AUTUMN CROCUS
Colchicum, Colchicum autumnale, Colchicum speciosum, Colchicum vernum, Colchique, Colchique d'Automne, Cólquico, Crocus, Dame Sans Chemise, Fall Crocus, Faux-Safran, Gowri Gedde, Meadow Saffran, Meadow Saffron, Mysteria, Naked Ladies, Naked Lady, Safran Bâtard, Safran des Prés, Son-Before-The-Father, Tue-Chien, Tue-Loup, Upstart, Vellorita, Wild Saffron, Wonder Bulb.
Uses & Effectiveness
Insufficient Evidence for
- An inherited fever disorder (familial Mediterranean fever).
- Gout.
- Rheumatoid Arthritis (RA).
- Other conditions.
Side Effects & Safety
When taken by mouth: Autumn crocus is UNSAFE. It is poisonous, and can cause burning of the mouth and throat, vomiting, diarrhea, liver and kidney problems, blood disorders, nerve problems, shock, organ failure, and death. There have been reports of poisoning when autumn crocus was mistaken for onions, wild garlic, or wild leeks and eaten.If you have gout or familial Mediterranean fever, it is much safer to use colchicine prescribed by your healthcare provider. Prescription colchicine contains a set amount of medicine. The amount of colchicine in autumn crocus can vary from plant to plant.
Special Precautions & Warnings:
Pregnancy and breast-feeding: It's UNSAFE for anyone to use autumn crocus, but pregnant women have extra reasons to avoid use. Autumn crocus might cause birth defects.Interactions
Moderate Interaction
Be cautious with this combination
-
Colchicine interacts with AUTUMN CROCUS
Autumn crocus contains colchicine. Taking autumn crocus along with colchicine might increase the effects and side effects of colchicine.
Dosing
The appropriate dose of autumn crocus depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for autumn crocus. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
REFERENCES:
- Brvar, M., Kozelj, G., Mozina, M., and Bunc, M. Acute poisoning with autumn crocus (Colchicum autumnale L.). Wien.Klin Wochenschr. 3-31-2004;116(5-6):205-208. View abstract.
- Boisramé-Helms J, Rahmani H, Stiel L, Tournoud C, Sauder P. Extracorporeal life support in the treatment of colchicine poisoning. Clin Toxicol (Phila) 2015;53(8):827-9. View abstract.
- Brncic N, Viskovic I, Peric R, et al. Accidental plant poisoning with Colchicum autumnale: report of two cases. Croat Med J 2001;42(6):673-5. View abstract.
- Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
- Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, et al. [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. Schweiz Med Wochenschr 1996;126:1085-98. View abstract.
- Kritikos A, Spertini O. Reversible granulocyte abnormalities after accidental ingestion of Colchicum autumnale. Blood 2017;130(1):95. doi: 10.1182/blood-2017-02-766410. View abstract.
- Nagesh KR, Menezes RG, Rastogi P, et al. Suicidal plant poisoning with Colchicum autumnale. J Forensic Leg Med 2011;18(6):285-7. doi: 10.1016/j.jflm.2011.04.008. View abstract.
- Sundov Z, Nincevic Z, Definis-Gojanovic M, et al. Fatal colchicine poisoning by accidental ingestion of meadow saffron-case report. Forensic Sci Int 2005;149(2-3):253-6. View abstract.
- Wollersen H, Erdmann F, Risse M, Dettmeyer R. Accidental fatal ingestion of colchicine-containing leaves - toxicological and histological findings. Leg Med (Tokyo) 2009;11 Suppl 1:S498-9. doi: 10.1016/j.legalmed.2009.01.080. View abstract.
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