Despite serious safety concerns, coltsfoot is used for asthma, cough, sore throat, swelling of the airways, and other conditions, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness
Insufficient Evidence for
When inhaled: There isn't enough reliable information to know if coltsfoot is safe when inhaled or what the side effects might be.
Special Precautions and Warnings
When inhaled: There isn't enough reliable information to know if coltsfoot is safe when inhaled or what the side effects might be. Coltsfoot is considered LIKELY UNSAFE for anyone, but people with the following conditions should be especially careful about avoiding this plant:
Pregnancy and breast-feeding: Coltsfoot preparations are LIKELY UNSAFE for use during pregnancy or breast-feeding. Coltsfoot contains chemicals called hepatotoxic pyrrolizidine alkaloids (PAs). These chemicals might cause birth defects and liver or lung damage. Even if the product is certified hepatotoxic PA-free, it's best to avoid use.
Allergy to ragweed and related plants: Coltsfoot may cause an allergic reaction in people who are allergic to the Asteraceae/Compositae plant family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking coltsfoot.
High blood pressure, heart disease: There is a concern that coltsfoot taken in large amounts might interfere with treatment for these conditions. Don't use coltsfoot if you have these conditions.
Liver disease: There is a concern that hepatotoxic PAs might make liver disease worse. Don't use coltsfoot if you have this condition.
Medications for high blood pressure (Antihypertensive drugs) interacts with COLTSFOOT
Excessive doses of coltsfoot seem to increase blood pressure. By increasing blood pressure coltsfoot might decrease the effectiveness of medications for high blood pressure.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Medications that increase break down of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with COLTSFOOT
Coltsfoot is broken down by the liver. Some chemicals that form when the liver breaks down coltsfoot can be harmful. Medications that cause the liver to break down coltsfoot might increase the toxic effects of chemicals contained in coltsfoot.
Some of these medicines include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with COLTSFOOT
Coltsfoot might slow blood clotting. Taking coltsfoot along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Be cautious with this combination
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.