Bedana, Cognassier, Coing, Coudonnier, Cydonia oblongata, Cydonia vulgaris, Marmelo, Membrillo, Pommier de Cydon, Pyrus cydonia, Quitte, Quittenbaum.


Overview Information

Quince is a small tree bearing a yellow fruit. The seed, fruit, and leaves are used as medicine.

Quince fruit syrup is sometimes used for persistent heartburn in children. Quince is also used for morning sickness, hay fever, stomach ulcers, and many other conditions, but there is no good scientific evidence to support these uses.

In foods, quince fruit is used to make jam, jelly, marmalade, and pudding. It is also used to make juice and wine.

How does it work?

Some chemicals in quince might reduce how the immune system responds to substances that cause allergic reactions.


Uses & Effectiveness?

Possibly Effective for

  • Persistent heartburn. Taking quince fruit syrup twice daily seems to reduce symptoms of persistent heartburn in children and teens by a small amount.

Insufficient Evidence for

More evidence is needed to rate the effectiveness of quince for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: There isn't enough reliable information to know if quince fruit is safe for medicinal use. The seeds contain cyanide, which suggests that quince seeds might not be safe.

When applied to the skin: There isn't enough reliable information to know if quince is safe or what the side effects might be.

Special Precautions & Warnings:

Children: Quince fruit syrup is POSSIBLY SAFE when taken by mouth for up to 4 weeks in children ages 7 months and older. There were no reported side effects.

Pregnancy and breast-feeding: There isn't enough reliable information to know if quince is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.



Major Interaction

Do not take this combination

  • Medications taken by mouth (Oral drugs) interacts with QUINCE

    Quince contains a type of soft fiber called mucilage. Mucilage can decrease how much medicine the body absorbs. Taking quince at the same time you take medications by mouth can decrease the effectiveness of your medication. To prevent this interaction take quince at least one hour after medications you take by mouth.



The following doses have been studied in scientific research:



  • For persistent heartburn: 0.25-0.3 mL/kg of quince fruit syrup has been used twice daily for 4 weeks in children 7 months and older.

View References


  • Baars EW, Savelkoul HF. Citrus/Cydonia comp. can restore the immunological balance in seasonal allergic rhinitis-related immunological parameters in vitro. Mediators Inflamm. 2008;2008:496467. View abstract.
  • Costa RM, Magalhães AS, Pereira JA, et al. Evaluation of free radical-scavenging and antihemolytic activities of quince (Cydonia oblonga) leaf: a comparative study with green tea (Camellia sinensis). Food Chem Toxicol. 2009;47(4):860-5. View abstract.
  • Essafi-Benkhadir K, Refai A, Riahi I, Fattouch S, Karoui H, Essafi M. Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-?B, p38MAPK and Akt inhibition. Biochem Biophys Res Commun. 2012;418(1):180-5. View abstract.
  • Gründemann C, Papagiannopoulos M, Lamy E, Mersch-Sundermann V, Huber R. Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. Phytomedicine. 2011;18(8-9):760-8. View abstract.
  • Hoffmann A, Klein SD, Gründemann C, Garcia-Käufer M, Wolf U, Huber R. Efficacy of a nasal spray from Citrus limon and Cydonia oblonga for the treatment of hay fever symptoms-A randomized, placebo controlled cross-over study. Phytother Res. 2016;30(9):1481-6. View abstract.
  • Huber R, Stintzing FC, Briemle D, Beckmann C, Meyer U, Gründemann C. In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits. Planta Med. 2012;78(4):334-40. View abstract.
  • Jafari-Dehkordi E, Hashem-Dabaghian F, Aliasl F, et al. Comparison of quince with vitamin B6 for treatment of nausea and vomiting in pregnancy: a randomised clinical trial. J Obstet Gynaecol. 2017;37(8):1048-1052. View abstract.
  • Kawahara T, Tsutsui K, Nakanishi E, Inoue T, Hamauzu Y. Effect of the topical application of an ethanol extract of quince seeds on the development of atopic dermatitis-like symptoms in NC/Nga mice. BMC Complement Altern Med. 2017;17(1):80. View abstract.
  • Naeimi M, Kianifar H, Memariani Z, et al. Comparison of the efficacy of ranitidine and quince syrup on gastroesophageal reflux disease in children. Complement Ther Med 2019;45:215-21. View abstract.
  • Pacifico S, Gallicchio M, Fiorentino A, Fischer A, Meyer U, Stintzing FC. Antioxidant properties and cytotoxic effects on human cancer cell lines of aqueous fermented and lipophilic quince (Cydonia oblonga Mill.) preparations. Food Chem Toxicol. 2012;50(11):4130-5. View abstract.
  • Shinomiya F, Hamauzu Y, Kawahara T. Anti-allergic effect of a hot-water extract of quince (Cydonia oblonga). Biosci Biotechnol Biochem. 2009;73(8):1773-8. View abstract.
  • Zohalinezhad ME, Imanieh MH, Samani SM, et al. Effects of Quince syrup on clinical symptoms of children with symptomatic gastroesophageal reflux disease: A double-blind randomized controlled clinical trial. Complement Ther Clin Pract. 2015;21(4):268-76. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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