abstract.
  • Wang, M. F., Lin, H. C., Wang, Y. Y., and Hsu, C. H. Treatment of perennial allergic rhinitis with lactic acid bacteria. Pediatr Allergy Immunol 2004;15(2):152-158. View abstract.
  • Wenus, C., Goll, R., Loken, E. B., Biong, A. S., Halvorsen, D. S., and Florholmen, J. Prevention of antibiotic-associated diarrhoea by a fermented probiotic milk drink. Eur J Clin Nutr 2008;62(2):299-301. View abstract.
  • Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. View abstract.
  • Yamamoto, N. and Takano, T. Antihypertensive peptides derived from milk proteins. Nahrung 1999;43(3):159-164. View abstract.
  • Yamano, T., Iino, H., Takada, M., Blum, S., Rochat, F., and Fukushima, Y. Improvement of the human intestinal flora by ingestion of the probiotic strain Lactobacillus johnsonii La1. Br J Nutr 2006;95(2):303-312. View abstract.
  • Yang, Y. X., He, M., Hu, G., Wei, J., Pages, P., Yang, X. H., and Bourdu-Naturel, S. Effect of a fermented milk containing Bifidobacterium lactis DN-173010 on Chinese constipated women. World J Gastroenterol 2008;14(40):6237-6243. View abstract.
  • Zeng, J., Li, Y. Q., Zuo, X. L., Zhen, Y. B., Yang, J., and Liu, C. H. Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2008;28(8):994-1002. View abstract.
  • Agarwal, K. N. and Bhasin, S. K. Feasibility studies to control acute diarrhoea in children by feeding fermented milk preparations Actimel and Indian Dahi. Eur J Clin Nutr 2002;56 Suppl 4:S56-S59. View abstract.
  • Aihara, K., Kajimoto, O., Hirata, H., Takahashi, R., and Nakamura, Y. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension. J Am Coll Nutr 2005;24(4):257-265. View abstract.
  • Alm, L. Survival rate of Salmonella and Shigella in fermented milk products with and without added human gastric juice: an in vitro study. Prog Food Nutr Sci 1983;7(3-4):19-28. View abstract.
  • Alm, L. The effect of Lactobacillus acidophilus administration upon the survival of Salmonella in randomly selected human carriers. Prog Food Nutr Sci 1983;7(3-4):13-17. View abstract.
  • Anderson JW, Gilliland SE. Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans. J Am Coll Nutr 1999;18:43-50. View abstract.
  • Andersson, H., Bosaeus, I., Ellegard, L., Grahn, E., Tidehag, P., Hallmans, G., Holm, S., and Sandberg, A. S. Effects of low-fat milk and fermented low-fat milk on cholesterol absorption and excretion in ileostomy subjects. Eur J Clin Nutr 1995;49(4):274-281. View abstract.
  • Aoyagi Y, Park S, Matsubara S, et al. Habitual intake of fermented milk products containing Lactobacillus casei strain Shirota and a reduced risk of hypertension in older people. Benef Microbes. 2017;8(1):23-29. View abstract.
  • Beausoleil, M., Fortier, N., Guenette, S., L'ecuyer, A., Savoie, M., Franco, M., Lachaine, J., and Weiss, K. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial. Can J Gastroenterol 2007;21(11):732-736. View abstract.
  • Beltrán-Barrientos LM, González-Córdova AF, Hernández-Mendoza A, et al. Randomized double-blind controlled clinical trial of the blood pressure-lowering effect of fermented milk with Lactococcus lactis: A pilot study. J Dairy Sci. 2018;101(4):2819-2825. View abstract.
  • Bermejo LM, López-Plaza B, Santurino C, Cavero-Redondo I, Gómez-Candela C. Milk and Dairy Product Consumption and Bladder Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies. Adv Nutr. 2019;10(suppl_2):S224-S238. View abstract.
  • Bernard, B. K., Nakamura, Y., Bando, I., and Mennear, J. H. Studies of the toxicological potential of tripeptides (L-valyl-L-prolyl-L-proline and L-isoleucyl-L-prolyI-L-proline): II. Introduction. Int J Toxicol 2005;24 Suppl 4:5-11. View abstract.
