People use dandelion for conditions such as swelling (inflammation) of the tonsils (tonsillitis), infections of the kidney, bladder, or urethra (urinary tract infections or UTIs), and many others, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness ?
Insufficient Evidence for
- Swelling (inflammation) of the tonsils (tonsillitis). Early research shows that people who have had their tonsils removed recover faster if they eat soup containing dandelion compared to those who eat soup without dandelion.
- Gas (flatulence).
- Heart failure.
- Indigestion (dyspepsia).
- Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs).
- Joint pain.
- Other conditions.
Special Precautions and Warnings
Eczema: People with eczema seem to have a higher chance of having an allergic reaction to dandelion. If you have eczema, be sure to check with your healthcare provider before taking dandelion.
Bleeding disorders: Dandelion might slow blood clotting. In theory, taking dandelion might increase the risk for bruising and bleeding in people with bleeding disorders.
Ragweed allergy: People who are allergic to ragweed and related plants (daisies, chrysanthemums, marigolds) might be more likely to be allergic to dandelion. But conflicting data exists. If you have allergies, be sure to check with your healthcare provider before taking dandelion.
Surgery: Dandelion might slow blood clotting and lower blood sugar. It might cause extra bleeding and problems with low blood sugar during and after surgery. Stop using dandelion at least 2 weeks before a scheduled surgery.
Kidney failure: Dandelion might reduce how much oxalate is released through urine. In theory, this might increase the risk for complications in people with kidney problems.
Antibiotics (Quinolone antibiotics) interacts with DANDELION
Dandelion might decrease how much antibiotic the body absorbs. Taking dandelion along with antibiotics might decrease the effectiveness of some antibiotics.
Some antibiotics that might interact with dandelion include ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), trovafloxacin (Trovan), and grepafloxacin (Raxar).
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with DANDELION
Some medications are changed and broken down by the liver.
Dandelion might decrease how quickly the liver breaks down some medications. Taking dandelion along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking dandelion, talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, others), verapamil (Calan, Isoptin, others), and others.
Medications changed by the liver (Glucuronidated Drugs) interacts with DANDELION
The body breaks down some medications to get rid of them. The liver helps break down these medications. Dandelion might increase how quickly some medications are changed by the liver. This could decrease how well some of these medications work.
Some of these medications changed by the liver include acetaminophen, atorvastatin (Lipitor), diazepam (Valium), digoxin, entacapone (Comtan), estrogen, irinotecan (Camptosar), lamotrigine (Lamictal), lorazepam (Ativan), lovastatin (Mevacor), meprobamate, morphine, oxazepam (Serax), and others.
Water pills (Potassium-sparing diuretics) interacts with DANDELION
Dandelion contains significant amounts of potassium. Some "water pills" can also increase potassium levels in the body. Taking some "water pills" along with dandelion might cause too much potassium to be in the body.
Some "water pills" that increase potassium in the body include amiloride (Midamor), spironolactone (Aldactone), and triamterene (Dyrenium).
Lithium interacts with DANDELION
Dandelion might have an effect like a water pill or "diuretic." Taking dandelion might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.
Be cautious with this combination
Huang, Y., Wu, T., Zeng, L., and Li, S. Chinese medicinal herbs for sore throat. Cochrane Database Syst.Rev 2012;3:CD004877. View abstract.
Ingber, A. Seasonal allergic contact dermatitis from Taraxacum officinale (dandelion) in an Israeli florist. Contact Dermatitis 2000;43(1):49. View abstract.
Kim, H. M., Lee, E. H., Shin, T. Y., Lee, K. N., and Lee, J. S. Taraxacum officinale restores inhibition of nitric oxide production by cadmium in mouse peritoneal macrophages. Immunopharmacol.Immunotoxicol. 1998;20(2):283-297. View abstract.
Kim, H. M., Oh, C. H., and Chung, C. K. Activation of inducible nitric oxide synthase by Taraxacum officinale in mouse peritoneal macrophages. Gen.Pharmacol 1999;32(6):683-688. View abstract.
Koo, H. N., Hong, S. H., Song, B. K., Kim, C. H., Yoo, Y. H., and Kim, H. M. Taraxacum officinale induces cytotoxicity through TNF-alpha and IL-1alpha secretion in Hep G2 cells. Life Sci 1-16-2004;74(9):1149-1157. View abstract.
Liang, K. L., Su, M. C., Shiao, J. Y., Wu, S. H., Li, Y. H., and Jiang, R. S. Role of pollen allergy in Taiwanese patients with allergic rhinitis. J Formos.Med Assoc. 2010;109(12):879-885. View abstract.
Menghini, L., Genovese, S., Epifano, F., Tirillini, B., Ferrante, C., and Leporini, L. Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation. Int J Immunopathol.Pharmacol 2010;23(2):601-610. View abstract.
Ovadje, P., Chatterjee, S., Griffin, C., Tran, C., Hamm, C., and Pandey, S. Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract. J Ethnopharmacol. 1-7-2011;133(1):86-91. View abstract.
Ovadje, P., Chochkeh, M., Akbari-Asl, P., Hamm, C., and Pandey, S. Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells. Pancreas 2012;41(7):1039-1047. View abstract.
