Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Heart Disease Health Center

Font Size

Ibuprofen, Naproxen: No Heart Risk

Pain Relievers Don't Increase Risk of Heart Attacks, Study Shows

Measuring NSAID Risk continued...

Although the overall longer use (over a year) of all traditional NSAIDs was associated with a 20% increase in the risk for nonfatal heart attacks, the longer use of ibuprofen specifically appeared to have no impact on risk.

Use of diclofenac demonstrated a small increased risk for heart attack with longer use.

Use of naproxen for longer than a year was associated with a slight decrease in heart attack risk, but it was not clear if the association was real.

"Our study suggests either no effect or a small reduction of cardiovascular risk during sustained treatment with naproxen, a small increased risk with diclofenac, and an undetectable risk with ibuprofen," Garcia Rodriguez and Gonzalez-Perez wrote.

Ask Your Doctor

The new findings may help to allay the fears of regular ibuprofen or naproxen users. But American Heart Association (AHA) spokesman David Herrington, MD, MHS, says patients should still discuss the long-term use of these drugs with their doctor.

The Wake Forest University cardiology professor co-authored a recent AHA advisory on the use of pain medications.

"We said that people should try to use the simplest and safest medications first in the recommended dosages for the shortest possible period of time," he tells WebMD.

For most people that means aspirin or acetaminophen (Tylenol), which have the longest and most well-established safety records, he adds.

Ibuprofen, naproxen, and other NSAIDs should be used for chronic pain under a doctor's supervision by people who can't take aspirin or acetaminophen or by those who do not get adequate pain relief with the drugs, the AHA recommends.

"Every treatment decision is a balance of safety and efficacy, and this is certainly no different," Herrington says. "People shouldn't suffer unnecessarily, but it is important that people who take these drugs long term get guidance from a physician."

1 | 2

Today on WebMD

x-ray of human heart
A visual guide.
atrial fibrillation
Symptoms and causes.
heart rate graph
10 things to never do.
heart rate
Get the facts.
empty football helmet
red wine
eating blueberries
Simple Steps to Lower Cholesterol
Inside A Heart Attack
Omega 3 Sources
Salt Shockers
lowering blood pressure