WHITE HOREHOUND: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

White horehound is a plant. The parts that grow above the ground are used to make medicine.

White horehound is used for digestion problems including diabetes, loss of appetite, indigestion, bloating, gas, diarrhea, constipation, and liver and gallbladder complaints. It is also used for lung and breathing problems including cough, whooping cough, asthma, tuberculosis, bronchitis, and swollen breathing passages.

Women use white horehound for painful menstrual periods.

People also use it for yellowed skin (jaundice), to kill parasitic worms, to cause sweating, and to increase urine production.

White horehound is sometimes applied to the skin for skin damage, ulcers, and wounds.

In manufacturing, the extracts of white horehound are used as flavoring in foods and beverages, and as expectorants in cough syrups and lozenges. Expectorants are ingredients that make it easier to cough up phlegm.

How does it work ?

The chemicals in white horehound can thin mucus secretions, reduce spasms in the stomach and intestines, and decrease swelling (inflammation).

View References

REFERENCES:

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Berrougui, H., Isabelle, M., Cherki, M., and Khalil, A. Marrubium vulgare extract inhibits human-LDL oxidation and enhances HDL-mediated cholesterol efflux in THP-1 macrophage. Life Sci 12-14-2006;80(2):105-112. View abstract.

Boudjelal, A., Henchiri, C., Siracusa, L., Sari, M., and Ruberto, G. Compositional analysis and in vivo anti-diabetic activity of wild Algerian Marrubium vulgare L. infusion. Fitoterapia 2012;83(2):286-292. View abstract.

De Jesus, R. A., Cechinel-Filho, V., Oliveira, A. E., and Schlemper, V. Analysis of the antinociceptive properties of marrubiin isolated from Marrubium vulgare. Phytomedicine 2000;7(2):111-115. View abstract.

El Bardai, S., Lyoussi, B., Wibo, M., and Morel, N. Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat. Clin Exp Hypertens. 2004;26(6):465-474. View abstract.

El Bardai, S., Lyoussi, B., Wibo, M., and Morel, N. Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat. Clin Exp Hypertens. 2001;23(4):329-343. View abstract.

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Henderson MS and McCrindle R. Premarrubiin. A diterpernoid from marrubium vulgare L. J Chem Soc 1969;C:2014-2015.

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NICHOLAS, H. J. ISOLATION OF MARRUBIN, A STEROL, AND A SESQUITERPENE FROM MARRUBIUM VULGARE. J Pharm.Sci. 1964;53:895-899. View abstract.

Paula de, Oliveira A., Santin, J. R., Lemos, M., Klein Junior, L. C., Couto, A. G., Meyre da Silva, Bittencourt C., Filho, V. C., and Faloni de, Andrade S. Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae). J Pharm Pharmacol 2011;63(9):1230-1237. View abstract.

Perez-Cruz, F., Cortes, C., Atala, E., Bohle, P., Valenzuela, F., Olea-Azar, C., Speisky, H., Aspee, A., Lissi, E., Lopez-Alarcon, C., and Bridi, R. Use of pyrogallol red and pyranine as probes to evaluate antioxidant capacities towards hypochlorite. Molecules. 2013;18(2):1638-1652. View abstract.

Robles-Zepeda, R. E., Velazquez-Contreras, C. A., Garibay-Escobar, A., Galvez-Ruiz, J. C., and Ruiz-Bustos, E. Antimicrobial activity of Northwestern Mexican plants against Helicobacter pylori. J Med Food 2011;14(10):1280-1283. View abstract.

Zarai, Z., Kadri, A., Ben, Chobba, I, Ben, Mansour R., Bekir, A., Mejdoub, H., and Gharsallah, N. The in-vitro evaluation of antibacterial, antifungal and cytotoxic properties of Marrubium vulgare L. essential oil grown in Tunisia. Lipids Health Dis 2011;10:161. View abstract.

Amri B, Martino E, Vitulo F, et al. Marrubium vulgare L. leave extract: Phytochemical composition, antioxidant and wound healing properties. Molecules. 2017;22(11). pii: E1851. View abstract.

de Souza MM, De Jesus RA, Cechinel-Filho V, and et al. Analgesic profile of hydroalcoholic extract obtained from Marrubium vulgare. Phytomedicine. 1998 Apr;5(2):103-7. doi: 10.1016/S0944-7113(98)80005-6. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

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WHITE HOREHOUND - Uses, Side Effects, and More

Overview

How does it work ?

Uses & Effectiveness ?

Insufficient Evidence for

Side Effects

Special Precautions and Warnings

Interactions ?

Moderate Interaction

Medications for diabetes (Antidiabetes drugs) interacts with WHITE HOREHOUND

Medications for high blood pressure (Antihypertensive drugs) interacts with WHITE HOREHOUND

Dosing

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