Bromelain is used for pain, muscle soreness, burns, and many other conditions, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness ?
Possibly Ineffective for
Insufficient Evidence for
- Burns. Early research shows that applying gel containing bromelain enzymes under a wound dressing helps remove dead tissue from burns.
- Kidney stones. Early research found that adding bromelain to tamsulosin might help the body get rid of kidney stones.
- Knee pain. Early research shows that taking bromelain by mouth might reduce mild knee pain.
- Osteoarthritis. Early research shows that taking bromelain by mouth alone doesn't seem to help arthritis pain.
- A skin condition that causes small, scaling, raised spots (pityriasis lichenoides chronica or PLC). Early research shows that bromelain might help treat episodes of PLC.
- Pain after surgery. Some research shows that bromelain slightly reduces pain after removal of wisdom teeth. But it doesn't seem to reduce lockjaw or swelling.
- Swelling (inflammation) of the nasal cavity and sinuses (rhinosinusitis). Early research shows that taking bromelain along with decongestants, antihistamines, or antibiotics helps reduce nasal swelling in people with sinusitis. But this research is not very reliable.
- Nerve damage in the hands and feet caused by cancer drug treatment.
- Acute pain.
- Hay fever.
- Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs).
- Painful conditions caused by overuse of tendons (tendinopathy).
- Swelling in the arms or legs caused by damage to the lymph system (lymphedema).
- Other conditions.
When applied to the skin: Bromelain is POSSIBLY SAFE for most people when applied to the skin in appropriate amounts.
Special Precautions and Warnings
Allergies: You might have an allergic reaction to bromelain if you are allergic to pineapple, latex, ragweed, Echinacea, chrysanthemums, marigolds, daisies, wheat, celery, papain, carrot, fennel, cypress pollen, grass pollen, or other plants.
Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.
Amoxicillin (Amoxil, Trimox) interacts with BROMELAIN
Taking bromelain might increase how much amoxicillin is in the body. Taking bromelain along with amoxicillin might increase effects and side effects of amoxicillin.
Antibiotics (Tetracycline antibiotics) interacts with BROMELAIN
Taking bromelain might increase how much antibiotic the body absorbs. Taking bromelain along with some antibiotics might increase effects and side effects of some antibiotics called tetracyclines.
Some tetracyclines include demeclocycline (Declomycin), minocycline (Minocin), and tetracycline (Achromycin).
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with BROMELAIN
Bromelain might slow blood clotting. Taking bromelain along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Be cautious with this combination
- For osteoarthritis: a combination product (Phlogenzym), which contains rutin 100 mg, trypsin 48 mg, and bromelain 90 mg, given as 2 tablets 3 times daily has been used.
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