Corydale, Corydale Bulbeuse, Corydale Creuse, Corydale à Tubercule Creux, Corydalis cava, Corydalis tuberosa, Corydalis Yanhusuo Rhizome, Dai Ding, Early Fumitory, Fumeterre Creuse, Squirrel Corn, Yanhusuo, Yuan Hu Suo.


Overview Information

Corydalis is a plant used in China. People use the tuber and root for medicine.

Corydalis is used for stomach problems, emotional problems, and other conditions. However there is not much research to support the use of corydalis for any condition.

How does it work?

There isn't enough information to know how corydalis might work.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of corydalis for these uses.

Side Effects

Side Effects & Safety

When taken by mouth for a short time, corydalis is POSSIBLY SAFE. Some research shows that corydalis extract is safe to use for up to 4 weeks. However, when too much is taken, corydalis can cause spasms and muscle tremors.

Special Precautions & Warnings:

Pregnancy and breast-feeding: It's UNSAFE to take corydalis if you are pregnant. It might start your period and cause the uterus to contract. This could cause a miscarriage.

Breast-feeding: Not enough is known about the safety of using corydalis if you are breast-feeding. It's best to avoid using it.



We currently have no information for CORYDALIS Interactions.



The appropriate dose of corydalis depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for corydalis. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • [Radix Salviae miltiorrhizae-Rhizoma Corydalis decoction and nicotinic acid solution iontophoresis to the precordium in the treatment of angina pectoris]. Zhonghua Yi.Xue.Za Zhi. 1974;3:166-168. View abstract.
  • Chen, Q. M., Ye, Y. C., and Xu, Z. J. [Experimental study on the effect of Corydalis stricta Steph. against Echinococcus granulosus protoscolices in man]. Zhonghua Wai Ke.Za Zhi. 1986;24(12):768-9, 783. View abstract.
  • Huang, X. N., Liu, G. X., and Zhang, Y. [Tranquillizing effects of total alkaloids of Corydalis saxicola (author's transl)]. Zhongguo Yao Li Xue.Bao. 1981;2(3):156-159. View abstract.
  • Li, H. L., Zhang, W. D., Liu, R. H., Zhang, C., Han, T., Wang, X. W., Wang, X. L., Zhu, J. B., and Chen, C. L. Simultaneous determination of four active alkaloids from a traditional Chinese medicine Corydalis saxicola Bunting. (Yanhuanglian) in plasma and urine samples by LC-MS-MS. J Chromatogr.B Analyt.Technol.Biomed.Life Sci. 2-2-2006;831(1-2):140-146. View abstract.
  • Ma, S. X. [Clinical studies in the treatment of premature systoles with alkaloids of Corydalis yanhusuo]. Zhonghua Xin.Xue.Guan.Bing.Za Zhi. 1983;11(1):6-10. View abstract.
  • Wang, D. J., Mao, H. Y., and Lei, M. [Rotundium in the treatment of atrial fibrillation]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1993;13(8):455-7, 451. View abstract.
  • Wang, H. X. and Ng, T. B. Examination of lectins, polysaccharopeptide, polysaccharide, alkaloid, coumarin and trypsin inhibitors for inhibitory activity against human immunodeficiency virus reverse transcriptase and glycohydrolases. Planta Med 2001;67(7):669-672. View abstract.
  • Xie, C., Kokubun, T., Houghton, P. J., and Simmonds, M. S. Antibacterial activity of the Chinese traditional medicine, Zi Hua Di Ding. Phytother.Res. 2004;18(6):497-500. View abstract.
  • Yuan, C. S., Mehendale, S. R., Wang, C. Z., Aung, H. H., Jiang, T., Guan, X., and Shoyama, Y. Effects of Corydalis yanhusuo and Angelicae dahuricae on cold pressor-induced pain in humans: a controlled trial. J.Clin.Pharmacol. 2004;44(11):1323-1327. View abstract.
  • Zhang, L., Yang, L. W., and Yang, L. J. [Relation between Helicobacter pylori and pathogenesis of chronic atrophic gastritis and the research of its prevention and treatment]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1992;12(9):521-526. View abstract.
  • Jung HK, Lee KJ, Choi MG, et al. Efficacy of DA-9701 (Motilitone) in functional dyspepsia compared to pantoprazole: a multicenter, randomized, double-blind, non-inferiority study. J Neurogastroenterol Motil 2016;22(2):254-63. View abstract.
  • Kim SY, Woo HS, Kim KO, et al. DA-9701 improves colonic transit time and symptoms in patients with functional constipation: a prospective study. J Gastroenterol Hepatol 2017;32(12):1943-8. View abstract.
  • Li, Y., Xu, C., Zhang, Q., Liu, J. Y., and Tan, R. X. In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases. J Ethnopharmacol 4-26-2005;98(3):329-333. View abstract.
  • Park CH, Kim HS, Lee SK. Effects of the new prokinetic agent DA-9701 formulated with corydalis tuber and pharbitis seed in patients with minimal change esophagitis: a bicenter, randomized, double blind, placebo-controlled Study. J Neurogastroenterol Motil 2014;20(3):338-46. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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