Despite serious safety concerns, calotropis is used for digestive disorders including diarrhea, constipation and stomach ulcers; for painful conditions including toothache, cramps, and joint pain; and for parasitic infections including elephantiasis and worms. Some people use calotropis for syphilis, boils, inflammation (swelling), epilepsy, hysteria, fever, muscular spasm, warts, leprosy, gout, snakebites, and cancer.
In inhalation therapy, smoke from the bark is inhaled for coughs, asthma, and to cause sweating.
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