People use GLA for conditions such as nerve pain in people with diabetes (diabetic neuropathy), eczema (atopic dermatitis), arthritis, high blood pressure, and other conditions, but there is no good scientific evidence to support most of these uses.
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
Possibly Ineffective for
- Eczema (atopic dermatitis). Most research shows that taking GLA by mouth does not improve itchy or dry skin in people with eczema.
- Hardening of skin and connective tissue (scleroderma). Taking GLA by mouth does not seem to reduce symptoms of scleroderma.
- A type of inflammatory bowel disease (ulcerative colitis). Taking GLA plus eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by mouth does not reduce symptoms of ulcerative colitis.
Special Precautions and Warnings
Bleeding disorders: GLA might slow blood clotting. There is some concern that it might increase the risk of bruising and bleeding in people with bleeding disorders.
Surgery: Since GLA might slow blood clotting, there is concern that it might increase the risk of extra bleeding during and after surgery. Stop taking gamma linolenic acid at least 2 weeks before a scheduled surgery.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GAMMA-LINOLENIC ACID (GLA)
GLA might slow blood clotting. Taking GLA along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Phenothiazines interacts with GAMMA-LINOLENIC ACID (GLA)
Taking GLA with phenothiazines might increase the risk of having a seizure in some people.
Some phenothiazines include chlorpromazine (Thorazine), fluphenazine (Prolixin), trifluoperazine (Stelazine), thioridazine (Mellaril), and others.
Be cautious with this combination
- For nerve pain in people with diabetes (diabetic neuropathy): 360 to 480 mg of GLA per day has been used.
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