People use lysine for cold sores (herpes labialis). They also use it for athletic performance, diabetes, and many other uses, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
- Cold sores (herpes labialis). Research suggests that lysine reduces the chance of getting cold sores when taken by mouth and also when applied as a cream to the skin. Applying a specific product containing lysine, zinc oxide, and 14 other ingredients (Super Lysine Plus +) seems to help cure cold sores faster. But not all research agrees.
Insufficient Evidence for
- Canker sores. Early research shows that taking 500 mg of lysine daily prevents canker sores and 4000 mg daily decreases how long canker sores are present.
- Diabetes. Some research shows that taking lysine twice daily can decrease blood sugar levels in people with diabetes. But not all research agrees.
- High levels of fats called triglycerides in the blood (hypertriglyceridemia). Early research suggests that taking lysine daily for 12 weeks, with or without vitamin B6, does not affect body weight, triglyceride levels, or blood sugar levels in men with high triglycerides. Taking lysine might actually reduce high-density lipoprotein (HDL or "good") cholesterol levels.
- Muscle strength. Early research suggests that consuming 80 mg/kg of lysine in the diet daily for 8 weeks improves forearm strength in young men.
- Bed sores (pressure ulcers). Research suggests that applying a cream containing lysine reduces bed sores in hospitalized adults. The cream seems to be most helpful in patients with more severe bed sores.
- Schizophrenia. Taking lysine by mouth seems to improve schizophrenia symptoms in some people taking prescription drugs. Research suggests that taking lysine three times daily for 8 weeks improves symptoms by about 34% in people who are not fully responding to the drug risperidone.
- Stress. Early research suggests that eating wheat that contains added lysine reduces stress in women and anxiety in men.
- Improving athletic performance.
- Other conditions.
Special Precautions and Warnings
Intolerance to lysinuric protein: Lysine supplementation might cause diarrhea and stomachcramps in children who are intolerant to lysinuric protein.
Calcium supplements interacts with LYSINE
Lysine can increase how much calcium the body absorbs. Taking calcium along with lysine can increase the amount of calcium in the body. Avoid taking large amounts of calcium and lysine at the same time.
Be cautious with this combination
- For cold sores (herpes labialis): 1000 mg of lysine taken daily in up to two divided doses for up to 12 months, or 1000 mg taken three times daily for 6 months has been used. For preventing cold sores from recurring, 500-1248 mg taken daily or 1000 mg taken three times daily has been used.
- For cold sores (herpes labialis): A specific combination of lysine plus zinc oxide and 14 other ingredients (Super Lysine Plus +) applied every 2 hours for 11 days has been used.
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