  • Bertolami, M. C., Faludi, A. A., and Batlouni, M. Evaluation of the effects of a new fermented milk product (Gaio) on primary hypercholesterolemia. Eur J Clin Nutr 1999;53(2):97-101. View abstract.
  • Bezkorovainy, A. Probiotics: determinants of survival and growth in the gut. Am J Clin Nutr 2001;73(2 Suppl):399S-405S. View abstract.
  • Biffi, A., Coradini, D., Larsen, R., Riva, L., and Di Fronzo G. Antiproliferative effect of fermented milk on the growth of a human breast cancer cell line. Nutr Cancer 1997;28(1):93-99. View abstract.
  • Bouhnik, Y., Flourie, B., Andrieux, C., Bisetti, N., Briet, F., and Rambaud, J. C. Effects of Bifidobacterium sp fermented milk ingested with or without inulin on colonic bifidobacteria and enzymatic activities in healthy humans. Eur J Clin Nutr 1996;50(4):269-273. View abstract.
  • Bouhnik, Y., Pochart, P., Marteau, P., Arlet, G., Goderel, I., and Rambaud, J. C. Fecal recovery in humans of viable Bifidobacterium sp ingested in fermented milk. Gastroenterology 1992;102(3):875-878. View abstract.
  • Branca, F. and Rossi, L. The role of fermented milk in complementary feeding of young children: lessons from transition countries. Eur J Clin Nutr 2002;56 Suppl 4:S16-S20. View abstract.
  • Brunser, O., Gotteland, M., and Cruchet, S. Functional fermented milk products. Nestle Nutr Workshop Ser Pediatr Program 2007;60:235-247. View abstract.
  • Carlsson, P. and Bratthall, D. Secretory and serum antibodies against Streptococcus lactis, Streptococcus thermophilus, and Lactobacillus bulgaricus in relation to ingestion of fermented milk products. Acta Odontol Scand 1985;43(3):147-153. View abstract.
  • Charlton, K. E., Steyn, K., Levitt, N. S., Peer, N., Jonathan, D., Gogela, T., Rossouw, K., Gwebushe, N., and Lombard, C. J. A food-based dietary strategy lowers blood pressure in a low socio-economic setting: a randomised study in South Africa. Public Health Nutr 2008;11(12):1397-1406. View abstract.
  • Cobo Sanz, J. M., Mateos, J. A., and Munoz Conejo A. [Effect of Lactobacillus casei on the incidence of infectious conditions in children]. Nutr Hosp 2006;21(4):547-551. View abstract.
  • Code of Federal Regulations Title 21 - Food and Drugs. Chapter I - Food and Drug Administration. Subchapter B - Food for Human Consumption. Part 131 - Milk and Cream. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=131.112.
  • Cross, M. L., Stevenson, L. M., and Gill, H. S. Anti-allergy properties of fermented foods: an important immunoregulatory mechanism of lactic acid bacteria? Int Immunopharmacol 2001;1(5):891-901. View abstract.
  • de Vrese M, Stegelmann A, Richter B, et al. Probiotics--compensation for lactase insufficiency. Am J Clin Nutr 2001;73:421S-9S. View abstract.
  • de Vrese, M. and Schrezenmeir, J. Probiotics, prebiotics, and synbiotics. Adv Biochem Eng Biotechnol 2008;111:1-66. View abstract.
  • Donnet-Hughes, A., Rochat, F., Serrant, P., Aeschlimann, J. M., and Schiffrin, E. J. Modulation of nonspecific mechanisms of defense by lactic acid bacteria: effective dose. J Dairy Sci 1999;82(5):863-869. View abstract.
  • Ebringer, L., Ferencik, M., and Krajcovic, J. Beneficial health effects of milk and fermented dairy products--review. Folia Microbiol (Praha) 2008;53(5):378-394. View abstract.
  • Elmstahl, S., Svensson, U., and Berglund, G. Fermented milk products are associated to ulcer disease. Results from a cross-sectional population study. Eur J Clin Nutr 1998;52(9):668-674. View abstract.
