Goldenseal (Hydrastis canadensis) is an herb in the buttercup family. The dried root is very commonly used in supplements in the US.

Goldenseal contains berberine, which might have effects against bacteria and fungi. Berberine also has properties that can lower blood pressure and help irregular heartbeat. But many of the important chemicals in goldenseal aren't absorbed well when taken by mouth. So, it's not clear if goldenseal has the same effects as berberine.

People use goldenseal for the common cold and other upper respiratory tract infections, hay fever, diarrhea, constipation, and many other conditions. But there is no good scientific evidence to support any of these uses.

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