Ananas de Sibérie, Argasse, Argousier, Argousier Faux-Nerprun, Bourdaine Marine, Buckthorn, Chharma, Dhar-Bu, Épine Luisante, Épine Marrante, Espino Armarillo, Espino Falso, Faux Nerprun, Finbar, Grisset, Hippophae rhamnoides, Meerdorn, Oblepikha, Olivier de Sibérie, Purging Thorn, Rokitnik, Sallow Thorn, Sanddorn, Saule Épineux, Sea Buckhorn, Sceitbezien, Sea-Buckthorn, Seedorn, Star-Bu, Tindved.<br/><br/>
Overview InformationSea buckthorn is a plant. The leaves, flowers, seeds, and fruits are used to make medicine.
Sea buckthorn leaves and flowers are used for treating arthritis, gastrointestinal ulcers, gout, and skin rashes caused by infectious diseases such as measles. A tea containing sea buckthorn leaves is used as a source of vitamins, antioxidants, protein building blocks (amino acids), fatty acids and minerals; for improving blood pressure and lowering cholesterol; preventing and controlling blood vessel diseases; and boosting immunity.
Sea buckthorn berries are used for preventing infections, improving sight, and slowing the aging process.
The seed or berry oil is used as an expectorant for loosening phlegm; for treating asthma, heart disorders including chest pain (angina) and high cholesterol; for preventing blood vessel disease; and as an antioxidant. Sea buckthorn oil is also used for slowing the decline of thinking skills with age; reducing illness due to cancer, as well as limiting the toxicity of chemical cancer treatment (chemotherapy); balancing the immune system; treating stomach and intestinal diseases including ulcers and reflux esophagitis (GERD); treating night blindness and dry eye; and as a supplemental source of vitamins C, A, and E, beta-carotene, minerals, amino acids, and fatty acids.
Some people apply sea buckthorn berries, berry concentrate, and berry or seed oil directly to the skin for preventing sunburn; for treating radiation damage from x-rays and sunburns; for healing wounds including bedsores, burns, and cuts; for acne, dermatitis, dry skin, eczema, skin ulcers, and skin color changes after giving birth; and for protecting mucus membranes.
In foods, sea buckthorn berries are used to make jellies, juices, purees, and sauces.
In manufacturing, sea buckthorn is used in cosmetics and anti-aging products.
How does it work?Sea buckthorn contains vitamins A, B1, B2, B6, C, and other active ingredients. It might have some activity against stomach and intestinal ulcers, and heartburn symptoms.
Uses & Effectiveness
Possibly Ineffective for
- A skin condition called atopic dermatitis (eczema). Early research shows that taking sea buckthorn pulp oil by mouth for 4 months improves atopic dermatitis. However, sea buckthorn seed oil taken by mouth does not have this effect. Also, applying cream containing 10% or 20% sea buckthorn on the skin for 4 weeks does not seem to improve symptoms of mild-to-moderate atopic dermatitis.
Insufficient Evidence for
- Aging skin. Early research shows that taking a specific combination supplement containing sea buckthorn berry oil and other ingredients by mouth might improve wrinkles and sun-damaged skin when used along with a skin cream containing 0.1% tazarotene.
- Heart disease. Developing research in China suggests that taking a particular sea buckthorn extract three times by mouth for 6 weeks lowers cholesterol, reduces chest pain, and improves heart function in people with heart disease.
- Common cold. Early research suggests that consuming sea buckthorn berries in a frozen puree for 90 days does not prevent the common cold or make symptoms go away faster.
- Digestive tract infection. Early research suggests that consuming sea buckthorn berries in frozen puree for 90 days does not prevent digestive tract infections.
- Dry eye. Some early research shows that taking a specific sea buckthorn product by mouth decreases feelings of eye redness and burning.
- A type of stomach illness (functional dyspepsia). Early research suggests that taking sea buckthorn may help regulate the appetite children with functional dyspepsia. But sea buckthorn doesn't appear to improve the rate at which food empties from the stomach into the intestines.
- Dialysis. Early research shows that taking sea buckthorn oil daily for 8 weeks does not help remove waste products from the blood or prevent dry mouth in people undergoing dialysis.
- High blood pressure. Early research suggests that taking sea buckthorn by mouth for up to 8 months might reduce high blood pressure similarly to certain blood pressure-lowering drugs.