  • Engberink, M. F., Schouten, E. G., Kok, F. J., van Mierlo, L. A., Brouwer, I. A., and Geleijnse, J. M. Lactotripeptides show no effect on human blood pressure: results from a double-blind randomized controlled trial. Hypertension 2008;51(2):399-405. View abstract.
  • Forssen, K. M., Jagerstad, M. I., Wigertz, K., and Witthoft, C. M. Folates and dairy products: a critical update. J Am Coll Nutr 2000;19(2 Suppl):100S-110S. View abstract.
  • Fredricsson, B., Englund, K., Weintraub, L., Olund, A., and Nord, C. E. Bacterial vaginosis is not a simple ecological disorder. Gynecol Obstet Invest 1989;28(3):156-160. View abstract.
  • Fukushima, Y., Miyaguchi, S., Yamano, T., Kaburagi, T., Iino, H., Ushida, K., and Sato, K. Improvement of nutritional status and incidence of infection in hospitalised, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533). Br J Nutr 2007;98(5):969-977. View abstract.
  • Gaon, D., Doweck, Y., Gomez Zavaglia, A., Ruiz Holgado, A., and Oliver, G. [Lactose digestion by milk fermented with Lactobacillus acidophilus and Lactobacillus casei of human origin]. Medicina (B Aires) 1995;55(3):237-242. View abstract.
  • Giovannini, M., Agostoni, C., Riva, E., Salvini, F., Ruscitto, A., Zuccotti, G. V., and Radaelli, G. A randomized prospective double blind controlled trial on effects of long-term consumption of fermented milk containing Lactobacillus casei in pre-school children with allergic asthma and/or rhinitis. Pediatr Res 2007;62(2):215-220. View abstract.
  • Gluck, U. and Gebbers, J. O. Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and beta-hemolytic streptococci). Am J Clin Nutr 2003;77(2):517-520. View abstract.
  • Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. View abstract.
  • Guyonnet, D., Chassany, O., Ducrotte, P., Picard, C., Mouret, M., Mercier, C. H., and Matuchansky, C. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther 2007;26(3):475-486. View abstract.
  • Henriksson, R., Franzen, L., Sandstrom, K., Nordin, A., Arevarn, M., and Grahn, E. Effects of active addition of bacterial cultures in fermented milk to patients with chronic bowel discomfort following irradiation. Support Care Cancer 1995;3(1):81-83. View abstract.
  • Heyman, M. Effect of lactic acid bacteria on diarrheal diseases. J Am Coll Nutr 2000;19(2 Suppl):137S-146S. View abstract.
  • Hitchins AD, McDonough FE. Prophylactic and therapeutic aspects of fermented milk. Am J Clin Nutr 1989;49(4):675-84. View abstract.
  • Hove KD, Brøns C, Færch K, Lund SS, Rossing P, Vaag A. Effects of 12 weeks of treatment with fermented milk on blood pressure, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: a randomised double-blind placebo-controlled study. Eur J Endocrinol. 2015;172(1):11-20. View abstract.
  • Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95. View abstract.
  • Ishida, Y., Nakamura, F., Kanzato, H., Sawada, D., Hirata, H., Nishimura, A., Kajimoto, O., and Fujiwara, S. Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study. J Dairy Sci 2005;88(2):527-533. View abstract.
  • Ishikawa H, Akedo I, Umesaki Y, et al. Randomized controlled trial of the effect of bifidobacteria-fermented milk on ulcerative colitis. J Am Coll Nutr 2003;22:56-63. View abstract.
  • Isolauri E, Juntunen M, Rautanen T, et al. A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 1991;88:90-7. View abstract.
  • Jauhiainen, T., Vapaatalo, H., Poussa, T., Kyronpalo, S., Rasmussen, M., and Korpela, R. Lactobacillus helveticus fermented milk lowers blood pressure in hypertensive subjects in 24-h ambulatory blood pressure measurement. Am J Hypertens 2005;18(12 Pt 1):1600-1605. View abstract.