Ovadje, P., Hamm, C., and Pandey, S. Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells. PLoS.One. 2012;7(2):e30604. View abstract.
Posadzki, P., Watson, L. K., and Ernst, E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med 2013;13(1):7-12. View abstract.
Rodriguez, B., Rodriguez, A., de Barrio, M., Tornero, P., and Baeza, M. L. Asthma induced by canary food mix. Allergy Asthma Proc. 2003;24(4):265-268. View abstract.
Swanston-Flatt, S. K., Day, C., Flatt, P. R., Gould, B. J., and Bailey, C. J. Glycaemic effects of traditional European plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetes Res 1989;10(2):69-73. View abstract.
Syhaieva, I. A. [Efficiency of specific immunotherapy in treatment of patients with seasonal allergic rhinitis]. Lik.Sprava. 2006;(1-2):51-53. View abstract.
Tan YM, Wang LH Chen SK. Compound Pugongying decoction for acute suppurative tonsillitis. Journal Of An Hui Zhong YI College 2010;29(4):9-12.
Tita B, Bello U, Faccendini P, and et al. Taraxacum officinale W.: pharmacological effect of ethanol extract. Pharmacological Res 1993;27(Suppl 1):23-24.
Wakelin, S. H., Marren, P., Young, E., and Shaw, S. Compositae sensitivity and chronic hand dermatitis in a seven-year-old boy. Br J Dermatol 1997;137(2):289-291. View abstract.
Yang, Y., Zhao, Y., Wang, C. S., Wang, X. D., and Zhang, L. [Prevalence of sensitization to aeroallergens in 10 030 patients with allergic rhinitis]. Zhonghua Er.Bi Yan.Hou Tou.Jing.Wai Ke Za Zhi 2011;46(11):914-920. View abstract.
Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. View abstract.
Baba K, Abe S, Mizuno D. [Antitumor activity of hot water extract of dandelion, Taraxacum officinale-correlation between antitumor activity and timing of administration (author's transl)]. Yakugaku Zasshi 1981;101:538-43. View abstract.
Chakurski I, Matev M, Koichev A, et al. [Treatment of chronic colitis with an herbal combination of Taraxacum officinale, Hipericum perforatum, Melissa officinaliss, Calendula officinalis and Foeniculum vulgare]. Vutr Boles. 1981;20:51-4. View abstract.
Chivato T, Juan F, Montoro A, Laguna R. Anaphylaxis induced by ingestion of a pollen compound. J Investig Allergol Clin Immunol 1996;6:208-9. View abstract.
Cohen SH, Yunginger JW, Rosenberg N, Fink JN. Acute allergic reaction after composite pollen ingestion. J Allergy Clin Immunol 1979;64:270-4. View abstract.
Collier MH, Rogstad SH. Clonal variation in floral stage timing in the common dandelion Taraxacum officinale (Asteraceae). Am J Bot. 2004 Nov;91(11):1828-33. View abstract.
Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. View abstract.
Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
González-Castejón M, Visioli F, Rodriguez-Casado A. Diverse biological activities of dandelion. Nutr Rev. 2012;70(9):534-47. View abstract.
Hu C, Kitts DD. Antioxidant, prooxidant, and cytotoxic activities of solvent-fractionated dandelion (Taraxacum officinale) flower extracts in vitro. J Agric Food Chem 2003;51:301-10. View abstract.
Hu C, Kitts DD. Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro. Phytomedicine 2005;12:588-97. View abstract.
Hu C, Kitts DD. Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells. Mol Cell Biochem 2004;265:107-13. View abstract.
Hussain Z, Waheed A, Qureshi RA, et al. The effect of medicinal plants of Islamabad and Murree region of Pakistan on insulin secretion from INS-1 cells. Phytother Res 2004;18:73-7. View abstract.
Jovanovic M, Mimica-Dukic N, Poljacki M, Boza P. Erythema multiforme due to contact with weeds: a recurrence after patch testing. Contact Dermatitis 2003;48:17-25. View abstract.
Kashiwada Y, Takanaka K, Tsukada H, et al. Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale. J Asian Nat Prod Res 2001;3:191-7. View abstract.
Larsson B, Jonasson A, Fianu S. Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report. Curr Ther Res 1993;53:441-3.
Lovell CR, Rowan M. Dandelion dermatitis. Contact Dermatitis 1991;25:185-8. View abstract.
Luo ZH. [The use of Chinese traditional medicines to improve impaired immune functions in scald mice]. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 1993;9:56-8, 80. View abstract.
Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. View abstract.
Martín-Muñoz MF, Bartolome B, Caminoa M, et al. Bee pollen: a dangerous food for allergic children. Identification of responsible allergens. Allergol Immunopathol (Madr) 2010;38:263-5. View abstract.
Mascolo N, Autore G, Capassa F, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987:28-31.
Moriarty B, Pinney JH, Owen-Casey MP, Rustin MH, Deroide F, Laing C, Davenport A. Digital necrosis from dandelion tea. Br J Dermatol. 2013 Jul;169(1):227-30. View abstract.