- Liver disease (cirrhosis). There is some early evidence showing that taking sea buckthorn extract might reduce liver enzymes and other chemicals in the blood that indicate liver problems.
- A kidney disease called nephrotic syndrome. Early research shows that taking sea buckthorn by mouth in addition to standard care helps reduce swelling, improve appetite, and reduce the amount of protein in the urine in people with nephrotic syndrome. It's not clear if these improvements with sea buckthorn plus standard care are better than what would be achieved with standard care alone.Vaginal thinning. Early research suggests that taking sea buckthorn oil daily does not improve symptoms of vaginal thinning in postmenopausal women.
- Weight loss. Early evidence shows that taking sea buckthorn berries, berry oil, or extract by mouth does not reduce body weight in overweight or obese women.
- Chest pain (angina).
- Dry skin.
- High cholesterol.
- Pressure ulcers.
- Stomach ulcers.
- Vision disorders.
- Other conditions.
Side Effects & SafetySea buckthorn fruit is LIKELY SAFE when consumed as food. Sea buckthorn fruit is used in jams, pies, drinks, and other foods. Sea buckthorn fruit is POSSIBLY SAFE when taken by mouth or used on the skin as a medicine. It has been safely used in scientific studies lasting up to 90 days.
However, not enough is known about the safety of using sea buckthorn leaf or extracts.
Special Precautions & Warnings:Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking sea buckthorn if you are pregnant or breast-feeding. Stay on the safe side and avoid use.
Bleeding disorder: Sea buckthorn might slow blood clotting when taken as a medicine. There is some concern that it might increase the risk of bruising and bleeding in people with bleeding disorders.
Low blood pressure: Sea buckthorn might lower blood pressure when taken as a medicine. In theory, taking sea buckthorn might make blood pressure become too low in people with low blood pressure.
Surgery: Sea buckthorn might slow blood clotting when taken as a medicine. There is some concern that it might cause extra bleeding during and after surgery. Stop using sea buckthorn at least 2 weeks before a scheduled surgery.
Be cautious with this combination
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with SEA BUCKTHORN
Sea buckthorn might slow blood clotting. Taking sea buckthorn along with medications that also slow clotting might increase the chances of bruising and bleeding.<br /> Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
The appropriate dose of sea buckthorn depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for sea buckthorn. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
- Kallio H, Yang B, Peippo P. Effects of different origins and harvesting time on vitamin C, tocopherols, and tocotrienols in sea buckthorn (Hippophae rhamnoides) berries. J Agric Food Chem 2002;50:6136-42.. View abstract.
- Larmo P, Alin J, Salminen E, et al. Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. Eur J Clin Nutr 2008;62:1123-30. View abstract.
- Larmo PS, Jarvinen RL, Setala NL, et al. Oral sea buckthorn oil attenuates tear film osmolarity and symptoms in individuals with dry eye. J Nutr 2010;140:1462-8. View abstract.
- Larmo PS, Kangas AJ, Soininen P, et al. Effects of sea buckthorn and bilberry on serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized crossover trial. Am J Clin Nutr. 2013;98(4):941-51. View abstract.
- Larmo PS, Yang B, Hyssälä J, et al. Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study. Maturitas. 2014;79(3):316-21. View abstract.
- Lehtonen, H. M., Suomela, J. P., Tahvonen, R., Yang, B., Venojarvi, M., Viikari, J., and Kallio, H. Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women. Eur J Clin Nutr 2011;65(3):394-401. View abstract.
- Li Y, Liu H. Prevention of tumour production in rats fed aminopyrine plus nitrite by sea buckthorn juice. IARC Sci Publ 1991;105:568-70. View abstract.
- Li, Y., Xu, C., Zhang, Q., Liu, J. Y., and Tan, R. X. In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases. J Ethnopharmacol 4-26-2005;98(3):329-333. View abstract.
- Rodhe Y, Woodhill T, Thorman R, Möller L, Hylander B. The effect of sea buckthorn supplement on oral health, inflammation, and DNA damage in hemodialysis patients: a double-blinded, randomized crossover study. J Ren Nutr. 2013;23(3):172-9. View abstract.