  • Kaila, M., Isolauri, E., Soppi, E., Virtanen, E., Laine, S., and Arvilommi, H. Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain. Pediatr Res 1992;32(2):141-144. View abstract.
  • Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. View abstract.
  • Kato, K., Mizuno, S., Umesaki, Y., Ishii, Y., Sugitani, M., Imaoka, A., Otsuka, M., Hasunuma, O., Kurihara, R., Iwasaki, A., and Arakawa, Y. Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis. Aliment Pharmacol Ther 2004;20(10):1133-1141. View abstract.
  • Kawase, M., Hashimoto, H., Hosoda, M., Morita, H., and Hosono, A. Effect of administration of fermented milk containing whey protein concentrate to rats and healthy men on serum lipids and blood pressure. J Dairy Sci 2000;83(2):255-263. View abstract.
  • Koskinen TT, Virtanen HEK, Voutilainen S, Tuomainen TP, Mursu J, Virtanen JK. Intake of fermented and non-fermented dairy products and risk of incident CHD: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr. 2018;120(11):1288-1297. View abstract.
  • Laake, K. O., Bjorneklett, A., Aamodt, G., Aabakken, L., Jacobsen, M., Bakka, A., and Vatn, M. H. Outcome of four weeks' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scand J Gastroenterol 2005;40(1):43-51. View abstract.
  • Laake, K. O., Line, P. D., Grzyb, K., Aamodt, G., Aabakken, L., Roset, A., Hvinden, A. B., Bakka, A., Eide, J., Bjorneklett, A., and Vatn, M. H. Assessment of mucosal inflammation and blood flow in response to four weeks' intervention with probiotics in patients operated with a J-configurated ileal-pouch-anal-anastomosis (IPAA). Scand J Gastroenterol 2004;39(12):1228-1235. View abstract.
  • Lidbeck, A., Nord, C. E., Gustafsson, J. A., and Rafter, J. Lactobacilli, anticarcinogenic activities and human intestinal microflora. Eur J Cancer Prev 1992;1(5):341-353. View abstract.
  • Lund, B., Edlund, C., Barkholt, L., Nord, C. E., Tvede, M., and Poulsen, R. L. Impact on human intestinal microflora of an Enterococcus faecium probiotic and vancomycin. Scand J Infect Dis 2000;32(6):627-632. View abstract.
  • Mahe, S., Marteau, P., Huneau, J. F., Thuillier, F., and Tome, D. Intestinal nitrogen and electrolyte movements following fermented milk ingestion in man. Br J Nutr 1994;71(2):169-180. View abstract.
  • Marcos, A., Warnberg, J., Nova, E., Gomez, S., Alvarez, A., Alvarez, R., Mateos, J. A., and Cobo, J. M. The effect of milk fermented by yogurt cultures plus Lactobacillus casei DN-114001 on the immune response of subjects under academic examination stress. Eur J Nutr 2004;43(6):381-389. View abstract.
  • Marteau, P., Cuillerier, E., Meance, S., Gerhardt, M. F., Myara, A., Bouvier, M., Bouley, C., Tondu, F., Bommelaer, G., and Grimaud, J. C. Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women: a double-blind, randomized, controlled study. Aliment Pharmacol Ther 2002;16(3):587-593. View abstract.
  • Marteau, P., Vaerman, J. P., Dehennin, J. P., Bord, S., Brassart, D., Pochart, P., Desjeux, J. F., and Rambaud, J. C. Effects of intrajejunal perfusion and chronic ingestion of Lactobacillus johnsonii strain La1 on serum concentrations and jejunal secretions of immunoglobulins and serum proteins in healthy humans. Gastroenterol Clin Biol 1997;21(4):293-298. View abstract.
  • Marzotto, M., Maffeis, C., Paternoster, T., Ferrario, R., Rizzotti, L., Pellegrino, M., Dellaglio, F., and Torriani, S. Lactobacillus paracasei A survives gastrointestinal passage and affects the fecal microbiota of healthy infants. Res Microbiol 2006;157(9):857-866. View abstract.
