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Diabetic Nephropathy - Exams and Tests

Diabetic nephropathy is diagnosed using tests that check for a protein (albumin) in the urine, which points to kidney damage. Your urine will be checked for protein (urinalysis) when you are diagnosed with diabetes.

An albumin urine test can detect very small amounts of protein in the urine that cannot be detected by a routine urine test, allowing early detection of nephropathy. Early detection is important, to prevent further damage to the kidneys. The results of two tests, done within a 3- to 6-month period, are needed to diagnose nephropathy.

When to begin checking for protein in the urine depends on the type of diabetes you have. After testing begins, it should be done every year.1

Albumin testing
Type of diabetes When to begin yearly testing

Type 1 diabetes

After you have had diabetes for 5 years

Type 2 diabetes

When you are diagnosed with diabetes

Diabetes present during childhood

After age 10 and after the child has had diabetes for 5 years

An albuminuria dipstick test is a simple test that can detect small amounts of protein in the urine. The strip changes color if protein is present, providing an estimate of the amount of protein. A spot urine test for albuminuria is a more precise lab test that can measure the exact amount of protein in a urine sample. Either of these tests may be used to test your urine for protein.

You will also have a creatinine test done every year. The creatinine test is a blood test that shows how well your kidneys are working.

If your doctor suspects that the protein in your urine may be caused by a disease other than diabetes, other blood and urine tests may be done. You may have a small sample of kidney tissue removed and examined (kidney biopsy).

Other tests

It is important to check your blood pressure regularly, both at home and in your doctor's office, because blood pressure rises as kidney damage progresses. For most people who have diabetes, the ideal blood pressure is below 120/80. High blood pressure is 140/80 or higher when you have diabetes. In between these two levels is called prehypertension. Keeping your blood pressure at or below your target can prevent or slow kidney damage.

Blood levels of cholesterol and triglycerides also should be checked regularly to see whether diabetes, nephrotic syndrome, or other factors are raising your blood cholesterol level. High cholesterol can increase the risk of hardening of the arteries (atherosclerosis), possibly leading to heart disease, peripheral arterial disease, and stroke.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: January 28, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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