Herbe de Joseph, Herbe Sacrée, Herbe Sainte, Hiope, Hisopo, Hissopo, Hyssopus officinalis, Hysope, Hysope Officinale, Jufa, Rabo De Gato, Ysop.


Overview Information

Hyssop is a flowering plant. It grows in southern Europe. The parts that grow above ground are used to make medicine.

Hyssop is used for digestive and intestinal problems, infection of the airways, poor circulation, skin problems, and other conditions, but there is no good scientific evidence to support these uses.

In foods, hyssop oil and extract are used as a flavoring.

In manufacturing, hyssop oil is used as a fragrance in soaps and cosmetics.

How does it work?

The chemicals in hyssop may affect the heart, increase secretions in the lungs, and protect the stomach from ulcers.


Uses & Effectiveness?

Insufficient Evidence for

  • Liver and gallbladder problems.
  • Intestinal problems.
  • Common cold.
  • Sore throat.
  • Asthma.
  • Infection of the airways.
  • Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs).
  • Gas.
  • Colic.
  • Loss of appetite.
  • Poor circulation.
  • Skin conditions (bruises, rashes, burns, frostbite), when applied to the skin.
  • Menstrual cramps.
  • Other conditions.
More evidence is needed to rate the effectiveness of hyssop for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Hyssop is LIKELY SAFE for most people in the amounts commonly found in foods. There isn't enough reliable information to know if it is safe when used in larger amounts. But some animal studies suggest that hyssop oil may cause serious adverse effects at low doses.

When applied to the skin: There isn't enough reliable information to know if hyssop is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy: It is LIKELY UNSAFE to use hyssop during pregnancy because it might cause the uterus to contract or start menstruation. These effects could lead to a miscarriage.

Breast-feeding: There isn't enough reliable information to know if hyssop is safe to use when breast-feeding. Stay on the safe side and avoid use.



We currently have no information for HYSSOP Interactions.



The appropriate dose of hyssop depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for hyssop. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2004;24(12):1084-1086. View abstract.
  • Gollapudi, S., Sharma, H. A., Aggarwal, S., Byers, L. D., Ensley, H. E., and Gupta, S. Isolation of a previously unidentified polysaccharide (MAR-10) from Hyssop officinalis that exhibits strong activity against human immunodeficiency virus type 1. Biochem.Biophys.Res.Commun. 5-5-1995;210(1):145-151. View abstract.
  • Kreis, W., Kaplan, M. H., Freeman, J., Sun, D. K., and Sarin, P. S. Inhibition of HIV replication by Hyssop officinalis extracts. Antiviral Res. 1990;14(6):323-337. View abstract.
  • Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  • Manufacturer: Nature's Answer. Hanppange, NY.
  • Manufacturer: Nature's Way. Springville, UT.
  • Millet Y, Jouglard J, Steinmetz MD, et al. Toxicity of some essential plant oils. Clinical and experimental study. Clin Toxicol 1981;18:1485-98. View abstract.
  • Tahir M, Rahman MA, Khushtar M. Gastroprotective effect of Hyssopus officinalis L. leaves via reduction of oxidative stress in indomethacin-induced gastric ulcer in experimental rats. Drug Chem Toxicol. 2019:1-10. Online ahead of print. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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