  • Matsuoka K, Uemura Y, Kanai T, et al. Efficacy of Bifidobacterium breve Fermented Milk in Maintaining Remission of Ulcerative Colitis. Dig Dis Sci. 2018;63(7):1910-1919. View abstract.
  • Miki, K., Urita, Y., Ishikawa, F., Iino, T., Shibahara-Sone, H., Akahoshi, R., Mizusawa, S., Nose, A., Nozaki, D., Hirano, K., Nonaka, C., and Yokokura, T. Effect of Bifidobacterium bifidum fermented milk on Helicobacter pylori and serum pepsinogen levels in humans. J Dairy Sci 2007;90(6):2630-2640. View abstract.
  • Moreira TR, Leonhardt D, Conde SR. Influence of drinking a probiotic fermented milk beverage containing Bifidobacterium animalis on the symptoms of constipation. Arq Gastroenterol. 2017;54(3):206-210. View abstract.
  • Morimoto, K., Takeshita, T., Nanno, M., Tokudome, S., and Nakayama, K. Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers. Prev Med 2005;40(5):589-594. View abstract.
  • Morita, H., He, F., Kawase, M., Kubota, A., Hiramatsu, M., Kurisaki, J., and Salminen, S. Preliminary human study for possible alteration of serum immunoglobulin E production in perennial allergic rhinitis with fermented milk prepared with Lactobacillus gasseri TMC0356. Microbiol Immunol 2006;50(9):701-706. View abstract.
  • Nagao, F., Nakayama, M., Muto, T., and Okumura, K. Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the immune system in healthy human subjects. Biosci Biotechnol Biochem 2000;64(12):2706-2708. View abstract.
  • Narva, M., Karkkainen, M., Poussa, T., Lamberg-Allardt, C., and Korpela, R. Caseinphosphopeptides in milk and fermented milk do not affect calcium metabolism acutely in postmenopausal women. J Am Coll Nutr 2003;22(1):88-93. View abstract.
  • Narva, M., Nevala, R., Poussa, T., and Korpela, R. The effect of Lactobacillus helveticus fermented milk on acute changes in calcium metabolism in postmenopausal women. Eur J Nutr 2004;43(2):61-68. View abstract.
  • Ohashi, Y., Nakai, S., Tsukamoto, T., Masumori, N., Akaza, H., Miyanaga, N., Kitamura, T., Kawabe, K., Kotake, T., Kuroda, M., Naito, S., Koga, H., Saito, Y., Nomata, K., Kitagawa, M., and Aso, Y. Habitual intake of lactic acid bacteria and risk reduction of bladder cancer. Urol. Int. 2002;68(4):273-280. View abstract.
  • Pantoflickova, D., Corthesy-Theulaz, I., Dorta, G., Stolte, M., Isler, P., Rochat, F., Enslen, M., and Blum, A. L. Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis. Aliment Pharmacol Ther 2003;18(8):805-813. View abstract.
  • Parra, D., De Morentin, B. M., Cobo, J. M., Mateos, A., and Martinez, J. A. Monocyte function in healthy middle-aged people receiving fermented milk containing Lactobacillus casei. J Nutr Health Aging 2004;8(4):208-211. View abstract.
  • Parra, M. D., Martinez de Morentin, B. E., Cobo, J. M., Mateos, A., and Martinez, J. A. Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate-defense capacity in healthy middle-aged people. J Physiol Biochem 2004;60(2):85-91. View abstract.
  • Pedone CA, Arnaud CC, Postaire ER, et al. Multicentric study of the effect of milk fermented by Lactobacillus casei on the incidence of diarrhoea. Int J Clin Pract 2000;54:589-71. View abstract.
  • Pedone CA, Bernabeu AO, Postaire ER, et al. The effect of supplementation with milk fermented by Lactobacillus casei (strain DN-114 001) on acute diarrhoea in children attending day care centres. Int J Clin Pract 1999;53:179-84. View abstract.
  • Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  • Prodeus A, Niborski V, Schrezenmeir J, Gorelov A, Shcherbina A, Rumyantsev A. Fermented milk consumption and common infections in children attending day-care centers: A randomized trial. J Pediatr Gastroenterol Nutr. 2016;63(5):534-543. View abstract.
