Bois de la Puissance, Bois de la Puissance Sexuelle, Marapuama, Miranta, Muira-Puama, Muirapuama, Potency Wood, Ptychopetali lignum, Ptychopetalum olacoides, Ptychopetalum uncinatum.


Overview Information

Muira puama is a bush that grows in the Amazon region. The wood and root are used to make medicine.

Muira puama is used for sexual disorders, increasing sexual desire in healthy people, menstrual disorders, joint pain, and other conditions, but there is no good scientific evidence to support these uses.

How does it work?

It is unclear which, if any, chemicals in muira puma have effects on the body.


Uses & Effectiveness?

Insufficient Evidence for

  • Athletic performance.
  • Brain and nerve disorders.
  • Erectile dysfunction (ED).
  • Indigestion (dyspepsia).
  • Joint pain.
  • Loss of appetite.
  • Menstrual disorders.
  • Sexual problems that prevent satisfaction during sexual activity.
  • Other conditions.
More evidence is needed to rate the effectiveness of muira puama for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Muira puama is POSSIBLY SAFE when taken by mouth at a dose of 500-1050 mg daily for up to 1 month. There isn't enough reliable information to know if muira puama is safe to use for more than 1 month or what the side effects might be.

When applied to the skin: There isn't enough reliable information to know if muira puama is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if muira puama is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.



We currently have no information for MUIRA PUAMA Interactions.



The appropriate dose of muira puama depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for muira puama. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Antunes, E., Gordo, W. M., de Oliveira, J. F., Teixeira, C. E., Hyslop, S., and De, Nucci G. The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama and its constituents. Phytother.Res. 2001;15(5):416-421. View abstract.
  • da Silva, A. L., Piato, A. L., Bardini, S., Netto, C. A., Nunes, D. S., and Elisabetsky, E. Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice. J Ethnopharmacol. 2004;95(2-3):199-203. View abstract.
  • Siqueira, I. R., Cimarosti, H., Fochesatto, C., Nunes, D. S., Salbego, C., Elisabetsky, E., and Netto, C. A. Neuroprotective effects of Ptychopetalum olacoides Bentham (Olacaceae) on oxygen and glucose deprivation induced damage in rat hippocampal slices. Life Sci 8-27-2004;75(15):1897-1906. View abstract.
  • Siqueira, I. R., Fochesatto, C., da Silva, A. L., Nunes, D. S., Battastini, A. M., Netto, C. A., and Elisabetsky, E. Ptychopetalum olacoides, a traditional Amazonian "nerve tonic", possesses anticholinesterase activity. Pharmacol.Biochem.Behav 2003;75(3):645-650. View abstract.
  • Waynberg J. Aphrodisiacs: contribution to the clinical validation of the traditional use of Ptychopetalum guyanna. The First International Congress on Ethnopharmacology 1990;
  • Waynberg J. Male sexual asthenia - interest in a traditional plant-derived medication. Ethnopharmacology 1995.
  • Waynberg J. Unpublished study of HV 430's effects on healthy males with sexual dysfunction. 2001.
  • Waynberg, J. and Brewer, S. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Adv Ther 2000;17(5):255-262. View abstract.
  • Nguyen S, Rajfer J, Shaheen M. Safety and efficacy of daily Revactin in men with erectile dysfunction: a 3-month pilot study. Transl Androl Urol. 2018;7(2):266-73. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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