- Singh RG, Singh P, Singh PK, et al. Immunomodulating and antiproteinuric effect of Hippophae rhamnoides (Badriphal) in idiopathic nephrotic syndrome. J Assoc Physicians India. 2013;61(6):397-9. View abstract.
- Suomela JP, Ahotupa M, Yang B, et al. Absorption of flavonols derived from sea buckthorn (Hippophaë rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. J Agric Food Chem 2006;54:7364-9. View abstract.
- Wang Y, Lu Y, Liu X, et al. [The protective effect of Hippophae rhamnoides L. on hyperlipidemic serum cultured smooth muscle cells in vitro]. Chung Kuo Chung Yao Tsa Chih 1992;17:601, 624-6. View abstract.
- Weiss RF. Herbal medicine. 5th ed. Beaconsfield, UK: Beaconsfield Publishers Ltd, 1998.
- Xiao M, Qiu X, Yue D, et al. Influence of hippophae rhamnoides on two appetite factors, gastric emptying and metabolic parameters, in children with functional dyspepsia. Hell J Nucl Med. 2013;16(1):38-43. View abstract.
- Xiao M, Yang Z, Jiu M, et al. [The antigastroulcerative activity of beta-sitosterol-beta-D-glucoside and its aglycone in rats]. Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992;23:98-101. View abstract.
- Zeb A. Chemical and nutritional constituents of sea buckthorn. Pakistan Journal of Nutrition 2004;3:99-106.
- Zhang Maoshun, et al. Treatment of ischemic heart diseases with flavonoids of Hippophae rhamnoides. Chinese Journal of Cardiology 1987;15:97-9.
- Zhongrui L, Shuzhen T. [Clinical observation on curative effect of oral seabuckthorn seed oil on cancers under chemotherapy]. Hippophae 1993;6:39-41.
- Bala M, Prasad J, Singh S, Tiwari S, and Sawhney RC. Whole-body radioprotective effects of SBL-1: a preparation from leaves of Hippophae rhamnoides. Journal of Herbs, Spices & Medicinal Plants 2009;15(2):203-15.
- Bao, M. and Lou, Y. Flavonoids from seabuckthorn protect endothelial cells (EA.hy926) from oxidized low-density lipoprotein induced injuries via regulation of LOX-1 and eNOS expression. J.Cardiovasc.Pharmacol. 2006;48(1):834-841. View abstract.
- Bath-Hextall, F. J., Jenkinson, C., Humphreys, R., and Williams, H. C. Dietary supplements for established atopic eczema. Cochrane.Database.Syst.Rev. 2012;2:CD005205. View abstract.
- Benherlal, P. S. and Arumughan, C. Studies on modulation of DNA integrity in Fenton's system by phytochemicals. Mutat.Res. 12-15-2008;648(1-2):1-8. View abstract.
- Boivin, D., Blanchette, M., Barrette, S., Moghrabi, A., and Beliveau, R. Inhibition of cancer cell proliferation and suppression of TNF-induced activation of NFkappaB by edible berry juice. Anticancer Res 2007;27(2):937-948. View abstract.
- Cao, Q., Qu, W., Deng, Y., Zhang, Z., Niu, W., and Pan, Y. [Effect of flavonoids from the seed and fruit residue of Hippophae rhamnoides L. on glycometabolism in mice]. Zhong.Yao Cai. 2003;26(10):735-737. View abstract.
- Chang BB, Wang F Xu TY Zhang QQ He J Zhang XJ Li J. Total flavones of Hippophae rhamnoides L. for essential hypertension: a systematic review of randomized controlled trials. Chinese Journal of Evidence-Based Medicine. 2009;9(11):1207-1213.
- Chauhan, A. S., Negi, P. S., and Ramteke, R. S. Antioxidant and antibacterial activities of aqueous extract of Seabuckthorn (Hippophae rhamnoides) seeds. Fitoterapia 2007;78(7-8):590-592. View abstract.
- Chawla, R., Arora, R., Singh, S., Sagar, R. K., Sharma, R. K., Kumar, R., Sharma, A., Gupta, M. L., Singh, S., Prasad, J., Khan, H. A., Swaroop, A., Sinha, A. K., Gupta, A. K., Tripathi, R. P., and Ahuja, P. S. Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides. J.Med.Food 2007;10(1):101-109. View abstract.
- Chen, L., He, T., Han, Y., Sheng, J. Z., Jin, S., and Jin, M. W. Pentamethylquercetin improves adiponectin expression in differentiated 3T3-L1 cells via a mechanism that implicates PPARgamma together with TNF-alpha and IL-6. Molecules. 2011;16(7):5754-5768. View abstract.
- Cheng, J., Kondo, K., Suzuki, Y., Ikeda, Y., Meng, X., and Umemura, K. Inhibitory effects of total flavones of Hippophae Rhamnoides L on thrombosis in mouse femoral artery and in vitro platelet aggregation. Life Sci. 4-4-2003;72(20):2263-2271. View abstract.
- Degtiareva, I. I., Toteva, Ets, Litinskaia, E. V., Matvienko, A. V., Iurzhenko, N. N., Leonov, L. N., Khomenko, E. V., and Nevstruev, V. P. [Degree of lipid peroxidation and vitamin E level during the treatment of peptic ulcer]. Klin Med (Mosk) 1991;69(7):38-42. View abstract.
- Dorhoi, A., Dobrean, V., Zahan, M., and Virag, P. Modulatory effects of several herbal extracts on avian peripheral blood cell immune responses. Phytother.Res. 2006;20(5):352-358. View abstract.
- Dubey, G. P, Agrawal, Aruna, Gupta, B. S, and Udupa, K. N. Neurophysiological adaptation following cold stress under the influence of Badriphal (Hippophae rhamnoides L.). Pharmacopsychoecologia. 1990;3(2):59-63.
- Dubey, G. P., Agrawal, A., and Dixit, S. P. Role of Seabuckthorn (Hippophae rhamnoides) in the maintenance of cardiovascular homeostasis following cold stress. Journal of Natural Remedies 2003;3:36-40.
- Eccleston, C., Baoru, Y., Tahvonen, R., Kallio, H., Rimbach, G. H., and Minihane, A. M. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J Nutr.Biochem. 2002;13(6):346-354. View abstract.
- Geetha, S., Ram, M. S., Sharma, S. K., Ilavazhagan, G., Banerjee, P. K., and Sawhney, R. C. Cytoprotective and antioxidant activity of seabuckthorn (Hippophae rhamnoides L.) flavones against tert-butyl hydroperoxide-induced cytotoxicity in lymphocytes. J.Med.Food 2009;12(1):151-158. View abstract.
- Geetha, S., Sai, Ram M., Mongia, S. S., Singh, V., Ilavazhagan, G., and Sawhney, R. C. Evaluation of antioxidant activity of leaf extract of Seabuckthorn (Hippophae rhamnoides L.) on chromium(VI) induced oxidative stress in albino rats. J Ethnopharmacol. 2003;87(2-3):247-251. View abstract.
- Geetha, S., Sai, Ram M., Singh, V., Ilavazhagan, G., and Sawhney, R. C. Anti-oxidant and immunomodulatory properties of seabuckthorn (Hippophae rhamnoides)--an in vitro study. J Ethnopharmacol. 2002;79(3):373-378. View abstract.
- Gong M, Liao XY Zhang MS et al. Effects of total flavones of Hippopphae Rhamnoides L (TFH) on anti-hypertension and insulin sensitivity. Modern Chinese Medicine Magazine. 2000;9(14):1303.
- Grad, S. C., Muresan, I., and Dumitrascu, D. L. Generalized yellow skin caused by high intake of sea buckthorn. Forsch.Komplementmed. 2012;19(3):153-156. View abstract.
- Gupta, A., Upadhyay, N. K., Sawhney, R. C., and Kumar, R. A poly-herbal formulation accelerates normal and impaired diabetic wound healing. Wound.Repair Regen. 2008;16(6):784-790. View abstract.
- Gupta, R. and Flora, S. J. S. Protective effects of fruit extracts of Hippophae rhamnoides L. against arsenic toxicity in Swiss albino mice. Human & Experimental Toxicology 2006;25(6):285-295.
- Gupta, Vanita, Bala, Madhu, Prasad, Jagdish, Singh, Surinder, and Gupta, Manish. Leaves of Hippophae Rhamnoides Prevent Taste Aversion in Gamma-Irradiated Rats. (includes abstract). Journal of Dietary Supplements 2011;8(4):355-368.
