Ballico, Cernilton, Cernitin, Extrait de Pollen d'Ivraie, Extrait de Pollen de Plante Herbacée, Flower Pollen Extract, Graminex, Grass Pollen, Grass Pollen Extract, Ivraie, Pollen d'Ivraie, Pollen de Plante Herbacée, Pollen Extract, Raygrás, Ray-Grass, Rye, Rye Grass Pollen, Rye Grass Pollen Extract, Rye Pollen Extract, Rye-Grass Pollen, Rye-Grass Pollen Extract, Secale cereale.


Overview Information

Rye grass is a plant. Pollen from rye grass is used to make medicine. A product made from rye grass pollen extract (Cernilton) is a registered pharmaceutical product in Western Europe, Japan, Korea, and Argentina.

Rye grass pollen extract is commonly used by mouth for prostate conditions such as benign prostatic hyperplasia (BPH), prostate pain, and ongoing swelling of the prostate.

How does it work?

Chemicals found in rye grass pollen decrease swelling (inflammation) by interfering with certain chemicals. These chemicals might also slow down the growth of prostate cancer cells. Rye grass fiber might promote the growth and activity of healthy bacteria in the gut. This helps to promote regularity.


Uses & Effectiveness?

Possibly Effective for

  • Symptoms of an enlarged prostate (benign prostatic hyperplasia, BPH). Taking rye grass pollen extract (Cernilton) seems to improve symptoms of an enlarged prostate, but research is mixed about whether or not it actually affects the size of the prostate. It is not known if rye grass pollen extract works as well as prescription drugs such as finasteride (Proscar) or alpha-blockers. However, rye grass pollen does seem to work about as well as Pygeum and Paraprost, a Japanese prostate remedy containing L-glutamic acid, L-alanine, and aminoacetic acid.
  • Shrinking an enlarged prostate, prostate swelling, and pain. Taking rye grass pollen extract (Cernilton) seems to reduce prostate pain caused by an enlarged prostate or prostate swelling. However, it might not reduce all symptoms associated with an enlarged prostate, such as the amount of urine produced or issues having sex. People with fewer symptoms usually see more improvement using rye grass pollen extract.

Insufficient Evidence for

  • Constipation. Eating bread containing rye grass as the fiber source seems to improve stool softness along with ease and frequency of bowel movements in people with constipation.
  • Other conditions.
More evidence is needed to rate the effectiveness of rye grass for these uses.

Side Effects

Side Effects & Safety

Rye grass and rye grass pollen extract are LIKELY SAFE for most people. Rye grass pollen extract can cause side effects such as stomach swelling (distention), heartburn, and nausea.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of rye grass pollen extract during pregnancy and breast-feeding. Stay on the safe side and avoid use.



We currently have no information for RYE GRASS Interactions.



The following doses have been studied in scientific research:


  • For symptoms of an enlarged prostate (benign prostatic hyperplasia, BPH): Up to 2 tablets of rye grass pollen extract (Cernilton) 3 times per day.
  • For shrinking an enlarged prostate, prostate swelling, and pain: Up to 2 tablets of rye grass pollen extract (Cernilton) 3 times per day.

View References


  • Buck AC, Cox R, Rees RW, et al. Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study. Br J Urol 1990;66:398-404. View abstract.
  • Buck AC, Rees RW, Ebeling L. Treatment of chronic prostatitis and prostatodynia with pollen extract. Br J Urol 1989;64:496-9. View abstract.
  • Dutkiewicz S. Usefulness of Cernilton in the treatment of benign prostatic hyperplasia. Int Urol Nephrol 1996;28:49-53.. View abstract.
  • Habib FK, Ross M, Lewenstein A, et al. Identification of a prostate inhibitory substance in a pollen extract. Prostate 1995;26:133-9. View abstract.
  • Holma R, Hongisto SM, Saxelin M, Korpela R. Constipation is relieved more by rye bread than wheat bread or laxatives without increased adverse gastrointestinal effects. J Nutr 2010;140(3):534-41. View abstract.
  • Loschen G, Ebeling L. [Inhibition of arachidonic acid cascade by extract of rye pollen]. Arzneimittelforschung 1991;41:162-7. View abstract.
  • Lowe FC, Dreikorn K, Borkowski A, et al. Review of recent placebo-controlled trials utilizing phytotherapeutic agents for treatment of BPH. Prostate 1998;37:187-93. View abstract.
  • Lowe FC, Ku JC. Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urol 1996;48:12-20. View abstract.
  • MacDonald R, Ishani A, Rutks I, Wilt TJ. A systematic review of Cernilton for the treatment of benign prostatic hyperplasia. BJU Int 2000;85:836-41. View abstract.
  • Maekawa M, Kishimoto T, Yasumoto R, et al. [Clinical evaluation of Cernilton on benign prostatic hypertrophy--a multiple center double-blind study with Paraprost]. Hinyokika Kiyo 1990;36:495-516. View abstract.
  • Preuss H, Debasis B, Walter GC. A Critical review of Cernitin for symptomatic relief of lower urinary tract symptoms (LUTS) in men. Res Comm Pharm Toxicol 2003;8.
  • Rugendorff EW, Weidner W, Ebeling L, Buck AC. Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia. Br J Urol 1993;71:433-8. View abstract.
  • Wagenlehner FM, Schneider H, Ludwig M, et al. A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study. Eur Urol 2009;56(3):544-51. View abstract.
  • Yasumoto R, Kawanishi H, Tsujino T, et al. Clinical evaluation of long-term treatment using cernitin pollen extract in patients with benign prostatic hyperplasia. Clin Ther 1995;17:82-7. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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