BLESSED THISTLE
Carbenia Benedicta, Cardo Bendito, Cardo Santo, Carduus, Carduus Benedictus, Chardon Béni, Chardon Bénit, Chardon Marbré, Cnici Benedicti Herba, Cnicus, Cnicus benedictus, Holy Thistle, Safran Sauvage, Spotted Thistle, St. Benedict Thistle.
Uses & Effectiveness
Insufficient Evidence for
- Diarrhea.
- Cancer.
- Coughs.
- Infections.
- Boils.
- Wounds.
- Promoting milk flow in breast-feeding mothers.
- Promoting urine flow.
- Other conditions.
Side Effects & Safety
Blessed thistle is LIKELY SAFE when used in amounts commonly food in foods. There is not enough information available to know if blessed thistle is safe in medicine amounts. In high doses, such as more than 5 grams per cup of tea, blessed thistle can cause stomach irritation and vomiting.Special Precautions & Warnings:
Pregnancy and breast-feeding: Don't take blessed thistle by mouth if you are pregnant. There is some evidence that it might not be safe during pregnancy. It's also best to avoid blessed thistle if you are breast-feeding. Not enough is known about the safety of this product.Intestinal problems, such as infections, Crohn's disease, and other inflammatory conditions: Don't take blessed thistle if you have any of these conditions. It might irritate the stomach and intestines.
Allergy to ragweed and related plants: Blessed thistle may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking blessed thistle.
Interactions
Minor Interaction
Be watchful with this combination
-
Antacids interacts with BLESSED THISTLE
Antacids are used to decrease stomach acid. Blessed thistle may increase stomach acid. By increasing stomach acid, blessed thistle might decrease the effectiveness of antacids.
Some antacids include calcium carbonate (Tums, others) dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), magnesium sulfate (Bilagog), aluminum hydroxide (Amphojel), and others. -
Medications that decrease stomach acid (H2-Blockers) interacts with BLESSED THISTLE
Blessed thistle might increase stomach acid. By increasing stomach acid, blessed thistle might decrease the effectiveness of some medications that decrease stomach acid, called H2-Blockers.
Some medications that decrease stomach acid include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid). -
Medications that decrease stomach acid (Proton pump inhibitors) interacts with BLESSED THISTLE
Blessed thistle might increase stomach acid. By increasing stomach acid, blessed thistle might decrease the effectiveness of medications that are used to decrease stomach acid, called proton pump inhibitors.
Some medications that decrease stomach acid include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).
Dosing
The appropriate dose of blessed thistle depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for blessed thistle. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
REFERENCES:
- Pfeiffer K, Trumm S, Eich E, and et al. HIV-1 integrase as a target for anti-HIV drugs. Arch STD/HIV Res 1999;6:27-33.
- Recio M, Rios J, and Villar A. Antimicrobial activity of selected plants employed in the Spanish Mediterranean area. Part II. Phytother Res 1989;3:77-80.
- Ryu SY, Ahn JW, Kang YH, and et al. Antiproliferative effect of arctigenin and arctiin. Arch Pharm Res 1995;18(6):462-463.
- Schneider, G. and Lachner, I. [Analysis and action of cnicin]. Planta Med 1987;53(3):247-251. View abstract.
- Vanhaelen M and Vanhaelen-Fastre R. Lactonic lignans from Cnicus benedictus. Phytochemistry 1975;14:2709.
- Perez, C. and Anesini, C. In vitro antibacterial activity of Argentine folk medicinal plants against Salmonella typhi. J Ethnopharmacol 1994;44(1):41-46. View abstract.
- Perez C and Anesini C. Inhibition of Pseudomonas aeruginosa by Argentinean medicinal plants. Fitoterapia 1994;65(2):169-172.
- Nose, M., Fujimoto, T., Nishibe, S., and Ogihara, Y. Structural transformation of lignan compounds in rat gastrointestinal tract; II. Serum concentration of lignans and their metabolites. Planta Med 1993;59(2):131-134. View abstract.
- Barrero, A. F., Oltra, J. E., Morales, V., Alvarez, M., and Rodriguez-Garcia, I. Biomimetic cyclization of cnicin to malacitanolide, a cytotoxic eudesmanolide from Centaurea malacitana. J Nat Prod. 1997;60(10):1034-1035. View abstract.
- Cobb E. Antineoplastic agent from Cnicus benedictus. Patent Brit 1973;335:181.
- Duke JA. Green Pharmacy. Emmaus, PA: Rodale Press;1997:507.
- Eich, E., Pertz, H., Kaloga, M., Schulz, J., Fesen, M. R., Mazumder, A., and Pommier, Y. (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase. J Med Chem 1-5-1996;39(1):86-95. View abstract.
- Hirano, T., Gotoh, M., and Oka, K. Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Life Sci 1994;55(13):1061-1069. View abstract.
- Kataria H. Phytochemical investigation of medicinal plant Cnicus wallichii and Cnicus benedictus L. Asian J Chem 1995;7:227-228.
- May, G. and Willuhn, G. [Antiviral effect of aqueous plant extracts in tissue culture]. Arzneimittelforschung 1978;28(1):1-7. View abstract.
- Vanhaelen-Fastre R. [Polyacetylen compounds from Cnicus benedictus]. Planta Medica 1974;25:47-59.
- Vanhaelen-Fastre, R. [Antibiotic and cytotoxic activity of cnicin isolated from Cnicus benedictus L]. J Pharm Belg. 1972;27(6):683-688. View abstract.
- Vanhaelen-Fastre, R. [Constitution and antibiotical properties of the essential oil of Cnicus benedictus (author's transl)]. Planta Med 1973;24(2):165-175. View abstract.
- Vanhaelen-Fastre, R. and Vanhaelen, M. [Antibiotic and cytotoxic activity of cnicin and of its hydrolysis products. Chemical structure - biological activity relationship (author's transl)]. Planta Med 1976;29(2):179-189. View abstract.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Mascolo N, Autore G, Capassa F, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987:28-31.
- Paun G, Neagu E, Albu C, et al. Inhibitory potential of some Romanian medicinal plants against enzymes linked to neurodegenerative diseases and their antioxidant activity. Pharmacogn Mag. 2015;11(Suppl 1):S110-6. View abstract.
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