Aframomum melegueta, Afrika Kakulesi, Alligator Pepper, Amomum melegueta, Graine de Paradis, Graines de Guinée, Grani de Meleguetta, Granos de Guinea, Granos del Paraíso, Guinea Grains, Guinea Pepper, Guineapfeffer, Khayrbûâ, Malagettapfeffer, Melagueta, Malaguette, Malagvet, Maleguetta Pepper, Mallaguetta Pepper, Maniguetta, Maniguette, Maniquette, Melegeti Aframon, Melegueta, Melegueta Pepper, Meleguetapfeffer, Meleguetta Pepper, Méléguette, Paradieskörner, Paradiskorn, Pimienta Melegueta, Plante du Paradis, Poivre de Guinée, Poivre du Paradis, Qâqullah Dhakar, Rajskiye Zyorna, Semence de Paradis, Sha Ren.


Overview Information

Grains of paradise is a plant that is related to ginger. The seeds are used as a spice and as medicine.

Be careful not to confuse grains of paradise with capsicum. Both are known as grains of paradise.

People use grains of paradise for conditions such as diarrhea, heart disease, obesity, and many others, but there is no good scientific evidence to support these uses.

How does it work?

Chemicals in the seeds of grains of paradise seem to decrease swelling (inflammation), kill certain bacteria, and help burn body fat.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of grains of paradise for this use.

Side Effects

Side Effects & Safety

When taken by mouth: Grains of paradise extracts are POSSIBLY SAFE for most adults when taken by mouth, short term. There isn't enough reliable information to know if grains of paradise extracts are safe when taken by mouth long-term.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if grains of paradise is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.



We currently have no information for GRAINS OF PARADISE Interactions.



The appropriate dose of grains of paradise depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for grains of paradise. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Hattori H, Yamauchi K, Onwona-Agyeman S, Mitsunaga T. Identification of vanilloid compounds in grains of paradise and their effects on sympathetic nerve activity. J Sci Food Agric 2018;98(12):4742-8. View abstract.
  • Ilic N, Schmidt BM, Poulev A, Raskin I. Toxicological evaluation of Grains of Paradise (Aframomum melegueta) [Roscoe] K. Shum. J Ethnopharmacol 2010;127:352-6. View abstract.
  • Ilic NM, Dey M, Poulev AA, Logendra S, Kuhn PE, Raskin I. Anti-inflammatory activity of grains of paradise (Aframomum melegueta Schum) extract. J Agric Food Chem 2014;62(43):10452-7. View abstract.
  • Ngwoke KG, Chevallier O, Wirkom VK, Stevenson P, Elliott CT, Situ C. In vitro bactericidal activity of diterpenoids isolated from Aframomum melegueta K.Schum against strains of Escherichia coli, Listeria monocytogenes and Staphylococcus aureus. J Ethnopharmacol 2014;151(3):1147-54. View abstract.
  • Reid D. A handbook of Chinese healing herbs. Boston, MA:Shambhala, 1995.
  • Sugita J, Yoneshiro T, Hatano T, et al. Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men. Br J Nutr 2013;110(4):733-8. View abstract.
  • Sugita J, Yoneshiro T, Sugishima Y, et al. Daily ingestion of grains of paradise (Aframomum melegueta) extract increases whole-body energy expenditure and decreases visceral fat in humans. J Nutr Sci Vitaminol (Tokyo) 2014;60(1):22-7. View abstract.

Vitamins Survey

Have you ever purchased GRAINS OF PARADISE?

Did you or will you purchase this product in-store or online?

Where did you or where do you plan to purchase this product?

Where did you or where do you plan to purchase this product?

What factors influenced or will influence your purchase? (check all that apply)

Vitamins Survey

Where did you or where do you plan to purchase this product?

Do you buy vitamins online or instore?

What factors are most important to you? (check all that apply)

This survey is being conducted by the WebMD marketing sciences department.Read More

More Resources for GRAINS OF PARADISE

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty .