Overview
Jequirity is poisonous. Despite serious safety concerns, some people take jequirity by mouth for asthma, constipation, liver disease, and other conditions. But there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness ?
Insufficient Evidence for
- Quickening labor.
- Causing an abortion.
- Preventing pregnancy.
- Pain in terminally ill patients.
- Eyeinflammation.
- Asthma.
- Bronchial tube swelling.
- Fever.
- Hepatitis.
- Malaria.
- Seizures.
- Snakebites.
- Sore throat.
- Stomach pain.
- Tapeworms.
- Coughs.
- Common cold.
- Flu.
- Insect bites.
- Gonorrhea.
- Other conditions.
Side Effects
When seeds come in contact with the skin, they can cause swelling, irritation, and severe eye problems.
Special Precautions and Warnings
When seeds come in contact with the skin, they can cause swelling, irritation, and severe eye problems. While jequirity bean isn't safe for anyone to take, some people should be particularly careful to avoid use.
Pregnancy and breast-feeding: Jequirity is LIKELY UNSAFE when taken by mouth during pregnancy or breast-feeding. Jequirity contains a chemical called abrin, which is a poison. Also, jequirity might cause labor to start. Avoid use.
Children: Jequirity is UNSAFE in children. Children are attracted to the bright colors of the seed, which is unfortunate since children are particularly sensitive to the toxic effects of jequirity bean. Children can die after swallowing just one seed. If exposure to jequirity bean is suspected, get immediate medical assistance.
Bleeding disorder: Jequirity might slow blood clotting. In theory, this might make bleeding disorders worse.
Diabetes: Jequirity might lower blood sugar. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use jequirity.
Surgery: Jequirity might slow blood clotting or lower blood sugar. In theory, jequirity might increase the risk of bleeding and interfere with blood sugar control during and after surgical procedures. Stop using jequirity at least 2 weeks before a scheduled surgery.
Interactions ?
Medications for diabetes (Antidiabetes drugs) interacts with JEQUIRITY
Jequirity might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking jequirity along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with JEQUIRITY
Jequirity might slow blood clotting. Taking jequirity along with medications that also slow blood clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Moderate Interaction
Be cautious with this combination
Dosing
Adedapo AA, Omoloye OA, Ohore OG. Studies on the toxicity of an aqueous extract of the leaves of Abrus precatorius in rats. Onderstepoort J Vet Res. 2007;74(1):31-36. View abstract.
Adelowotan O, Aibinu I, Adenipekun E, Odugbemi T. The in-vitro antimicrobial activity of Abrus precatorius (L) fabaceae extract on some clinical pathogens. Niger Postgrad Med J 2008;15(1):32-37. View abstract.
Agarwal SS, Ghatak N, Arora RB, Bhardwaj MM. Antifertility activity of the roots of Abrus precatorius, Linn. Pharma Res Comm 1970;2(2):159-163.
Andrews JA. Jequirity Ophthalmia. Trans Am Ophthalmol Soc 1884;3:679-685. View abstract.
Bhutia SK, Mallick SK, Maiti S, Maiti TK. Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model. Chem Biol Interact 2008;174(1):11-18. View abstract.
Bhutia SK, Mallick SK, Maiti S, Maiti TK. Inhibitory effect of Abrus abrin-derived peptide fraction against Dalton's lymphoma ascites model. Phytomedicine 2009;16(4):377-385. View abstract.
Bhutia SK, Mallick SK, Maiti S, Mishra D, Maiti TK. Abrus abrin derived peptides induce apoptosis by targeting mitochondria in HeLa cells. Cell Biol Int 2009;33(7):720-727. View abstract.
Bhutia SK, Mallick SK, Maiti TK. In vitro immunostimulatory properties of Abrus lectins derived peptides in tumor bearing mice. Phytomedicine 2009;16(8):776-782. View abstract.
Bhutia SK, Mallick SK, Stevens SM, et al. Induction of mitochondria-dependent apoptosis by Abrus agglutinin derived peptides in human cervical cancer cell. Toxicol In Vitro 2008;22(2):344-351. View abstract.
