Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
The cause of the interaction is not known. NSAIDs may increase the effects of your blood thinner. NSAIDs may also have blood thinning effects.
What might happen:
The effect of your blood thinner may increase.You may experience an increased chance for bleeding including bleeding from your gums, nosebleeds, unusual bruising, or dark stools.
What you should do about this interaction:
This interaction is most likely to occur when starting, stopping or changing the dose of your NSAID. If your doctor prescribes these two medicines together, you may need to have your bleeding times checked more often. It may be necessary to adjust the dose of your blood thinner. This dose adjustment will be more complicated if you use your NSAID only when needed and not every day.If you experience bruising or bleeding, contact your doctor. Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. Do not stop, start, or change the dosage of any medicine before checking with them first.
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