Overview

Gamma hydroxybutyrate (GHB) is a chemical found in the brain and other areas of the body. It can also be made in a laboratory.

GHB used to be available as a dietary supplement in the U.S., but it was taken off the market in 1990 because of safety concerns. It is now a Schedule I controlled substance, making it illegal to produce, sell, or possess. A prescription form of GHB called sodium oxybate (Xyrem) is still available for treating excessive daytime sleepiness (narcolepsy). It is a Schedule III controlled substance, which means that it requires a prescription and close monitoring by a medical doctor.

The prescription form of GHB is used for excessive daytime sleepiness (narcolepsy). It has also been used for alcohol use disorder and opioid withdrawal.

How does it work ?

GHB acts on several nerve pathways in the brain.

View References

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.