JEQUIRITY

OTHER NAME(S):

Abro, Abrus precatorius, Bead Vine, Black-Eyed Susan, Buddhist Rosary Bead, Chanothi, Chashami -Khurosa, Chunhali, Crab's Eye, Gaunchi, Ghunchi, Glycine Abrus, Grain D'Église, Gumchi, Gunchi, Gundumani, Gunja, Guruginia, Gurugunii, Haricot Paternoster, Herbe de Diable, Herbe du Diable, Indian Bead, Jequirity Bean, Jequirity Seed, Koonch, Kunch, Kundumani, Kunni, Liane Réglisse, Love Bean, Lucky Bean, Mulati, Ojo De Pajaro, Pater Noster, Pois Rouge, Prayer Beads, Prayer Head, Precatory Bean, Rati, Rati Gedi, Regaliz Americano, Réglisse Marron, Rosary Pea, Saga, Seminole Bead, Shangir, Soldat, Weather Plant, Weglis, Xian Si Zi.<br/><br/>

Overview

Overview Information

Jequirity is a climbing plant. The roots, leaves, and beans have been used as medicine.

Despite serious safety concerns, some people take jequirity by mouth for asthma, constipation, liver disease, infections, and other conditions. Some women use jequirity bean to speed up labor, cause an abortion, or prevent pregnancy. But there is no good scientific evidence that jequirity works to treat any of these or other conditions.

How does it work?

The jequirity plant contains many chemicals. Some chemicals in the leaves and root may help with allergy symptoms, improve blood sugar levels, slow blood clotting, reduce swelling, and kill bacteria, tapeworms, or cancer cells. Jequirity bean contains abrin, which is toxic to cells in the body.

Uses

Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of jequirity for these uses.

Side Effects

Side Effects & Safety

Jequirity is LIKELY UNSAFE when taken by mouth. Jequirity contains a chemical called abrin. Abrin is a poison and can cause death, even at low doses. Symptoms of toxicity include stomach cramping, followed by vomiting and severe diarrhea that can become bloody. Other symptoms include seizures, weakness, a fast heart rate, and liver or kidney failure. Symptoms can happen within hours or appear up to several days later. Death can occur after 3-4 days of persistent stomach problems and other symptoms.

When seeds come in contact with the skin, they can cause swelling, irritation, and severe eye problems.

Special Precautions & Warnings:

While jequirity bean isn't safe for anyone to take, some people should be particularly careful to avoid use.

Pregnancy and breast-feeding: Jequirity is LIKELY UNSAFE when taken by mouth during pregnancy or breast-feeding. Jequirity contains a chemical called abrin, which is a poison. Also, jequirity might cause labor to start. Avoid use.

Children: Jequirity is UNSAFE in children. Children are attracted to the bright colors of the seed, which is unfortunate since children are particularly sensitive to the toxic effects of jequirity bean. Children can die after swallowing just one seed. If exposure to jequirity bean is suspected, get immediate medical assistance.

Bleeding disorder; Jequirity might slow blood clotting. In theory, this might make bleeding disorders worse.

Diabetes: Jequirity might lower blood sugar. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use jequirity.

Surgery: Jequirity might slow blood clotting or lower blood sugar. In theory, jequirity might increase the risk of bleeding and interfere with blood sugar control during and after surgical procedures. Stop using jequirity at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

We currently have no information for JEQUIRITY Interactions.

Dosing

Dosing

The appropriate dose of jequirity depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for jequirity. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

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  • Adelowotan O, Aibinu I, Adenipekun E, Odugbemi T. The in-vitro antimicrobial activity of Abrus precatorius (L) fabaceae extract on some clinical pathogens. Niger Postgrad Med J 2008;15(1):32-37. View abstract.
  • Agarwal SS, Ghatak N, Arora RB, Bhardwaj MM. Antifertility activity of the roots of Abrus precatorius, Linn. Pharma Res Comm 1970;2(2):159-163.
  • Andrews JA. Jequirity Ophthalmia. Trans Am Ophthalmol Soc 1884;3:679-685. View abstract.
  • Bhutia SK, Mallick SK, Maiti S, Maiti TK. Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model. Chem Biol Interact 2008;174(1):11-18. View abstract.
  • Bhutia SK, Mallick SK, Maiti S, Maiti TK. Inhibitory effect of Abrus abrin-derived peptide fraction against Dalton's lymphoma ascites model. Phytomedicine 2009;16(4):377-385. View abstract.
  • Bhutia SK, Mallick SK, Maiti S, Mishra D, Maiti TK. Abrus abrin derived peptides induce apoptosis by targeting mitochondria in HeLa cells. Cell Biol Int 2009;33(7):720-727. View abstract.
  • Bhutia SK, Mallick SK, Maiti TK. In vitro immunostimulatory properties of Abrus lectins derived peptides in tumor bearing mice. Phytomedicine 2009;16(8):776-782. View abstract.
  • Bhutia SK, Mallick SK, Stevens SM, et al. Induction of mitochondria-dependent apoptosis by Abrus agglutinin derived peptides in human cervical cancer cell. Toxicol In Vitro 2008;22(2):344-351. View abstract.
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  • Nwanjo HU. Hypoglycemic and hypolipidemic effects of aqueous extracts of Abrus precatorius Linn seeds in streptozotocin-induced diabetic Wistar rats. J Herbs Spice Med Plants 2008;14(1-2):68-76.
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  • Patil MM, Patil SV, Akki AS, Lakhkar B, Badiger S. An arrow poison (Abrus precatorius) causing fatal poisoning in a child. J Clin Diagn Res 2016;10(3):SD03-4. View abstract.
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  • Ramnath V, Rekha PS, Kuttan G, Kuttan R. Regulation of Caspase-3 and Bcl-2 Expression in Dalton's Lymphoma Ascites Cells by Abrin. Evid Based Complement Alternat Med 2009;6(2):233-238. View abstract.
  • Rao MV. Antifertility effects of alcoholic seed extract of Abrus precatorius Linn. in male albino rats. Acta Eur Fertil 1987;18(3):217-220. View abstract.
  • Sahni V, Agarwal SK, Singh NP, Sikdar S. Acute demyelinating encephalitis after jequirity pea ingestion (Abrus precatorius). Clin Toxicol (Phila) 2007;45(1):77-79. View abstract.
  • Sahoo R, Hamide A, Amalnath SD, Narayana BS. Acute demyelinating encephalitis due to Abrus precatorius poisoning--complete recovery after steroid therapy. Clin Toxicol (Phila) 2008;46(10):1071-1073. View abstract.
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  • Somerset EJ. SELF INFLICTED CONJUNCTIVITIS: An account of cases produced by the jequirity and castor oil seeds. Br J Ophthalmol 1945;29(4):196-204. View abstract.
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  • Tripathi S, Ghosh D, Maiti TK. Immunostimulatory role of tryptic digest of Abrus agglutinin. Immunopharmacol Immunotoxicol 2004;26(3):411-424. View abstract.
  • Tripathi S, Maiti TK. Immunomodulatory role of native and heat denatured agglutinin from Abrus precatorius. Int J Biochem Cell Biol 2005;37(2):451-462. View abstract.
  • Umamahesh B, Veeresham C. Antihyperglycemic and insulin secretagogue activities of Abrus precatorius leaf extract. Pharmacognosy Res 2016;8(4):303-8. View abstract.
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  • Wu JH, Wu AM, Yang Z, et al. Recognition intensities of submolecular structures, mammalian glyco-structural units, ligand cluster and polyvalency in abrin-a-carbohydrate interactions. Biochimie 2010;92(2):147-156. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.