- Han QH, Zhang GT Shang MS. How does the total flavones of Hippopphae Rhamnoides L (TFH) work in improving left ventricular posterior wall thickness in patients with hypertension. China Eastern and Western Medicine magazine. 2001;21(3):215.
- Jain, M., Ganju, L., Katiyal, A., Padwad, Y., Mishra, K. P., Chanda, S., Karan, D., Yogendra, K. M., and Sawhney, R. C. Effect of Hippophae rhamnoides leaf extract against Dengue virus infection in human blood-derived macrophages. Phytomedicine. 2008;15(10):793-799. View abstract.
- Jarvinen, R. L., Larmo, P. S., Setala, N. L., Yang, B., Engblom, J. R., Viitanen, M. H., and Kallio, H. P. Effects of oral sea buckthorn oil on tear film Fatty acids in individuals with dry eye. Cornea 2011;30(9):1013-1019. View abstract.
- Kasparaviciene, G., Briedis, V., and Ivanauskas, L. [Influence of sea buckthorn oil production technology on its antioxidant activity]. Medicina (Kaunas.) 2004;40(8):753-757. View abstract.
- Khamraev, A. K. and Kalmykova, A. S. [Effect of Hippophae rhamnoides oil on the lipid concentration of serum, T-, B- and O-lymphocytes in acute pneumonia in young children]. Pediatriia. 1986;(9):75. View abstract.
- Koyama, T., Taka, A., and Togashi, H. Effects of a herbal medicine, Hippophae rhamnoides, on cardiovascular functions and coronary microvessels in the spontaneously hypertensive stroke-prone rat. Clin.Hemorheol.Microcirc. 2009;41(1):17-26. View abstract.
- Kwon, D. J., Bae, Y. S., Ju, S. M., Goh, A. R., Choi, S. Y., and Park, J. Casuarinin suppresses TNF-alpha-induced ICAM-1 expression via blockade of NF-kappaB activation in HaCaT cells. Biochem.Biophys.Res.Commun. 6-17-2011;409(4):780-785. View abstract.
- Larmo, P. S., Yang, B., Hurme, S. A., Alin, J. A., Kallio, H. P., Salminen, E. K., and Tahvonen, R. L. Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. Eur.J.Nutr. 2009;48(5):277-282. View abstract.
- Lehtonen, H. M., Jarvinen, R., Linderborg, K., Viitanen, M., Venojarvi, M., Alanko, H., and Kallio, H. Postprandial hyperglycemia and insulin response are affected by sea buckthorn (Hippophae rhamnoides ssp. turkestanica) berry and its ethanol-soluble metabolites. Eur.J.Clin.Nutr. 2010;64(12):1465-1471. View abstract.
- Lehtonen, H. M., Lehtinen, O., Suomela, J. P., Viitanen, M., and Kallio, H. Flavonol glycosides of sea buckthorn (Hippophae rhamnoides ssp. sinensis) and lingonberry (Vaccinium vitis-idaea) are bioavailable in humans and monoglucuronidated for excretion. J.Agric.Food Chem. 1-13-2010;58(1):620-627. View abstract.
- Liao XY, Zhang MS Wang WW et al. Effects of total flavones of Hippopphae Rhamnoides L (TFH) on carbon monoxide production of atrial hypertensive patients. Western China Medicine. 2005;20(2):247-248.
- Linderborg, K. M., Lehtonen, H. M., Jarvinen, R., Viitanen, M., and Kallio, H. The fibres and polyphenols in sea buckthorn (Hippophae rhamnoides) extraction residues delay postprandial lipemia. Int.J.Food Sci.Nutr. 2012;63(4):483-490. View abstract.
- Manea, S., Mazilu, E., Ristea, C., Setnic, S., Popescu, M., and et al. Comparative determination of certain antioxidants in sea buckthorn (Hippophae rhamnoides) leaves, fruits, juice, oil and oil extraction residues. Farmacia (Romania) 2006;54:97-103.
- Mansurova, I. D., Linchevskaia, A. A., Molchagina, R. P., and Bobodzhanova, M. B. [Oleum hippophae, a stabilizer of biological membranes]. Farmakol Toksikol. 1978;41(1):105-109. View abstract.
