CHRYSIN: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Chrysin belongs to a class of chemicals called flavonoids. It occurs naturally in various plants and substances, such as the passionflower, silver linden, and some geranium species; and in honey and bee propolis (glue).

People use chrysin for bodybuilding and for conditions such as anxiety, inflammation, gout, erectile dysfunction (ED), and many others, but there is no good scientific evidence to support these uses.

How does it work ?

Athletes are interested in chrysin for bodybuilding because laboratory research suggested that chrysin might increase the male hormone called testosterone and improve bodybuilding results. But research in humans hasn't found any effect on testosterone levels. The amount of chrysin that is absorbed from the intestine may be very small, which would make treatment effects unlikely.

Uses & Effectiveness ?

We currently have no information for CHRYSIN overview.

Side Effects

When taken by mouth: There isn't enough reliable information to know if chrysin is safe or what the possible side effects might be.

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if chrysin is safe or what the possible side effects might be.

Pregnancy and breast-feeding: There isn't enough reliable information to know if chrysin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Bleeding disorder: Chrysin might increase bleeding. There is some concern that it might increase the risk of bruising and bleeding in people with bleeding disorders.

Surgery: Chrysin might slow blood clotting. There is concern that it might increase the risk of extra bleeding during and after surgery. Stop taking chrysin at least 2 weeks before a scheduled surgery.

Interactions ?

Moderate Interaction

Be cautious with this combination

Medications for estrogen sensitive cancers (Aromatase inhibitors) interacts with CHRYSIN
Some types of cancer are affected by hormones in the body. Estrogen-sensitive cancers are cancers that are affected by estrogen levels in the body. Medications for estrogen sensitive cancers help decrease estrogen in the body. Chrysin might also decrease estrogen in the body. Taking chrysin along with medications for estrogen-sensitive cancers might decrease estrogen in the body too much.

Some medications for estrogen-sensitive cancers include aminoglutethimide (Cytadren), anastrozole (Arimidex), exemestane (Aromasin), letrozole (Femara), and others.
Birth control pills (Contraceptive drugs) interacts with CHRYSIN
Some birth control pills contain estrogen. Chrysin might decrease the effects of estrogen in the body. Taking chrysin along with birth control pills might decrease the effectiveness of birth control pills. If you take birth control pills along with chrysin, use an additional form of birth control such as a condom.

Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.
Estrogens interacts with CHRYSIN
Chrysin seems to decrease the effects of estrogen in the body. Taking chrysin along with estrogen pills might decrease the effectiveness of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with CHRYSIN
Using chrysin with medications that slow clotting might increase the risk of bleeding.

Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole (Persantine), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Diclofenac (Voltaren, others) interacts with CHRYSIN
The body breaks down diclofenac to get rid of it. Chrysin might decrease how quickly the body breaks down diclofenac. Taking chrysin along with diclofenac might increase the effects and side effects of diclofenac.
Mephenytoin (Mesantoin) interacts with CHRYSIN
The body breaks down mephenytoin to get rid of it. Chrysin might decrease how quickly the body breaks down mephenytoin. Taking chrysin along with mephenytoin might increase the effects and side effects of mephenytoin.

Minor Interaction

Be watchful with this combination

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with CHRYSIN
Some medications are changed and broken down by the liver. Chrysin might decrease how quickly the liver breaks down some medications. Taking chrysin along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking chrysin, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.
Medications changed by the liver (Glucuronidated drugs) interacts with CHRYSIN
The body breaks down some medications to get rid of them. The liver helps break down these medications. Chrysin might increase how quickly some medications are changed by the liver. This could decrease how well some of these medications work.

Some of these medications changed by the liver include acetaminophen, atorvastatin (Lipitor), diazepam (Valium), digoxin, entacapone (Comtan), estrogen, irinotecan (Camptosar), lamotrigine (Lamictal), lorazepam (Ativan), lovastatin (Mevacor), meprobamate, morphine, oxazepam (Serax), and others.
Testosterone interacts with CHRYSIN
The body breaks down testosterone to get rid of it. Chrysin might decrease how quickly the body breaks down testosterone. Taking chrysin along with testosterone might increase the effects and side effects of testosterone.

Dosing

The appropriate dose of chrysin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for chrysin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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CHRYSIN - Uses, Side Effects, and More

Overview

How does it work ?

Uses & Effectiveness ?

Side Effects

Special Precautions and Warnings

Interactions ?

Moderate Interaction

Medications for estrogen sensitive cancers (Aromatase inhibitors) interacts with CHRYSIN

Birth control pills (Contraceptive drugs) interacts with CHRYSIN

Estrogens interacts with CHRYSIN

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with CHRYSIN

Diclofenac (Voltaren, others) interacts with CHRYSIN

Mephenytoin (Mesantoin) interacts with CHRYSIN

Minor Interaction

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with CHRYSIN

Medications changed by the liver (Glucuronidated drugs) interacts with CHRYSIN

Testosterone interacts with CHRYSIN

Dosing

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