PREVIOUS QUESTION:

 

NEXT QUESTION:

 

What are monoamine oxidase inhibitors (MAOIs)?

ANSWER

Monoamine oxidase inhibitors are a very powerful class of antidepressants. They prevent the breakdown of serotonin, dopamine, and norepinephrine in the brain and raise their levels. These drugs are not used often because they can interact with other medications and cause problems with blood pressure and other complications. People who take them also need to avoid certain foods. MAOIs also can be dangerous in case of an overdose. These drugs are usually prescribed for bipolar depression only in combination with a mood stabilizer such as lithium or valproate in order to lower the chances of triggering a mania.

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)."  WebMD Assess Plus: Bipolar Disorder Assessment.  National Institute of Mental Health: "Step-BD Womens Studies."  Massachusetts General Hospital Bipolar Clinic & Research Program.  MedicineNet: "Bipolar Disorder (Mania)."  WebMD Medical Reference: "Effects of Untreated Depression."  American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on July 12, 2018

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)."  WebMD Assess Plus: Bipolar Disorder Assessment.  National Institute of Mental Health: "Step-BD Womens Studies."  Massachusetts General Hospital Bipolar Clinic & Research Program.  MedicineNet: "Bipolar Disorder (Mania)."  WebMD Medical Reference: "Effects of Untreated Depression."  American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Smitha Bhandari on July 12, 2018

NEXT QUESTION:

What monoamine oxidase inhibitors (MAOIs) can be used for bipolar depression?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.