- Mishra, K. P., Chanda, S., Karan, D., Ganju, L., and Sawhney, R. C. Effect of Seabuckthorn (Hippophae rhamnoides) flavone on immune system: an in-vitro approach. Phytother.Res. 2008;22(11):1490-1495. View abstract.
- Nemes-Nagy, E., Szocs-Molnar, T., Dunca, I., Balogh-Samarghitan, V., Hobai, S., Morar, R., Pusta, D. L., and Craciun, E. C. Effect of a dietary supplement containing blueberry and sea buckthorn concentrate on antioxidant capacity in type 1 diabetic children. Acta Physiol Hung. 2008;95(4):383-393. View abstract.
- Nikitin, V. A., Chistiakov, A. A., and Bugaeva, V. I. [Therapeutic endoscopy in combined therapy of gastroduodenal ulcers]. Khirurgiia (Mosk) 1989;(4):33-35. View abstract.
- Nikulin, A. A., Iavorskii, A. N., Petrov, V. K., Tishkin, V. S., and Rachkov, A. K. [Effect of sea buckthorn, dog rose and sperm oils, preparation "Spedian-2M" on several indices of carbohydrate metabolism and concentration of electrolytes in the tissues of rats and guinea pigs]. Farmakol.Toksikol. 1977;40(1):61-66. View abstract.
- Olziikhutag, A. [Comparative study of the effect of hippophae and sunflower oil on patients with coronary arteriosclerosis]. Kardiologiia. 1969;9(4):78-82. View abstract.
- Padmavathi, B., Upreti, M., Singh, V., Rao, A. R., Singh, R. P., and Rath, P. C. Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor. Nutr.Cancer 2005;51(1):59-67. View abstract.
- Padwad, Y., Ganju, L., Jain, M., Chanda, S., Karan, D., Kumar, Banerjee P., and Chand, Sawhney R. Effect of leaf extract of Seabuckthorn on lipopolysaccharide induced inflammatory response in murine macrophages. Int.Immunopharmacol. 2006;6(1):46-52. View abstract.
- Pang, X., Zhao, J., Zhang, W., Zhuang, X., Wang, J., Xu, R., Xu, Z., and Qu, W. Antihypertensive effect of total flavones extracted from seed residues of Hippophae rhamnoides L. in sucrose-fed rats. J.Ethnopharmacol. 5-8-2008;117(2):325-331. View abstract.
- Prakash, H., Bala, M., Ali, A., and Goel, H. C. Modification of gamma radiation induced response of peritoneal macrophages and splenocytes by Hipophae rhamnoides (RH-3) in mice. Journal of Pharmacy and Pharmacology (England) 2005;57:1065-1072.
- Raghavan AK, Raghavan SK, Khanum F, Shivanna N, and Singh BA. Effect of sea buckthorn leaves based herbal formulation on hexachlorocyclohexane--induced oxidative stress in rats. Journal of Dietary Supplements 2008;5(1):33-46.
- Saggu, S. and Kumar, R. Possible mechanism of adaptogenic activity of seabuckthorn (Hippophae rhamnoides) during exposure to cold, hypoxia and restraint (C-H-R) stress induced hypothermia and post stress recovery in rats. Food Chem.Toxicol. 2007;45(12):2426-2433. View abstract.
- Saggu, S., Divekar, H. M., Gupta, V., Sawhney, R. C., Banerjee, P. K., and Kumar, R. Adaptogenic and safety evaluation of seabuckthorn (Hippophae rhamnoides) leaf extract: a dose dependent study. Food Chem Toxicol 2007;45(4):609-617. View abstract.
- Seven, B., Varoglu, E., Aktas, O., Sahin, A., Gumustekin, K., Dane, S., and Suleyman, H. Hippophae rhamnoides L. and dexpanthenol-bepanthene on blood flow after experimental skin burns in rats using 133Xe clearance technique. Hell.J.Nucl.Med. 2009;12(1):55-58. View abstract.
- Sharma, U. K., Sharma, K., Sharma, N., Sharma, A., Singh, H. P., and Sinha, A. K. Microwave-assisted efficient extraction of different parts of Hippophae rhamnoides for the comparative evaluation of antioxidant activity and quantification of its phenolic constituents by reverse-phase high-performance liquid chromatography (RP-HPLC). J.Agric.Food Chem. 1-23-2008;56(2):374-379. View abstract.
