MEDROXYPROGESTERONE ACETATE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

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    If experienced, these tend to have a Less Severe expression i

    • altered interest in having sexual intercourse
    • abnormal bleeding from the uterus
    • a problem with menstrual periods
    • dizziness
    • weight gain
    • headache
    • nervousness
    • reactions at the site of the injection

    INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

    • depression

    If experienced, these tend to have a Less Severe expression i

    • urinary tract infection
    • breast pain
    • inflammation or infection of the vagina
    • vaginal discharge
    • pain with menstruation
    • hair loss
    • acne
    • joint pain
    • leg cramps
    • difficulty sleeping
    • low energy
    • visible water retention
    • nausea
    • abdominal bloating
    • generalized weakness
    • discharge of fluid from the cervix
    • drug-induced hot flashes

    RARE side effects

    If experienced, these tend to have a Severe expression i

    • a breast tumor
    • a hormone disorder where the body produces high levels of cortisol called Cushing's syndrome
    • high amount of calcium in the blood
    • anemia
    • a clot in the small veins that carry blood to or from the retina of the eye
    • optic disk edema
    • a clot in the lung
    • obstruction of a blood vessel by a blood clot
    • a blood clot in an artery
    • thrombophlebitis, an inflamed vein due to a blood clot
    • blood clot in a deep vein of the extremities
    • blood coming from anus
    • a blockage of the bile duct that resulting in high bilirubin levels
    • breastmilk production not associated with childbirth or nursing
    • overgrowth of the uterine lining
    • erythema multiforme, a type of allergic skin reaction
    • erythema nodosum, a skin condition with red and painful nodules
    • scleroderma, hardening and tightening of the skin and connective tissues
    • osteoporosis, a condition of weak bones
    • decreased calcification or density of bone
    • seizures
    • a broken bone
    • a significant type of allergic reaction called anaphylaxis
    • a type of allergic reaction called angioedema
    • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
    • paralysis of nerves for the face
    • squamous cell carcinoma of cervix

    If experienced, these tend to have a Less Severe expression i

    • an extreme sense of wellbeing called euphoria
    • enlarged superficial veins
    • absence of menstrual periods
    • a decrease in production of breast milk
    • itching
    • hirsutism, a condition of hair growth on parts of the body normally without hair
    • dry skin
    • hives
    • yellow-brown patches on skin
    • drowsiness
    • fever
    • body odor
    • excessive thirst
    • changes in appetite
    • hoarseness
    • abnormal glucose tolerance test results
    • a feeling of pins and needles on skin
    • a feeling of general discomfort called malaise
    • abnormal fat distribution
    • a fibrous thickening of the skin called induration
    • an increased interest in having sexual intercourse
    • pain with sexual intercourse

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.