Cheng J, Lu TH, Liu CL, Lin JY. A biophysical elucidation for less toxicity of agglutinin than abrin-a from the seeds of Abrus precatorius in consequence of crystal structure. J Biomed Sci 2010;17:34. View abstract.
Davies JH. Abrus precatorius (rosary pea). The most common lethal plant poison. J Fla Med Assoc 1978;65:188-91.
Dickers KJ, Bradberry SM, Rice P, Griffiths GD, Vale JA. Abrin poisoning. Toxicol Rev 2003;22(3):137-142. View abstract.
Dickers KJ, Bradberry SM, Rice P, Griffiths GD, Vale JA. Abrin poisoning. Toxicol Rev 2003;22(3):137-142. View abstract.
Fernando C. Poisoning due to Abrus precatorius (jequirity bean). Anaesthesia 2001;56:1178-80. View abstract.
Garaniya N, Bapodra A. Ethno botanical and Phytophrmacological potential of Abrus precatorius L.: A review. Asian Pac J Trop Biomed 2014;4(Suppl 1):S27-34. View abstract.
Georgewill OA, Georgewill UO. Anti-arthritic activity of abrus precatorious in albino rats. Internet J Laboratory Med 2010;4(1).
Ghosh D, Bhutia SK, Mallick SK, Banerjee I, Maiti, T. K. Stimulation of murine B and T lymphocytes by native and heat-denatured Abrus agglutinin. Immunobiology 2009;214(3):227-234. View abstract.
Ghosh D, Maiti TK. Effects of native and heat-denatured Abrus agglutinin on tumor-associated macrophages in Dalton's lymphoma mice. Immunobiology 2007;212(8):667-673. View abstract.
Ghosh D, Maiti TK. Immunomodulatory and anti-tumor activities of native and heat denatured Abrus agglutinin. Immunobiology 2007;212(7):589-599. View abstract.
Gul MZ, Ahmad F, Kondapi AK, Qureshi IA, Ghazi IA. Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts--an in vitro study. BMC Complement Altern Med 2013;13:53. View abstract.
Huang J, Zhang W, Li X, et al. Acute abrin poisoning treated with continuous renal replacement therapy and hemoperfusion successfully: A case report. Medicine (Baltimore). 2017;96(27):e7423. View abstract.
Jang DH, Hoffman RS, Nelson LS. Attempted suicide, by mail order: Abrus precatorius. J Med Toxicol 2010;6(4):427-430. View abstract.
Karthikeyan A, Amalnath SD. Abrus precatorius poisoning: a retrospective study of 112 patients. Indian J Crit Care Med 2017;21(4):224-5. View abstract.
Kuo SC, Chen SC, Chen LH, et al. Potent antiplatelet, anti-inflammatory and antiallergic isoflavanquinones from the roots of Abrus precatorius. Planta Med 1995;61:307-12. View abstract.
Limmatvapirat C, Sirisopanaporn S, Kittakoop P. Antitubercular and antiplasmodial constituents of Abrus precatorius. Planta Med 2004;70(3):276-278. View abstract.
Lin JY, Lee TC, Tung TC. Isolation of antitumor proteins abrin-A and abrin-B from Abrus precatorius. Int J Pept Protein Res 1978;12(5):311-317. View abstract.
Molgaard P, Nielsen SB, Rasmussen DE, et al. Anthelmintic screening of Zimbabwean plants traditionally used against schistosomiasis. J Ethnopharmacol 2001;74(3):257-264. View abstract.
Niyogi SK. Deadly crab's eye: Abrus precatorius poisoning. N Engl J Med 1969;281:51-2.
Niyogi SK. The toxicology of Abrus precatorius linnaeus. J Forensic Sci 1970;15:529-36.
Nwanjo HU. Hypoglycemic and hypolipidemic effects of aqueous extracts of Abrus precatorius Linn seeds in streptozotocin-induced diabetic Wistar rats. J Herbs Spice Med Plants 2008;14(1-2):68-76.