  • Radosavljevic, V., Ilic, M., Jankovic, S., and Djokic, M. [Diet in bladder cancer ethiopathogenesis]. Acta Chir Iugosl 2005;52(3):77-82. View abstract.
  • Rao, D. R., Pulusani, S. R., and Chawan, C. B. Role of fermented milk products in milk intolerance and other clinical conditions. Adv Nutr Res 1985;7:203-219. View abstract.
  • Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60. View abstract.
  • Rio, M. E., Zago Beatriz L., Garcia, H., and Winter, L. [The nutritional status change the effectiveness of a dietary supplement of lactic bacteria on the emerging of respiratory tract diseases in children]. Arch Latinoam Nutr 2002;52(1):29-34. View abstract.
  • Sairanen, U., Piirainen, L., Grasten, S., Tompuri, T., Matto, J., Saarela, M., and Korpela, R. The effect of probiotic fermented milk and inulin on the functions and microecology of the intestine. J Dairy Res 2007;74(3):367-373. View abstract.
  • Saito, Y., Hamanaka, Y., Saito, K., Takizawa, S., and Benno, Y. Stability of species composition of fecal bifidobacteria in human subjects during fermented milk administration. Curr Microbiol 2002;44(5):368-373. View abstract.
  • Salminen, E., Elomaa, I., Minkkinen, J., Vapaatalo, H., and Salminen, S. Preservation of intestinal integrity during radiotherapy using live Lactobacillus acidophilus cultures. Clin Radiol 1988;39(4):435-437. View abstract.
  • Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. View abstract.
  • Schiffrin, E. J., Rochat, F., Link-Amster, H., Aeschlimann, J. M., and Donnet-Hughes, A. Immunomodulation of human blood cells following the ingestion of lactic acid bacteria. J Dairy Sci 1995;78(3):491-497. View abstract.
  • Seppo, L., Jauhiainen, T., Poussa, T., and Korpela, R. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 2003;77(2):326-330. View abstract.
  • Shida K, Sato T, Iizuka R, et al. Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers. Eur J Nutr. 2017 Feb;56(1):45-53. doi: 10.1007/s00394-015-1056-1. Epub 2015 Sep 29. View abstract.
  • Silva, M. R., Dias, G., Ferreira, C. L., Franceschini, S. C., and Costa, N. M. Growth of preschool children was improved when fed an iron-fortified fermented milk beverage supplemented with Lactobacillus acidophilus. Nutr Res 2008;28(4):226-232. View abstract.
  • Simpson MR, Dotterud CK, Storrø O, Johnsen R, Øien T. Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial. BMC Dermatol. 2015;15:13. View abstract.
  • Solis, B., Nova, E., Gomez, S., Samartin, S., Mouane, N., Lemtouni, A., Belaoui, H., and Marcos, A. The effect of fermented milk on interferon production in malnourished children and in anorexia nervosa patients undergoing nutritional care. Eur J Clin Nutr 2002;56 Suppl 4:S27-S33. View abstract.
  • Songisepp, E., Kals, J., Kullisaar, T., Mandar, R., Hutt, P., Zilmer, M., and Mikelsaar, M. Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutr J 2005;4:22. View abstract.
  • Spanhaak, S., Havenaar, R., and Schaafsma, G. The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans. Eur J Clin Nutr 1998;52(12):899-907. View abstract.
  • St-Onge MP, Farnworth ER, Jones PJ. Consumption of fermented and nonfermented dairy products: effects on cholesterol concentrations and metabolism. Am J Clin Nutr 2000;71:674-81. View abstract.
  • Sykora, J., Valeckova, K., Amlerova, J., Siala, K., Dedek, P., Watkins, S., Varvarovska, J., Stozicky, F., Pazdiora, P., and Schwarz, J. Effects of a specially designed fermented milk product containing probiotic Lactobacillus casei DN-114 001 and the eradication of H. pylori in children: a prospective randomized double-blind study. J Clin Gastroenterol 2005;39(8):692-698. View abstract.
