MAITAKE MUSHROOM

OTHER NAME(S):

Champignon Dansant, Champignon des Fous Dansants, Champignon Maitake, Dancing Mushroom, Grifola, Grifola frondosa, Hen of the Woods, Hongo Maitake, King of Mushrooms, Maitake, Monkey's Bench, Mushroom, Ram's Head, Roi des Champignons, Sheep's Head, Shelf Fungi.<br/><br/>

Overview

Overview Information

Maitake is a type of mushroom. People use it to make medicine.

Some people take maitake mushroom by mouth for infertility due to a condition called polycystic ovary syndrome (PCOS). It is also used to treat cancer and to relieve some of the side effects of chemotherapy. There is limited scientific evidence to support these and other uses.

How does it work?

Maitake mushroom contains chemicals which might help fight tumors, stimulate the immune system, and lower blood sugar levels.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Diabetes. Early research shows that taking maitake mushroom polysaccharides (MMP) by mouth may lower blood sugar in people with diabetes.
  • An ovary disorder known as polycystic ovary syndrome (PCOS). Early research shows that taking a specific dietary supplement containing maitake mushroom extract can improve ovulation in women whose periods have stopped due to PCOS. Maitake mushroom does not appear to be as effective as the drug clomiphene for PCOS, but the combination of these two agents may be more effective than either one alone for improving ovulation.
  • Cancer.
  • HIV/AIDS.
  • Chronic fatigue syndrome (CFS).
  • Hepatitis.
  • Hay fever.
  • High blood pressure.
  • High cholesterol.
  • Weight loss or control.
  • Chemotherapy support.
  • Other conditions.
More evidence is needed to rate maitake mushroom for these uses.

Side Effects

Side Effects & Safety

Maitake mushroom is POSSIBLY SAFE for most people when taken by mouth as medicine, but there isn't much information about the potential side effects. Some people have reported nausea after taking maitake mushroom.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking maitake mushroom if you are pregnant or breast-feeding . Stay on the safe side and avoid use..

Diabetes: Maitake mushroom might lower blood sugar levels. Your diabetes medications might need to be adjusted by your healthcare provider.

Low blood pressure: Maitake mushroom can lower blood pressure. In theory, taking maitake mushroom might make blood pressure become too low in people with low blood pressure.

Surgery: Maitake mushroom might affect blood sugar levels, making blood sugar control difficult during and after surgery. Stop using maitake mushroom at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Medications for diabetes (Antidiabetes drugs) interacts with MAITAKE MUSHROOM

    Maitake mushroom might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking maitake mushroom along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br/><br/> Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Dosing