Okoko II, Osinubi AA, Olabiyi OO, et al. Antiovulatory and anti-implantation potential of the methanolic extract of seeds of Abrus precatorius in the rat. Endocr Pract 2010;16(4):554-560. View abstract.
Patil MM, Patil SV, Akki AS, Lakhkar B, Badiger S. An arrow poison (Abrus precatorius) causing fatal poisoning in a child. J Clin Diagn Res 2016;10(3):SD03-4. View abstract.
Pillay VV, Bhagyanathan PV, Krishnaprasad R, Rajesh RR, Vishnupriya N. Poisoning due to white seed variety of Abrus precatorius. J Assoc Physicians India 2005;53:317-319. View abstract.
Ramnath V, Kuttan G, Kuttan R. Effect of abrin on cell-mediated immune responses in mice. Immunopharmacol Immunotoxicol 2006;28(2):259-268. View abstract.
Ramnath V, Rekha PS, Kuttan G, Kuttan R. Regulation of Caspase-3 and Bcl-2 Expression in Dalton's Lymphoma Ascites Cells by Abrin. Evid Based Complement Alternat Med 2009;6(2):233-238. View abstract.
Rao MV. Antifertility effects of alcoholic seed extract of Abrus precatorius Linn. in male albino rats. Acta Eur Fertil 1987;18(3):217-220. View abstract.
Sahni V, Agarwal SK, Singh NP, Sikdar S. Acute demyelinating encephalitis after jequirity pea ingestion (Abrus precatorius). Clin Toxicol (Phila) 2007;45(1):77-79. View abstract.
Sahoo R, Hamide A, Amalnath SD, Narayana BS. Acute demyelinating encephalitis due to Abrus precatorius poisoning--complete recovery after steroid therapy. Clin Toxicol (Phila) 2008;46(10):1071-1073. View abstract.
Sinha R. Post-testicular antifertility effects of Abrus precatorius seed extract in albino rats. J Ethnopharmacol 1990;28(2):173-181. View abstract.
Sinha S, Mathur RS. Effect of steroidal fraction of seeds of Abrus precatorius Linn. on rat testis. Indian J Exp Biol 1990;28(8):752-756. View abstract.
Somerset EJ. SELF INFLICTED CONJUNCTIVITIS: An account of cases produced by the jequirity and castor oil seeds. Br J Ophthalmol 1945;29(4):196-204. View abstract.
Subrahmanyan D, Mathew J, Raj M. An unusual manifestation of Abrus precatorius poisoning: a report of two cases. Clin Toxicol (Phila) 2008;46(2):173-175. View abstract.
Sullivan G, Chavez PI. Mexican good-luck charm potentially dangerous. Vet Hum Toxicol 1981;23:259-60.
Taur DJ, Patil RY. Mast cell stabilizing and antiallergic activity of Abrus precatorius in the management of asthma. Asian Pac J Trop Med 2011;4(1):46-9. View abstract.
Tripathi S, Ghosh D, Maiti TK. Immunostimulatory role of tryptic digest of Abrus agglutinin. Immunopharmacol Immunotoxicol 2004;26(3):411-424. View abstract.
Tripathi S, Maiti TK. Immunomodulatory role of native and heat denatured agglutinin from Abrus precatorius. Int J Biochem Cell Biol 2005;37(2):451-462. View abstract.
Umamahesh B, Veeresham C. Antihyperglycemic and insulin secretagogue activities of Abrus precatorius leaf extract. Pharmacognosy Res 2016;8(4):303-8. View abstract.
Wang JP, Hsu MF, Chang LC, et al. Inhibition of plasma extravasation by abruquinone A, a natural isoflavanquinone isolated from Abrus precatorius. Eur J Pharmacol 1995;273:73-81. View abstract.
Wu JH, Wu AM, Yang Z, et al. Recognition intensities of submolecular structures, mammalian glyco-structural units, ligand cluster and polyvalency in abrin-a-carbohydrate interactions. Biochimie 2010;92(2):147-156. View abstract.
No related vitamins found
You Might Also Like
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.