Osteoporosis Drug a Better HRT?
Evista Offers Promise of Disease Prevention for Older Women
Could Provide 'Widespread' Protection continued...
So is Evista the disease-prevention panacea for older women that the hormone replacement therapy Prempro was once thought to be? All agree that it is way too early to say. While Evista does not appear to promote endometrial cancer like tamoxifen does, its use is associated with a small risk in blood clots in the leg. And it can actually worsen hot flashes in menopausal women, especially in those closest to the onset on menopause.
"We thought we had a good preventive drug with hormone replacement therapy, but we now know that this is not true," Jordan tells WebMD. "Tamoxifen is good for the treatment of breast cancer, but it doesn't have the right safety profile to give to everyone. The hope is that Evista has a better safety profile and protects against heart attack, bone loss, and breast cancer."