The fruit of European barberry is most commonly used traditionally for gastrointestinal (GI) tract discomforts such as heartburn, stomachcramps, constipation, and lack of appetite. However, there is no scientific evidence to support these uses.
In foods, European barberry fruit is used in making jam, jellies, and wine.
In manufacturing, the fruit syrup is used for masking tastes in medicines.
How does it work ?
Uses & Effectiveness ?
Insufficient Evidence for
- Acne. Early research shows that taking European barberry capsules for 4 weeks reduces acne in teens.
- Overgrowth of bacteria in the vagina. Applying a cream with European barberry and metronidazole to the vagina seems to stop bacterial vaginosis infection from happening again.
- Tooth plaque. Early research shows that brushing the teeth with a European barberry extract gel for 3 weeks reduces dental plaque. The effects appear to be similar to a commercial toothpaste (Colgate).
- Diabetes. Early research shows that taking European barberry juice by mouth for 8 weeks improves blood sugar levels in people with type 2 diabetes.
- A mild form of gum disease (gingivitis). Early research shows that brushing the teeth with a European barberry extract gel for 3 weeks reduces gingivitis.
- High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Research shows that European barberry might decrease levels of cholesterol and other fats in the blood in people with diabetes, metabolic syndrome, or liver disease. But the effects of European barberry on lipids in people with hyperlipidemia are not clear.
- Back pain.
- Bladder problems.
- Heart and circulation problems.
- Kidney problems.
- Liver problems.
- Lung problems.
- Non-cancerous breast disorders.
- Rheumatoid arthritis (RA).
- Skin infection caused by Leishmania parasites (Leishmania lesions).
- Spleen problems.
- Stomach cramps.
- Withdrawal from heroin, morphine, and other opioid drugs.
- Other conditions.
When applied to the skin: European barberry extract is POSSIBLY SAFE when used on the skin.
Special Precautions and Warnings
Pregnancy and breast-feeding: Don't use European barberry by mouth if you are pregnant or breast-feeding. It is LIKELY UNSAFE for your baby. The berberine in European barberry can pass from a mother's body into her unborn child through the placenta. Brain damage has developed in newborns exposed to berberine. Similarly, berberine, as well as other harmful chemicals in European barberry, can be transferred to an infant through breast milk, and might cause brain damage.
Bleeding disorder: European barberry contains a chemical called berberine. Berberine might slow blood clotting and increase the risk of bleeding. In theory, European barberry might make bleeding disorders worse.
Diabetes: European barberry might lower blood sugar levels. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use European barberry in amounts larger than the amounts normally found in food.
Low blood pressure: European barberry might lower blood pressure. In theory, taking European barberry might make blood pressure become too low in people with low blood pressure.
Surgery: European barberry contains a chemical called berberine. There is concern that berberine from European barberry might prolong bleeding or slow down the nervous system during and after surgery. European barberry might also interfere with blood sugar control during and after surgery. Stop taking European barberry at least 2 weeks before a scheduled surgery.
Cyclosporine (Neoral, Sandimmune) interacts with EUROPEAN BARBERRY
The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. European barberry might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). This might cause there to be too much cyclosporine (Neoral, Sandimmune) in the body and potentially cause side effects.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with EUROPEAN BARBERRY
Some medications are changed and broken down by the liver. European barberry might decrease how quickly the liver breaks down some medications. Taking European barberry along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before taking European barberry, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include cyclosporin (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.
Drying medications (Anticholinergic drugs) interacts with EUROPEAN BARBERRY
European barberry might increase levels of certain chemicals in the body that work in the brain, heart, and elsewhere. Some drying medications called "anticholinergic drugs" can also affect these same chemicals, but in a different way. These drying medications might decrease the effects of European barberry and European barberry might decrease the effects of drying medications.
Some of these drying medications include atropine, scopolamine, some medications used for allergies (antihistamines), and some medications used for depression (antidepressants).
Medications for diabetes (Antidiabetes drugs) interacts with EUROPEAN BARBERRY
European barberry might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking European barberry along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Medications for high blood pressure (Antihypertensive drugs) interacts with EUROPEAN BARBERRY
European barberry might decrease blood pressure in some people. Taking European barberry along with medications used for lowering high blood pressure might cause your blood pressure to go too low. Do not take too much European barberry if you are taking medications for high blood pressure.
Some medications for high blood pressure include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with EUROPEAN BARBERRY
European barberry might slow blood clotting. Taking European barberry along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Sedative medications (CNS depressants) interacts with EUROPEAN BARBERRY
European barberry might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking European barberry along with sedative medications might cause too much sleepiness. Taking European barberry along with sedative medications used in surgery might cause prolonged sedation.
Some sedative medications include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), and others.
Various medications used for glaucoma, Alzheimer disease, and other conditions (Cholinergic drugs) interacts with EUROPEAN BARBERRY
European barberry might increase certain chemicals in the brain, heart, and elsewhere in the body. Some medications used for glaucoma, Alzheimer disease, and other conditions also affect these chemicals. Taking European barberry with these medications might increase the chance of side effects.
European barberry might increase certain chemicals in the brain, heart, and elsewhere in the body. Some medications used for glaucoma, Alzheimer disease, and other conditions also affect these chemicals. Taking European barberry with these medications might increase the chance of side effects.
Be cautious with this combination
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