- Suomela, J. P., Ahotupa, M., Yang, B., Vasankari, T., and Kallio, H. Absorption of flavonols derived from sea buckthorn (Hippophae rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. J Agric Food Chem 9-20-2006;54(19):7364-7369. View abstract.
- Thumm, E. J., Stoss, M., Bayerl, C., and Schurholz, T. H. Randomized trial to study efficacy of a 20% and 10% Hippophae rhamnoides containing creme used by patients with mild to intermediate atopic dermatitis. Aktuelle Dermatologie 2000;26(8-9):285-290.
- Tsimmerman, IaS and Mikhailovskaia, L. V. [Effect of sea buckthorn oil on various pathophysiologic mechanisms and the course of peptic ulcer]. Klin.Med.(Mosk) 1987;65(2):77-82. View abstract.
- Vijayaraghavan, R., Gautam, A., Kumar, O., Pant, S. C., Sharma, M., Singh, S., Kumar, H. T., Singh, A. K., Nivsarkar, M., Kaushik, M. P., Sawhney, R. C., Chaurasia, O. P., and Prasad, G. B. Protective effect of ethanolic and water extracts of sea buckthorn (Hippophae rhamnoides L.) against the toxic effects of mustard gas. Indian J Exp Biol 2006;44(10):821-831. View abstract.
- Vlasov, V. V. [Hippophae oil in the treatment of superficial skin burns]. Vestn.Dermatol Venerol. 1970;44(6):69-72. View abstract.
- Wang MH, Zhu F Lu M et al. Effects of total flavones of Hippopphae Rhamnoides L on renal function in patients with hypertension. China Science. 2005;5(6):447-448.
- Wang, Z. Y., Luo, X. L., and He, C. P. [Management of burn wounds with Hippophae rhamnoides oil]. Nan.Fang Yi.Ke.Da Xue.Xue.Bao. 2006;26(1):124-125. View abstract.
- Xing, J. F., Hou, J. Y., Dong, Y. L., and Wang, B. W. Effects on gastric secretion and anti-gastric ulcer action of sea buckthorn pulp oil in rats. Journal of China Pharmacy (China) 2003;14:461-463.
- Xing, J., Yang, B., Dong, Y., Wang, B., Wang, J., and Kallio, H. P. Effects of sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats. Fitoterapia 2002;73(7-8):644-650. View abstract.
- Xu WH, Chen J Deng ZT. Comparison between the total flavones of Hippopphae Rhamnoides L (TFH) and captopril on anti-hypertensive effects. China General Medicine. 2001;1(12):903-904.
- Xu, X., Xie, B., Pan, S., Liu, L., Wang, Y., and Chen, C. Effects of sea buckthorn procyanidins on healing of acetic acid-induced lesions in the rat stomach. Asia Pac.J.Clin.Nutr. 2007;16 Suppl 1:234-238. View abstract.
- Yang, B., Kalimo, K. O., Mattila, L. M., Kallio, S. E., Katajisto, J. K., Peltola, O. J., and Kallio, H. P. Effects of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on atopic dermatitis. J Nutr.Biochem. 1999;10(11):622-630. View abstract.
- Yang, B., Kalimo, K. O., Tahvonen, R. L., Mattila, L. M., Katajisto, J. K., and Kallio, H. P. Effect of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis. J Nutr.Biochem. 2000;11(6):338-340. View abstract.
- Zhang XJ, Zhang MS Wang JL et al. Effects of total flavones of Hippopphae Rhamnoides L (TFH) on pituitary gland. 2001:32(4):547. Szechuan University Medicine. 2001;32(4):547.
- Zhang, M. S. [A control trial of flavonoids of Hippophae rhamnoides L. in treating ischemic heart disease]. Zhonghua Xin.Xue.Guan.Bing.Za Zhi. 1987;15(2):97-99. View abstract.
- Zhang, W., Zhao, J., Wang, J., Pang, X., Zhuang, X., Zhu, X., and Qu, W. Hypoglycemic effect of aqueous extract of seabuckthorn (Hippophae rhamnoides L.) seed residues in streptozotocin-induced diabetic rats. Phytother.Res. 2010;24(2):228-232. View abstract.
