Thunder god vine (Tripterygium wilfordii) is a vine that grows in southeast China. Its extracts are used in traditional and pharmaceutical Chinese medicine.

Thunder god vine contains chemicals that might relieve swelling and change the way the immune system works. This might help with arthritis and other conditions. Also, thunder god vine contains chemicals that might alter sperm and decrease male fertility.

People use thunder god vine for rheumatoid arthritis (RA), Crohn disease, kidney problems, mouth sores, and eye problems in people with an overactive thyroid. It is also used for eczema, birth control, menstrual cramps, and many other conditions, but there is no good scientific evidence to support many of these uses.

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