American Liverleaf, Anemone acutiloba, Anémone à Lobes Aigus, Anemone americana, Anemone hepatica, Anémone d'Amérique, Anémone Hépatique, Bryopsidée, Hepatica nobilis var. acuta, Hepatica nobilis var. obtusa, Hepática, Hepatici Noblis Herba, Hépatique d'Amérique, Hépatique à Lobes Aigus, Herb Trinity, Kidney Wort, Leberbluemchenkraut, Liverleaf, Liverweed, Liverwort-Leaf, Round-Leaved Hepatica, Round-Lobe Hepatica, Sharp-Lobe Hepatica, Trefoil.


Overview Information

Liverwort is a plant. People make medicine out of the fresh or dried parts that grow above the ground.

Despite serious safety concerns, liverwort is used for treating gallstones, liver conditions, stomach and digestive disorders, hemorrhoids, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work?

There isn't enough reliable information to know how liverwort works or what effect it has on the body.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of liverwort for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Fresh liverwort is LIKELY UNSAFE. It can cause side effects such as diarrhea, stomach irritation, and kidney and urinary tract irritation. There isn't enough reliable information to know if dried liverwort is safe or what the side effects might be.

When applied to the skin: Fresh liverwort is LIKELY UNSAFE. It can cause irritation, itching, and pus-filled blisters. There isn't enough reliable information to know if dried liverwort is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: It is LIKELY UNSAFE to take fresh liverwort by mouth or apply it to the skin. It's especially important to avoid using fresh liverwort if you are pregnant or breast-feeding. There isn't enough reliable information to know if dried liverwort is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.



We currently have no information for LIVERWORT Interactions.



The appropriate dose of liverwort depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for liverwort. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Storrs, F. J., Mitchell, J. C., and Rasmussen, J. E. Contact hypersensitivity to liverwort and the compositae family of plants. Cutis 1976;18(5):681-686. View abstract.
  • Tamehiro, N., Sato, Y., Suzuki, T., Hashimoto, T., Asakawa, Y., Yokoyama, S., Kawanishi, T., Ohno, Y., Inoue, K., Nagao, T., and Nishimaki-Mogami, T. Riccardin C: a natural product that functions as a liver X receptor (LXR)alpha agonist and an LXRbeta antagonist. FEBS Lett 10-10-2005;579(24):5299-5304. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.