  • Takeda, K. and Okumura, K. Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity. J Nutr 2007;137(3 Suppl 2):791S-793S. View abstract.
  • Takeda, K., Suzuki, T., Shimada, S. I., Shida, K., Nanno, M., and Okumura, K. Interleukin-12 is involved in the enhancement of human natural killer cell activity by Lactobacillus casei Shirota. Clin Exp Immunol 2006;146(1):109-115. View abstract.
  • Tamura, M., Shikina, T., Morihana, T., Hayama, M., Kajimoto, O., Sakamoto, A., Kajimoto, Y., Watanabe, O., Nonaka, C., Shida, K., and Nanno, M. Effects of probiotics on allergic rhinitis induced by Japanese cedar pollen: randomized double-blind, placebo-controlled clinical trial. Int Arch Allergy Immunol 2007;143(1):75-82. View abstract.
  • Taylor, G. R. and Williams, C. M. Effects of probiotics and prebiotics on blood lipids. Br J Nutr 1998;80(4):S225-S230. View abstract.
  • Tidehag, P., Sandberg, A. S., Hallmans, G., Wing, K., Turk, M., Holm, S., and Grahn, E. Effect of milk and fermented milk on iron absorption in ileostomy subjects. Am J Clin Nutr 1995;62(6):1234-1238. View abstract.
  • Tormo Carnicer R., Infante Pina D., Rosello Mayans E., and Bartolome Comas R. [Intake of fermented milk containing Lactobacillus casei DN-114 001 and its effect on gut flora]. An Pediatr (Barc) 2006;65(5):448-453. View abstract.
  • Turchet, P., Laurenzano, M., Auboiron, S., and Antoine, J. M. Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study. J Nutr Health Aging 2003;7(2):75-77. View abstract.
  • Van Puyenbroeck K, Hens N, Coenen S, et al. Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home residents. Am J Clin Nutr. 2012;95(5):1165-71. View abstract.
  • van't Veer, P., Dekker, J. M., Lamers, J. W., Kok, F. J., Schouten, E. G., Brants, H. A., Sturmans, F., and Hermus, R. J. Consumption of fermented milk products and breast cancer: a case-control study in The Netherlands. Cancer Res 1989;49(14):4020-4023. View abstract.
  • Vesa, T. H., Marteau, P., Zidi, S., Briet, F., Pochart, P., and Rambaud, J. C. Digestion and tolerance of lactose from yoghurt and different semi-solid fermented dairy products containing Lactobacillus acidophilus and bifidobacteria in lactose maldigesters--is bacterial lactase important? Eur J Clin Nutr 1996;50(11):730-733. View abstract.
  • Wang, M. F., Lin, H. C., Wang, Y. Y., and Hsu, C. H. Treatment of perennial allergic rhinitis with lactic acid bacteria. Pediatr Allergy Immunol 2004;15(2):152-158. View abstract.
  • Wenus, C., Goll, R., Loken, E. B., Biong, A. S., Halvorsen, D. S., and Florholmen, J. Prevention of antibiotic-associated diarrhoea by a fermented probiotic milk drink. Eur J Clin Nutr 2008;62(2):299-301. View abstract.
  • Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. View abstract.
  • Yamamoto, N. and Takano, T. Antihypertensive peptides derived from milk proteins. Nahrung 1999;43(3):159-164. View abstract.
  • Yamano, T., Iino, H., Takada, M., Blum, S., Rochat, F., and Fukushima, Y. Improvement of the human intestinal flora by ingestion of the probiotic strain Lactobacillus johnsonii La1. Br J Nutr 2006;95(2):303-312. View abstract.
  • Yang, Y. X., He, M., Hu, G., Wei, J., Pages, P., Yang, X. H., and Bourdu-Naturel, S. Effect of a fermented milk containing Bifidobacterium lactis DN-173010 on Chinese constipated women. World J Gastroenterol 2008;14(40):6237-6243. View abstract.
  • Zeng, J., Li, Y. Q., Zuo, X. L., Zhen, Y. B., Yang, J., and Liu, C. H. Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2008;28(8):994-1002. View abstract.

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