Dosing

The appropriate dose of maitake mushroom depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for maitake mushroom. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. View abstract.
  • Heo, H. J., Cho, H. Y., Hong, B., Kim, H. K., Heo, T. R., Kim, E. K., Kim, S. K., Kim, C. J., and Shin, D. H. Ursolic acid of Origanum majorana L. reduces Abeta-induced oxidative injury. Mol.Cells 2-28-2002;13(1):5-11. View abstract.
  • Lamien-Meda, A., Lukas, B., Schmiderer, C., Franz, C., and Novak, J. Validation of a quantitative assay of arbutin using gas chromatography in Origanum majorana and Arctostaphylos uva-ursi extracts. Phytochem.Anal. 2009;20(5):416-420. View abstract.
  • Leeja, L. and Thoppil, J. E. Antimicrobial activity of methanol extract of Origanum majorana L. (Sweet marjoram). J Environ.Biol 2007;28(1):145-146. View abstract.
  • Mohamed MS, Saad HH, and Abd El Khalek MG. Daily consumption of marjoram oil improve the health status of patients with asthma. Pakistan Journal of Nutrition. 2008;7(2):312-316.
  • Nakatani, N. Phenolic antioxidants from herbs and spices. Biofactors 2000;13(1-4):141-146. View abstract.
  • Orhan, I., Kartal, M., Kan, Y., and Sener, B. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z.Naturforsch.C. 2008;63(7-8):547-553. View abstract.
  • Ou, M. C., Hsu, T. F., Lai, A. C., Lin, Y. T., and Lin, C. C. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet.Gynaecol.Res 2012;38(5):817-822. View abstract.
  • Ozbayer, C., Degirmenci, I., and Kurt, H. Antioxidant and free radical-scavenging properties of Stevia rebaudiana (Bertoni) extracts and L-NNA in streptozotocine-nicotinamide induced diabetic rat liver [Turkish]. Turkiye Klinikleri Journal of Medical Sciences 2011;31(1):51-60.
  • Petr, J., Vitkova, K., Ranc, V., Znaleziona, J., Maier, V., Knob, R., and Sevcik, J. Determination of some phenolic acids in Majorana hortensis by capillary electrophoresis with online electrokinetic preconcentration. J.Agric.Food Chem. 6-11-2008;56(11):3940-3944. View abstract.
  • Rau, O., Wurglics, M., Dingermann, T., Abdel-Tawab, M., and Schubert-Zsilavecz, M. Screening of herbal extracts for activation of the human peroxisome proliferator-activated receptor. Pharmazie 2006;61(11):952-956. View abstract.
  • Rodrigues, M. R., Caramao, E. B., Arce, L., Rios, A., and Valcarcel, M. Determination of monoterpene hydrocarbons and alcohols in Majorana hortensis Moench by micellar electrokinetic capillary chromatographic. J Agric Food Chem 7-17-2002;50(15):4215-4220. View abstract.
  • Sarer, E., Scheffer, J. J., and Baerheim, Svendsen A. Monoterpenes in the Essential Oil of Origanum majorana. Planta Med 1982;46(12):236-239. View abstract.
  • Triantaphyllou, K., Blekas, G., and Boskou, D. Antioxidative properties of water extracts obtained from herbs of the species Lamiaceae. Int J Food Sci Nutr 2001;52(4):313-317. View abstract.
  • Vagi, E., Rapavi, E., Hadolin, M., Vasarhelyine, Peredi K., Balazs, A., Blazovics, A., and Simandi, B. Phenolic and triterpenoid antioxidants from Origanum majorana L. herb and extracts obtained with different solvents. J Agric Food Chem 1-12-2005;53(1):17-21. View abstract.
  • Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. View abstract.
  • Anderson C, Lis-Balchin M, Kirk-Smith M. Evaluation of massage with essential oils on childhood atopic eczema. Phytother Res 2000;14(6):452-6. View abstract.
  • Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. View abstract.
  • Bina F, Rahimi R. Sweet marjoram: a review of ethnopharmacology, phytochemistry, and biological activities. J Evid Based Complementary Altern Med 2017;22(1):175-85. View abstract.
  • Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  • Haj-Husein I, Tukan S, Alkazaleh F. The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomized controlled pilot study. J Hum Nutr Diet 2016;29(1):105-11. View abstract.
  • Klekamp BG, Bodager D, Matthews SD. Use of surveillance systems in detection of a ciguatera fish poisoning outbreak - Orange cCounty, Florida, 2014. MMWR Morb Mortal Wkly Rep. 2015;64(40):1142-4. View abstract.
  • Lukas B, Schmiderer C, Mitteregger U, Novak J. Arbutin in marjoram and oregano. Food Chem 2010;121(1):185-90.
