ADRENAL EXTRACT

OTHER NAME(S):

ACE, Adrenal, Adrenal Complex, Adrenal Concentrate, Adrenal Cortex, Adrenal Cortex Extract, Adrenal Factors, Adrenal Medulla, Adrenal Polypeptide Fractions, Adrenal Powder, Adrenal Substance, Cortex Surrénalien, Extracto Suprarrenal, Extrait de Cortex Surrénalien, Extrait de Glandes Surrénales, Extrait de Glandes Surrénales Entières, Facteurs Surrénaliens, Glandulaire,Glandular, Lyophilized Adrenal Tissue, Médullaire des Glandes Surrénales, Médullaire Surrénale, Médullosurrénale, Substance Surrénalienne, Tissu Lyophilisé de Glande Surrénale, Whole Adrenal Extract.<br/><br/>

Overview

Overview Information

Adrenal extract is a chemical that is made from the adrenal glands of slaughtered cows, pigs, and sheep. Adrenal glands make certain hormones. People use the extract as a medicine. It can be taken by mouth, placed under the tongue (used sublingually) or injected into the veins (given intravenously).

By mouth, adrenal extract is used for low adrenal function, fatigue, stress, lowered resistance to illness, severe allergies, asthma, certain skin conditions such as eczema and psoriasis, and rheumatoid arthritis.

Some people put adrenal extract under the tongue for physical or emotional stress, poor stress tolerance, general fatigue, allergies, autoimmune disorders, depression, pain and swelling (inflammation), low blood pressure, low blood sugar, drug and alcohol withdrawal, and discontinuation of cortisone drugs.

Intravenously, adrenal extract has been used for treating low adrenal function, high levels of potassium in the blood, and ulcerative colitis, and for preventing miscarriage.

How does it work?

The adrenal glands sit on top of the kidneys. They regulate the body’s response to stress by making hormones, including adrenaline and cortisol. People use adrenal extract taken from animals in the hope that the extract will function like the body’s adrenal gland. But it’s not known whether the human body can absorb adrenal extract or how it might work.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Low adrenal function.
  • Fatigue.
  • Stress.
  • Fighting off illness.
  • Allergies.
  • Asthma.
  • Skin conditions such as eczema and psoriasis.
  • Rheumatoid arthritis (RA).
  • Depression.
  • Low blood pressure.
  • Low blood sugar.
  • Drug and alcohol withdrawal.
  • Other conditions.
More evidence is needed to rate the effectiveness of adrenal extract for these uses.

Side Effects

Side Effects & Safety

Adrenal extract is UNSAFE when injected. There have been at least 50 reports of serious infection at the injection site.

There isn’t enough information available about the safety of adrenal extract when taken by mouth. But, there are serious concerns. Adrenal extract is made from adrenal glands gathered from slaughterhouses, and possibly from sick or diseased animals. Do not use adrenal extract from countries where a condition known as bovine spongiform encephalitis (BSE) has been reported, more commonly known as "mad cow disease." Countries where BSE has been reported include Great Britain, France, the Netherlands, Portugal, Luxembourg, Ireland, Switzerland, Oman, Belgium, and others. If you can't tell if the adrenal extract is from a country without BSE, don't use it.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of adrenal extract during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Low immune system function: If your body is not able to fight disease normally because of low immune system function (for example, you have HIV/AIDS or you are taking medicines to prevent your body from rejecting an organ transplant) you might be more likely than other people to become infected if you take adrenal extract.

Interactions

Interactions?

We currently have no information for ADRENAL EXTRACT Interactions.

Dosing

Dosing

The appropriate dose of adrenal extract depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for adrenal extract. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Fujii, Y., Kato, N., Kito, J., Asai, J., and Yokochi, T. Experimental autoimmune adrenalitis: a murine model for Addison's disease. Autoimmunity 1992;12(1):47-52. View abstract.
  • GRUNDY, H. M., SIMPSON, S. A., and TAIT, J. F. Isolation of a highly active mineralocorticoid from beef adrenal extract. Nature 5-10-1952;169(4306):795-796. View abstract.
  • MASON, H. L. and MATTOX, V. R. Chromatographic fraction of beef adrenal extract. I. Isolation of aldosterone. J Biol Chem. 1956;223(1):215-225. View abstract.
  • MATTOX, V. R. Isolation of 19-hydroxy-11-desoxycorticosterone from beef adrenal extract. Mayo Clin Proc 5-4-1955;30(9):180-182. View abstract.
  • MATTOX, V. R., MASON, H. L., and ALBERT, A. Isolation of a sodium-retaining substance from beef adrenal extract. Mayo Clin Proc 10-7-1953;28(20):569-576. View abstract.
  • Nagao, Y. Viability of meiotic prophase spermatocytes of rats is facilitated in primary culture of dispersed testicular cells on collagen gel by supplementing epinephrine or norepinephrine: evidence that meiotic prophase spermatocytes complete meiotic divisions in vitro. In Vitro Cell Dev.Biol 1989;25(12):1088-1098. View abstract.
  • Schreiber, V., Stepan, J., Gregorova, I., and Krejcikova, J. Crossed digoxin immunoreactivity in chromatographic fractions of rat adrenal extract. Biochem.Pharmacol 4-1-1981;30(7):805-806. View abstract.
  • Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  • Nationwide alert on hallmark labs injectable adrenal cortex extract. FDA. Available at: www.fda.gov/bbs/topics/NEWS/NEW00539.html

More Resources for ADRENAL EXTRACT

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.