QUILLAIA
Arbre à Savon, Bois de Panama, China Bark, Murillo Bark, Panama Bark, Quillaja, Quillaja saponaria, Quillay, Savonnier, Soap Tree, Soap Tree Bark, Soapbark.<br/><br/>
Uses & Effectiveness
Insufficient Evidence for
TAKEN BY MOUTH
- Cough.
- Bronchitis.
- Breathing problems.
- Other conditions.
- Skin sores.
- Athlete’s foot.
- Itchy scalp.
- Dandruff.
- Vaginal discharge.
- Other conditions.
Side Effects & Safety
Quillaia seems to be safe when taken in food amounts. But it might be UNSAFE when taken by mouth in medicinal doses. Plants such as quillaia that contain high amounts of tannins can cause stomach and intestinal disturbances, and kidney and liver damage. Quillaia also contains chemicals called oxalates that can lower bloodcalcium levels and cause kidney stones. Quillaia use can also cause diarrhea, stomach pain, serious breathing problems, convulsions, coma, red blood cell destruction, and kidney failure. Quillaia can also irritate and damage the lining of the mouth, throat, and digestive tract.It is not known if quillaia is safe when put on the skin or in the vagina. If inhaled, the powder can cause sneezing.
Special Precautions & Warnings:
While quillaia isn’t safe for anyone, some people are at even greater risk for serious side effects. Be especially careful not to take quillaia if you have any of the following conditions:Pregnancy and breast-feeding: Quillaia might be UNSAFE for both mother and infant. Avoid use.
Stomach and intestinal (gastrointestinal, GI) problems: Quillaia can irritate the GI tract. Don’t use it if you have a stomach or intestinal disorder.
Kidney disease: The oxalate in quillaia can cause kidney stones. Don’t use it if you have kidney disease or a history of kidney stones.
Interactions
Moderate Interaction
Be cautious with this combination
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Medications taken by mouth (Oral drugs) interacts with QUILLAIA
Quillaia contains a large amount of chemicals called tannins. Tannins absorb substances in the stomach and intestines. Taking quillaia along with medications taken by mouth can decrease how much medicine your body absorbs, and decrease the effectiveness of your medicine. To prevent this interaction, take quillaia at least one hour after medications you take by mouth.
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Metformin (Glucophage) interacts with QUILLAIA
Metformin (Glucophage) is used to help decrease blood sugar. Quillaia might decrease how much metformin (Glucophage) the body absorbs. Taking quillaia along with metformin (Glucophage) might decrease the effectiveness of metformin (Glucophage) for lowering blood sugar. Monitor your blood sugar closely. The dose of your metformin (Glucophage) might need to be changed.
Dosing
The appropriate dose of quillaia depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for quillaia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
REFERENCES:
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Pillion DJ, Amsden JA, Kensil CR, et al. Structure-function relationship among Quillaja saponins serving as excipients for nasal and ocular delivery of insulin. J Pharm Sci 1996;85:518-24. View abstract.
- Recchia J, Lurantos MH, Amsden JA, et al. A semisynthetic Quillajasaponin as a drug delivery agent for aminoglycoside antibiotics. Pharm Res 1995;12:1917-23. View abstract.
- Sidhu GS, Oakenfull DG. A mechanism for the hypocholesterolaemic activity of saponins. Br J Nutr 1986;55:643-9. View abstract.
- Wu JY, Gardner BH, Murphy CI, et al. Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J Immunol 1992;148:1519-25. View abstract.
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