- Zhang, X. Zhang M. Gao Z. Wang J. and Wang Z. Effect of total flavones of Hippophae rhamnoides L. on sympathetic activity in hypertension. Hua Xi.Yi.Ke.Da.Xue.Xue.Bao 2001;32(4):547-550.
- Zhang, X., Zhang, M., Gao, Z., Wang, J., and Wang, Z. [Effect of total flavones of Hippophae rhamnoides L. on sympathetic activity in hypertension]. Hua Xi.Yi.Ke.Da.Xue.Xue.Bao. 2001;32(4):547-550. View abstract.
- Zhu F, Hu CY Huang P et al. Effects of total flavones of Hippopphae Rhamnoides L. on artherial hypertension. China New Drug and Clinic 2004;23(8):501-503.
- Zhu, F., Zhang, M. S., and Wang, J. L. Inhibitory effect of total flavones of Hippophae rhamnoides L on angiotensin converting enzyme from rabbit. Chinese Journal of Clinical Pharmacy (China) 2000;9:95-98.
- Amosova EN, Zueva EP, Razina TG, et al. [The search for new anti-ulcer agents from plants in Siberia and the Far East]. Eksp Klin Farmakol 1998;61:31-5. View abstract.
- Changshun L, Xinming C, Fenrong W, et al. [Clinical observation on reflux esophagitis treated with seabuckthorn seed oil]. Hippophae 1996;9:40-1.
- Cheng TJ, Pu JK, Wu LW, et al. [A preliminary study on hepato-protective action of seed oil of Hippophae rhamnoides L. (HR) and mechanism of the action]. Chung Kuo Chung Yao Tsa Chih 1994;19:367-70, 384. View abstract.
- Cheng TJ. [Protective action of seed oil of Hippophae rhamnoides L. (HR) against experimental liver injury in mice]. Chung Hua Yu Fang I Hsueh Tsa Chih 1992;26:227-9. View abstract.
- Gao ZL, Gu XH, Cheng FT, Jiang FH. Effect of sea buckthorn on liver fibrosis: a clinical study. World J Gastroenterol 2003;9:1615-17. View abstract.
- Gengquan Q, Xiang Q. [A clinical report on the therapeutics of seabuckthorn oil softgels on peptic ulcer in 30 cases]. Hippophae 1997;10:39-41.
- Goldberg LD, Crysler C. A single center, pilot, double-blinded, randomized, comparative, prospective clinical study to evaluate improvements in the structure and function of facial skin with tazarotene 0.1% cream alone and in combination with GliSODin Skin Nutrients Advanced Anti-Aging Formula. Clin Cosmet Investig Dermatol. 2014;7:139-44. View abstract.
- Grad SC, Muresan I, Dumitrascu DL. Generalized yellow skin caused by high intake of sea buckthorn. Forsch Komplementmed. 2012;19(3):153-6. View abstract.
- Gutzeit D, Baleanu G, Winterhalter P, Jerz G. Vitamin C content in sea buckthorn berries (Hippophaë rhamnoides L. ssp. rhamnoides) and related products: a kinetic study on storage stability and the determination of processing effects. J Food Sci 2008;73:C615-20. View abstract.
- Ianev E, Radev S, Balutsov M, et al. [The effect of an extract of sea buckthorn (Hippophae rhamnoides L.) on the healing of experimental skin wounds in rats]. Khirurgiia (Sofiia) 1995;48:30-3. View abstract.
- Johansson AK, Korte H, Yang B, et al. Sea buckthorn berry oil inhibits platelet aggregation. J Nutr Biochem 2000;11:491-5.. View abstract.
- Agrawala, P. K. and Adhikari, J. S. Modulation of radiation-induced cytotoxicity in U 87 cells by RH-3 (a preparation of Hippophae rhamnoides). Indian J.Med.Res. 2009;130(5):542-549. View abstract.
- Aitzetmuller, K. and Xin, Y. [Sea buckthorn and sea buckthorn oils--recent developments in China and central Asia]. Nahrung 1999;43(4):228-232. View abstract.
- Backhouse, N., Rosales, L., Apablaza, C., Goity, L., Erazo, S., Negrete, R., Theodoluz, C., Rodriguez, J., and Delporte, C. Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. J.Ethnopharmacol. 3-5-2008;116(2):263-269. View abstract.
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