What should I Know Regarding Pregnancy, Nursing and Administering Clozapine to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: Neuro/Psych-Generally not recommended. Higher risk of tardive dyskinesia. May cause sedation, worsen cognitive impairment. Increased fall risk. Increased risk of death in senile dementia Cardiovascular-Risk of orthostatic hypotension & tachycardia. Cardiovascular & cerebrovascular risks may increase with metabolic changes Gastrointestinal-Significant constipation risk including complete bowel blockage. Consider adding prophylactic bowel regimen Genitourinary-Urinary retention risk
  • Pediatric use

  • Severe Precaution: Risk of severe neutropenia, seizure, cardiomyopathy, orthostatic hypotension, respiratory arrest. Safety and efficacy not established.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.