Many people with irritable bowel syndrome (IBS) turn to laxatives to relieve constipation, but laxatives usually offer limited help.
Although laxatives do ease constipation, there's no proof that they relieve stomach aches, bloating, and discomfort that come with IBS. That's because the drugs have never been thoroughly studied for the treatment of IBS in randomized controlled trials. In these trials, people are randomly assigned to different treatments without knowing which one they receive. Researchers...
Rifaximin (Xifaxan), which has been shown to help people who have diarrhea and bloating as their worst symptoms. In one study, people who had fewer symptoms after 2 weeks of taking rifaximin continued to have fewer symptoms for 10 weeks after stopping the medicine. But rifaximin is very expensive, and more research needs to be done. There are still many questions about this treatment, including who will get the most benefit, how long the effect will last, and whether retreatment will work when symptoms come back.5
Alosetron (Lotronex), which is used for some women who have severe diarrhea. This medicine has been shown to contribute to ischemic bowel disease. Specific guidelines for the use of alosetron require doctors who prescribe it to sign a certificate and patients to sign a consent form.
There are many medicines for severe constipation that doesn't improve with home treatment. Most of these medicines are available without a prescription and are okay to take once in a while. Check with your doctor before you use any of these medicines every day for constipation. Medicines for constipation include: