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What are the side effects of Depo-Provera?

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They can include:

Changes in the menstrual cycle is the most common side effect. You may have irregular bleeding or spotting. After a year of use, about 50% of women will stop getting their periods. Their periods usually return when they no longer get the shots.

Long-term use of Depo-Provera may lead to loss of bone mineral density, which makes osteoporosis more likely. This risk is greater if you've taken the shot for longer than 2 years, especially if osteoporosis runs in your family, you drink a lot, you smoke, or you have other risk factors for the condition.

  • Irregular menstrual periods, or no periods at all
  • Headaches
  • Nervousness
  • Depression
  • Dizziness
  • Acne
  • Changes in appetite
  • Weight gain
  • Unwanted facial and body hair
  • Hair loss
  • Loss of bone mineral density

From: Birth Control Shot (Depo-Provera) WebMD Medical Reference

SOURCES:

FamilyDoctor.org: "Depo-Provera: An Injectable Contraceptive."

MedlinePlus: "Medroxyprogesterone Injection."

Sexuality Information and Education Council of the United States: "Talk About Sex."

Reviewed by Traci C. Johnson on August 5, 2019

SOURCES:

FamilyDoctor.org: "Depo-Provera: An Injectable Contraceptive."

MedlinePlus: "Medroxyprogesterone Injection."

Sexuality Information and Education Council of the United States: "Talk About Sex."

Reviewed by Traci C. Johnson on August 5, 2019

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Can I get pregnant after I stop using Depo-Provera?

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

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