Neef H, Cilli F, Declerck PJ, et al. Platelet anti-aggregating activity of Taraxacum officinale Weber. Phytotherapy Research 1996;10:s138-s140.
Onal S, Timur S, Okutucu B, Zihnioglu F. Inhibition of alphaglucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. Prep Biochem Biotechnol 2005;35:29-36. View abstract.
Fernandez-Gonzalez, D., Gonzalez-Parrado, Z., Vega-Maray, A. M., Valencia-Barrera, R. M., Camazon-Izquierdo, B., De, Nuntiis P., and Mandrioli, P. Platanus pollen allergen, Pla a 1: quantification in the atmosphere and influence on a sensitizing population. Clin Exp Allergy 2010;40(11):1701-1708. View abstract.
Goksu, E., Eken, C., Karadeniz, O., and Kucukyilmaz, O. First report of hypoglycemia secondary to dandelion (Taraxacum officinale) ingestion. Am J Emerg.Med 2010;28(1):111-112. View abstract.
Hagymasi, K., Blazovics, A., Feher, J., Lugasi, A., Kristo, S. T., and Kery, A. The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation. Phytother Res 2000;14(1):43-44. View abstract.
Han, H., He, W., Wang, W., and Gao, B. Inhibitory effect of aqueous Dandelion extract on HIV-1 replication and reverse transcriptase activity. BMC.Complement Altern.Med 2011;11:112. View abstract.
Hata, K., Ishikawa, K., Hori, K., and Konishi, T. Differentiation-inducing activity of lupeol, a lupane-type triterpene from Chinese dandelion root (Hokouei-kon), on a mouse melanoma cell line. Biol Pharm Bull 2000;23(8):962-967. View abstract.
He, W., Han, H., Wang, W., and Gao, B. Anti-influenza virus effect of aqueous extracts from dandelion. Virol.J 2011;8:538. View abstract.
Hook I, McGee A, Henman M, and et al. Evaluation of dandelion for diuretic activity and variation in potassium content. Int J Pharmacog 1993;31(1):29-34.
Akhtar, M. S., Khan, Q. M., and Khaliq, T. Effects of Portulaca oleracae (Kulfa) and Taraxacum officinale (Dhudhal) in normoglycaemic and alloxan-treated hyperglycaemic rabbits. J Pak.Med Assoc 1985;35(7):207-210. View abstract.
Bohm K. Studies on the choleretic action of some drugs. Azneim-Forsh 1959;9:376-378.
Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. View abstract.
Chen, Z. [Clinical study of 96 cases with chronic hepatitis B treated with jiedu yanggan gao by a double-blind method]. Zhong.Xi.Yi.Jie.He.Za Zhi. 1990;10(2):71-4, 67. View abstract.
Clare, B. A., Conroy, R. S., and Spelman, K. The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day. J Altern.Complement Med 2009;15(8):929-934. View abstract.
Collins JM and Miller DR. Dandelion green bezoar following antrectomy and vagotomy - case report. J Kansas Med Soc 1966;67(6):303-304. View abstract.
Davies, M. G. and Kersey, P. J. Contact allergy to yarrow and dandelion. Contact Dermatitis 1986;14(4):256-257. View abstract.
Racz-Kotilla E, Racz G, Solomon A. The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med 1974;26:212-7. View abstract.
Rasmussen A, Jacob SE. Dandelion: An important allergen in atopic children. Dermatitis. 2017r;28(2):166. View abstract.
Rodriguez-Fragoso L, Reyes-Esparza J, Burchiel SW, Herrera-Ruiz D, Torres E. Risks and benefits of commonly used herbal medicines in Mexico. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):125-35. View abstract.
Seo SW, Koo HN, An HJ, et al. Taraxacum officinale protects against cholecystokinin-induced acute pancreatitis in rats. World J Gastroenterol 2005;11:597-9. View abstract.
Tan YM, Wang LH, Chen SK. Compound Pugongying decoction for acute suppurative tonsillitis. Journal Of An Hui Zhong YI College 2010;29:9-12.
Trojanova I, Rada V, Kokoska L, Vlkova E. The bifidogenic effect of Taraxacum officinale root. Fitoterapia 2004;75:760-3. View abstract.
Williams CA, Goldstone F, Greenham J. Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry 1996;42:121-7. View abstract.
Yousefi Ghale-Salimi M, Eidi M, Ghaemi N, Khavari-Nejad RA. Antiurolithiatic effect of the taraxasterol on ethylene glycol induced kidney calculi in male rats. Urolithiasis. 2018;46(5):419-428. View abstract.
Yousefi Ghale-Salimi M, Eidi M, Ghaemi N, Khavari-Nejad RA. Inhibitory effects of taraxasterol and aqueous extract of Taraxacum officinale on calcium oxalate crystallization: in vitro study. Ren Fail. 2018;40(1):298-305. View abstract.
Zhu M, Wong PY, Li RC. Effects of taraxacum mongolicum on the bioavailability and disposition of ciprofloxacin in rats. J Pharm Sci 1999;88:632-4. View abstract.
You Might Also Like
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.