Oleic acid is most commonly used for preventing heart disease and reducing cholesterol. It is also used for preventing cancer and other conditions, but there is no good scientific evidence to support these other uses.
Don't confuse oleic acid with diets and oils containing oleic acid, such as the Mediterranean diet, olive oil, and canola oil or sunflower oil made to have higher levels of oleic acid. See separate listings for these topics.
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
- Heart disease. Using cooking oils that provide about 20 grams (1.5 tablespoons) of oleic acid in place of dietary fats with higher amounts of saturated fat might reduce the risk of heart disease. But research is limited.
- High cholesterol. Using cooking oils rich in oleic acid might help lower cholesterol. These oils include olive oil, some sunflower oils, and canola oil.
Insufficient Evidence for
- Bladder cancer. People with higher blood levels of oleic acid seem to have a lower risk of bladder cancer. But the amount of oleic acid in the blood can be affected by more than just intake from foods. So, it's still unclear if increasing intake of oleic acid from food reduces bladder cancer risk. It's also unknown if oleic acid supplements can help prevent bladder cancer.
- Breast cancer. Eating more foods that contain oleic acid doesn't seem to prevent breast cancer. It's unknown if oleic acid supplements can help prevent bladder cancer.
- Diabetes. Following a low-fat diet that includes food with oleic acid doesn't seem to lower cholesterol in people with diabetes.
- Diarrhea. Taking oleic acid might reduce the number of bowel movements in some people with diarrhea. But more research is needed.
- High blood pressure. Eating oil high in oleic acid might not help to lower high blood pressure. But more research is needed.
- Obesity. Some early research shows that using cooking oil containing oleic acid reduces fat around the abdomen by a small amount in people who are obese. It also seems to help to lower cholesterol in some people who are obese and at risk for heart disease. But using similar cooking oils without oleic acid also seem to have benefit. So, it's unclear if the oleic acid causes these improvements.
- Pancreatic cancer. People who get more oleic acid from their diet may have a lower risk of pancreatic cancer. But not all research agrees.
- Poor nutrient absorption that occurs when part of the small intestine is missing or removed (short bowel syndrome). Early research shows that taking oleic acid doesn't reduce diarrhea or help with nutrient absorption in people with short bowel syndrome.
- Stroke. People with higher blood levels of oleic acid seem to have a lower risk of stroke. But the amount of oleic acid in the blood can be affected by more than just intake from foods. So, it's still unclear if increasing intake of oleic acid from food reduces stroke risk. It's also unknown if oleic acid supplements can help prevent bladder cancer.
- A type of inflammatory bowel disease (ulcerative colitis). People who get more oleic acid from their diet might have a lower risk of ulcerative colitis. But not all research agrees.
- Rapid gastric emptying (dumping syndrome).
- Build up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD).
Special Precautions and Warnings
We currently have no information for OLEIC ACID overview.
- For heart disease: Using cooking oils that provide 20 grams (1.5 tablespoons) of oleic acid per day in place of other saturated fats and oils has been used.
- For high cholesterol: Cooking oils that contain high amounts of oleic acid in place of other saturated fats and oils has been used.
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Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiovascular disease risk in the canola oil multicenter randomized controlled trial. Am J Clin Nutr. 2014 Jul;100(1):88-97. View abstract.
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Tsuchiya A, Nagaya H, Kanno T, Nishizaki T. Oleic acid stimulates glucose uptake into adipocytes by enhancing insulin receptor signaling. J Pharmacol Sci. 2014;126(4):337-43. View abstract.
Voon PT, Ng TK, Lee VK, Nesaretnam K. Diets high in palmitic acid (16:0), lauric and myristic acids (12:0 + 14:0), or oleic acid (18:1) do not alter postprandial or fasting plasma homocysteine and inflammatory markers in healthy Malaysian adults. Am J Clin Nutr 2011;94:1451-7. View abstract.