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Alcohol Damages the Teen-age Brain


WebMD Health News

June 2, 2000 -- Researchers have just come up with another reason to warn teen-agers not to drink alcohol: Specialized brain imaging studies have shown that teens and young adults, who drank heavily over long periods of time, showed shrinkage of an area of the brain that is responsible for memory and learning. This shrinkage was not seen in teens who did not drink.

The risk of this type of damage is greatest in those who begin drinking at a younger age and those who drink for longer periods of time, according to the study.

"Only in recent years have we known the extent of brain development during adolescence," says co-author of the study, Duncan B. Clark, MD, PhD. "The hippocampus is one of the areas that's rapidly changing at this time and may be particularly affected by alcohol."

But Clark also suggests that the toxic effects of alcohol on the brain might be reversible, especially if the alcohol use is discontinued early.

Susan F. Tapert, PhD, a research scientist with the Veterans Medical Research Foundation and the University of California at San Diego, reviewed the study for WebMD. "We still need more studies, but it looks like there's a good possibility that drinking heavily during the teen-age years could affect your ability to remember things and learn new things," she says. "If you want to do well in school and be able to remember all kinds of things that you learn, it's best to avoid any kind of heavy drinking."

Many people may be surprised to learn that the brain is still developing during the teen years. "Adolescence is a period during which we now know the brain continues to rapidly develop," Clark says. "We know that alcohol can damage the brain. Adolescent alcohol abuse and dependence may have a damaging effect on adolescent brain development, and it is possible that these effects have lifelong adverse consequences.

"The effects of alcohol problems on adolescent brain development have not received much attention, in part because the technology for examining the brain has only recently been developed to the point where we can see the small differences we would expect in the adolescent period. ... This technology [for seeing the brain] provides us with a method for examining areas of the brain that may be affected by alcohol," says Clark, who is director of the Pittsburgh Adolescent Alcohol Research Center.

In this report in the June issue of the American Journal of Psychiatry, a special brain scan, called an MRI, was used to measure differences in the sizes of various brain regions in 12 adolescents and young adults who used alcohol excessively, and 24 healthy youngsters who had no drinking problems.

The researchers focused on measuring the size of an area of the brain, the hippocampus, which is known to be sensitive to the effects of alcohol in adults. The hippocampus is associated with learning and memory functions, Clark says. Two hippocampi are found in the brain, one on the right side and the other on the left side.

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