Aceite de Hígado de Tiburón, Basking Shark Liver Oil, Cetorhinus maximus, Centrophorus squamosus, Deep Sea Shark Liver Oil, Dog Fish Liver Oil, Foie de Requin, Huile de Foie d'Aiguillat, Huile de Foie de Requin, Huile de Foie de Requin de Grands Fonds, Huile de Foie de Requin Pèlerin, Huile de Requin, Shark Liver, Shark Oil, Greenland Shark Liver Oil, Leafscale Gulper Shark Liver Oil, Piked Dogfish Liver Oil, Squalene, Squalus acanthias.


Overview Information

Shark liver oil is taken from the livers of different shark species. It is used to make medicine.

Shark liver oil is used along with usual cancer drugs to treat leukemia and other cancers; to prevent radiation illness from cancer X-ray therapy; to prevent the common cold, flu, and swine flu; and to boost the body's immune system.

People apply shark liver oil directly to the skin for skin conditions including skin cancer.

How does it work?

Shark liver oil contains chemicals that might have activity against cancer. Shark liver oil might also boost the immune system.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of shark liver oil for these uses.

Side Effects

Side Effects & Safety

Shark liver oil is POSSIBLY SAFE in adults when used short-term. Minor side effects related to the stomach and intestines have been reported. Liver injury has also been reported for one person taking shark liver oil. In high doses shark liver oil might increase cholesterol levels. Shark liver oil can cause pneumonia in people who accidentally breathe it into the lungs.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of shark liver oil during pregnancy and breast-feeding. Stay on the safe side and avoid use.

High cholesterol: People with high cholesterol should avoid taking shark liver oil or use it only in moderation. Shark liver oil might increase cholesterol levels when used in large amounts.



We currently have no information for SHARK LIVER OIL Interactions.



The appropriate dose of shark liver oil depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for shark liver oil. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Asnis DS, Saltzman HP, Melchert A. Shark oil pneumonia. An overlooked entity. Chest 1993;103:976-7. View abstract.
  • Deniau AL, Mosset P, Pédrono F, Mitre R, Le Bot D, Legrand AB. Multiple beneficial health effects of natural alkylglycerols from shark liver oil. Mar Drugs. 2010 Jul 19;8(7):2175-84. View abstract.
  • Hamadate N, Matsumoto Y, Seto K, Yamamoto T, Yamaguchi H, Nakagawa T, Yamamoto E, Fukagawa M, Yazawa K. Vascular effects and safety of supplementation with shark liver oil in middle-aged and elderly males. Exp Ther Med. 2015 Aug;10(2):641-646. Epub 2015 Jun 11. View abstract.
  • Hasle H, Rose C. [Shark liver oil (alkoxyglycerol) and cancer treatment]. Ugeskr Laeger 1991;153:343-6. View abstract.
  • Hichami A, Duroudier V, Leblais V, et al. Modulation of platelet-activating-factor production by incorporation of naturally occurring 1-O-alkylglycerols in phospholipids of human leukemic monocyte-like THP-1 cells. Eur J Biochem 1997;250:242-8. View abstract.
  • Kilincalp S, Deveci M, Basar O, Ekiz F, Coban S, Yuksel O. Shark liver oil: hidden dangers. Ann Hepatol. 2012 Sep-Oct;11(5):728-30. View abstract.
  • Lee JS, Im JG, Song KS, et al. Exogenous lipoid pneumonia: high-resolution CT findings. Eur Radiol 1999;9:287-91. View abstract.
  • Lee JY, Lee KS, Kim TS, et al. Squalene-induced extrinsic lipoid pneumonia: serial radiologic findings in nine patients. J Comput Assist Tomogr 1999;23:730-5. View abstract.
  • Loftsson T, Petersen DS, Le Goffic F, Olafsson JH. Unsaturated glycerol monoethers as novel skin penetration enhancers. Pharmazie 1997;52:463-5. View abstract.
  • Skopinska-Rozewska E, Krotkiewski M, Sommer E, et al. Inhibitory effect of shark liver oil on cutaneous angiogenesis induced in Balb/c mice by syngeneic sarcoma L-1, human urinary bladder and human kidney tumour cells. Oncol Rep 1999;6:1341-4. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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