Andrographis leaf and stem might work by stimulating the immune system. It might also prevent flu viruses from binding to cells in the body.
People commonly use andrographis for the common cold, osteoarthritis, infection of the throat and tonsils, and a type of bowel disease called ulcerative colitis. It is also used for many other conditions, but there is no good scientific evidence to support its other uses.
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
- Common cold. Taking andrographis by mouth, alone or as part of an herbal combination product, seems to improve cough and sore throat in some people with the common cold. It's not clear if andrographis helps to prevent colds.
- Osteoarthritis. Taking andrographis extract by mouth daily seems to reduce pain and stiffness in people with mild or moderate osteoarthritis in the knee.
- Infection of the throat and tonsils (tonsillopharyngitis). Taking andrographis by mouth daily works about as well as acetaminophen (Tylenol) to reduce fever and pain from tonsillitis.
- A type of inflammatory bowel disease (ulcerative colitis). Taking andrographis extract by mouth daily for 8 weeks reduces symptoms of ulcerative colitis about as well as the drug mesalamine.
Special Precautions and Warnings
Breastfeeding: There isn't enough reliable information to know if andrographis is safe to use when breast-feeding. Stay on the safe side and avoid use.
Children: Andrographis is possibly safe in children when taken by mouth, short-term. Andrographis has been used in combination with other herbs for up to one month in children 3-15 years of age.
"Auto-immune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Andrographis might cause the immune system to become more active, and this could increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using andrographis.
Bleeding conditions: Andrographis might slow blood clotting. This might increase the risk of bleeding or bruising in people with bleeding disorders.
Surgery: Andrographis might slow blood clotting and reduce blood pressure. It might cause extra bleeding or low blood pressure during and after surgery. Stop using andrographis at least 2 weeks before a scheduled surgery.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with ANDROGRAPHIS
Andrographis might slow blood clotting. Taking andrographis along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Medications for high blood pressure (Antihypertensive drugs) interacts with ANDROGRAPHIS
Andrographis seems to decrease blood pressure. Taking andrographis along with medications for high blood pressure might cause your blood pressure to go too low.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Medications that decrease the immune system (Immunosuppressants) interacts with ANDROGRAPHIS
Andrographis increases the immune system. By increasing the immune system, andrographis might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
Be cautious with this combination
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