  • Spelman, K., Burns, J., Nichols, D., Winters, N., Ottersberg, S., and Tenborg, M. Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators. Altern.Med.Rev. 2006;11(2):128-150. View abstract.
  • Suzuki, I., Hashimoto, K., Oikawa, S., Sato, K., Osawa, M., and Yadomae, T. Antitumor and immunomodulating activities of a beta-glucan obtained from liquid-cultured Grifola frondosa. Chem Pharm Bull (Tokyo) 1989;37(2):410-413. View abstract.
  • Suzuki, I., Itani, T., Ohno, N., Oikawa, S., Sato, K., Miyazaki, T., and Yadomae, T. Antitumor activity of a polysaccharide fraction extracted from cultured fruiting bodies of Grifola frondosa. J Pharmacobiodyn. 1984;7(7):492-500. View abstract.
  • Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. View abstract.
  • Tanaka, H., Tsunematsu, K., Nakamura, N., Suzuki, K., Tanaka, N., Takeya, I., Saikai, T., and Abe, S. Successful treatment of hypersensitivity pneumonitis caused by Grifola frondosa (Maitake) mushroom using a HFA-BDP extra-fine aerosol. Intern.Med. 2004;43(8):737-740. View abstract.
  • Wu, M. J., Cheng, T. L., Cheng, S. Y., Lian, T. W., Wang, L., and Chiou, S. Y. Immunomodulatory properties of Grifola frondosa in submerged culture. J Agric.Food Chem 4-19-2006;54(8):2906-2914. View abstract.
  • Yang, D., Li, S., Wang, H., Li, X., Liu, S., Han, W., Hao, J., and Zhang, H. [Prevention of postoperative recurrence of bladder cancer: a clinical study]. Zhonghua Wai Ke.Za Zhi. 1999;37(8):464-465. View abstract.
  • Adachi K, Nanba H, Kuroda H. Potentiation of host-mediated antitumor activity in mice by beta-glucan obtained from Grifola frondosa (maitake). Chem Pharm Bull (Tokyo) 1987;35:262-70. View abstract.
  • Borchers AT, Stern JS, Hackman RM, et al. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med 1999;221:281-293. View abstract.
  • Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Complement Med 2010;16:1295-9. View abstract.
  • Han C, Cui B. Pharmacological and pharmacokinetic studies with agaricoglycerides, extracted from Grifola frondosa, in animal models of pain and inflammation. Inflammation 2012;35(4):1269-75. View abstract.
  • Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. View abstract.
  • Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. View abstract.
  • Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. View abstract.
  • Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. View abstract.
  • Kubo K, Aoki H, Nanba H. Anti-diabetic activity present in the fruit body of Grifola frondosa (Maitake). I. Biol Pharm Bull 1994;17:1106-10. View abstract.
  • Kubo K, Nanba H. The effect of maitake mushrooms on liver and serum lipids. Alt Ther Health Med 1996;2:62-6. View abstract.
  • Nanba H, Kubo K. Effect of Maitake D-fraction on cancer prevention. Ann N Y Acad Sci 1997;833:204-7. View abstract.
  • Nanba H. Activity of maitake D-fraction to inhibit carcinogenesis and metastasis. Ann N Y Acad Sci 1995;768:243-5. View abstract.
  • Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. View abstract.
  • Adachi, Y., Ohno, N., and Yadomae, T. Activation of murine kupffer cells by administration with gel-forming (1-->3)-beta-D-glucan from Grifola frondosa. Biol Pharm Bull 1998;21(3):278-283. View abstract.
  • Adachi, Y., Okazaki, M., Ohno, N., and Yadomae, T. Enhancement of cytokine production by macrophages stimulated with (1-- >3)-beta-D-glucan, grifolan (GRN), isolated from Grifola frondosa. Biol Pharm Bull 1994;17(12):1554-1560. View abstract.
  • Bae, J. T., Sim, G. S., Lee, D. H., Lee, B. C., Pyo, H. B., Choe, T. B., and Yun, J. W. Production of exopolysaccharide from mycelial culture of Grifola frondosa and its inhibitory effect on matrix metalloproteinase-1 expression in UV-irradiated human dermal fibroblasts. FEMS Microbiol.Lett 10-15-2005;251(2):347-354. View abstract.
  • Chang, R. Functional properties of edible mushrooms. Nutr Rev 1996;54(11 Pt 2):S91-S93. View abstract.
  • Cui, F. J., Li, Y., Xu, Y. Y., Liu, Z. Q., Huang, D. M., Zhang, Z. C., and Tao, W. Y. Induction of apoptosis in SGC-7901 cells by polysaccharide-peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Toxicol In Vitro 2007;21(3):417-427. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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