Akschota, Arbre au Sommeil, California Walnut, Coque de Noix, Feuille de Noyer Commun, Fructus Cortex, Gland Divin, Gland de Jupiter, He Tao, He Tao Shu Zhi, Hu Tao Ren, Juglans, Juglandis, Juglandis Folium, Juglans regia, Nogal, Nogal Inglés, Noix Anglaise, Noix de Grenoble, Noix Italienne, Noix Perse, Noyer Anglais, Noyer Commun, Noyer de Grenoble, Noyer Royal, Persian Walnut, Walnussblätter, Walnussfrüchtschalen, Walnut, Walnut Fruit, Walnut Hull, Walnut Leaf.


Overview Information

English walnut is a tree. The fruit (nut) is a popular food. The nut, the shell of the nut (hull), and the leaf are used to make medicine.

The nut is used as a part of the diet to lower cholesterol in people with high cholesterol. The nut, shell, and leaf are used for many other conditions, including diabetes, stomach problems, and skin conditions. But there is no good scientific research to support the use of English walnut for any of these other condiitons.

In foods, English walnut is commonly eaten as a snack, in baking, and in salads.

How does it work?

The nut of the English walnut contains chemicals called fatty acids, which might be useful as part of a cholesterol-lowering diet. It also contains chemicals that can expand blood vessels, possibly improving circulation and the way the heart works. Some of these chemicals might also help with swelling, pain, and cancer.


Uses & Effectiveness?

Possibly Effective for

  • High cholesterol. Eating walnuts as part of a low-fat diet seems to lower cholesterol. Total cholesterol and "bad cholesterol" (LDL) are decreased when walnuts are eaten instead of fatty foods and account for up to 20% of the calories in the diet. Substituting walnuts for other dietary fats also seems to improve the ratio between "good cholesterol" (HDL cholesterol) and total cholesterol in people with type 2 diabetes.

Insufficient Evidence for

More evidence is needed to rate the effectiveness of English walnut for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: The fruit (nut), shell, and leaf of English walnut are LIKELY SAFE for most people when eaten in usual food amounts. There isn't enough reliable information to know if the fruit or shell are safe in the larger amounts used as medicine. The leaf extract is POSSIBLY SAFE when taken at doses up to 200 mg daily for up to 3 months. The leaf extract can cause diarrhea. English walnut bark is POSSIBLY UNSAFE. Taking the bark daily might increase the risk for tongue or lip cancer.

When applied to the skin: English walnut bark is POSSIBLY UNSAFE. It contains a chemical called juglone that can irritate the skin.

Special Precautions & Warnings:

Pregnancy and breast-feeding: The fruit (nut), leaf, and shell of English walnut are LIKELY SAFE in food amounts. But there isn't enough information to know if these parts are safe in the larger amounts used as medicine. Stay on the safe side and stick to food amounts. English walnut bark is POSSIBLY UNSAFE. Don't take English walnut bark by mouth or apply it to the skin if you are pregnant or breastfeeding.



We currently have no information for ENGLISH WALNUT Interactions.



The following doses have been studied in scientific research:


  • For high cholesterol: 8-11 English walnut nuts or 30-56 grams (about 1/4 to 1/2 cup) have been substituted for fats in the diet.

View References


  • Anderson KJ, Teuber SS, Gobeille A, et al. Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation. J Nutr 2001;131:2837-42. View abstract.
  • Asero R. Detection and clinical characterization of patients with oral allergy syndrome caused by stable allergens in Rosaceae and nuts. Ann Allergy Asthma Immunol 1999;83:377-83. View abstract.
  • Bonamonte D, Foti C, Angelini G. Hyperpigmentation and contact dermatitis due to Juglans regia. Contact Dermatitis 2001;44:101-2. View abstract.
  • Chisholm A, Mann J, Skeaff M, et al. A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur J Clin Nutr 1998;52:12-6. View abstract.
  • Davis PA, Vasu VT, Gohil K, et al. A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth along with plasma insulin-like growth factor 1 in the transgenic adenocarcinoma of the mouse prostate model. Br J Nutr. 2012;108(10):1764-72. View abstract.
  • Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • FDA. Qualified Health Claims: Letter of Enforcement Discretion - Walnuts and Coronary Heart Disease (Docket No 02P-0292). March 2004. Available at: https://wayback.archive-it.org/7993/20171114183649/https:/www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm072910.htm. Accessed on March 9, 2020.
  • Feldman EB. The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J Nutr 2002;132:1062S-101S. View abstract.
  • Hosseini S, Jamshidi L, Mehrzadi S, et al. Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: a randomized double-blind, placebo-controlled clinical trial. J Ethnopharmacol. 2014;152(3):451-6. View abstract.
  • Hosseinzadeh H, Zarei H, Taghiabadi E. Antinociceptive, anti-inflammatory and acute toxicity effects of juglans regia L. leaves in mice. Iran Red Crescent Med J. 2011;13(1):27-33. View abstract.
  • Hu FB, Stampfer MJ. Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence. Curr Atheroscler Rep 1999;1:204-9. View abstract.
  • Inbaraj JJ, Chignell CF. Cytotoxic action of juglone and plumbagin: a mechanistic study using HaCaT keratinocytes. Chem Res Toxicol 2004;17:55-62. View abstract.
  • Perusquia M, Mendoza S, Bye R, et al. Vasoactive effects of aqueous extracts from five Mexican medicinal plants on isolated rat aorta. J Ethnopharmacol 1995;46:63-9. View abstract.
  • Rabiei K, Ebrahimzadeh MA, Saeedi M, et al. Effects of a hydroalcoholic extract of Juglans regia (walnut) leaves on blood glucose and major cardiovascular risk factors in type 2 diabetic patients: a double-blind, placebo-controlled clinical trial. BMC Complement Altern Med. 2018;18(1):206. View abstract.
  • Robbins WA, Xun L, FitzGerald LZ, et al. Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial. Biol Reprod. 2012;87(4):101. View abstract.
  • Ros E, Nunez I, Perez-Heras A, et al. A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. Circulation 2004;109:1609-14. View abstract.
  • Sabate J, Fraser GE, Burke K, et al. Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med 1993;328:603-7. View abstract.
  • Tapsell LC, Gillen LJ, Patch CS, et al. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care 2004;27:2777-83. View abstract.
  • Zambon D, Sabate J, Munoz S, et al. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann Intern Med 2000;132:538-46. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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