Skip to content
My WebMD Sign In, Sign Up

Colorectal Cancer Health Center

Font Size
A
A
A

Produce May Protect Against Colon Cancer

By
WebMD Health News

Feb. 17, 2000 (New York) -- Spinach, broccoli, lettuce, tomatoes, oranges, and other fruits and vegetables rich in a carotenoid known as lutein may help stave off colon cancer, according to research in a recent issue of TheAmerican Journal of Clinical Nutrition.

Carotenoids are the yellow and orange pigments that give sweet potatoes, winter squash, carrots, apricots, papayas, and other fruits and vegetables their color. They are also found in broccoli and dark, leafy greens including spinach, kale, and collards. Carotenoids include alpha-carotene, beta-carotene, lycopene, lutein, zeaxanthin, and beta-cryptoxanthin.

In the study, researchers compared the diets of nearly 2,000 people with colon cancer with those of more than 2,400 colon cancer-free control subjects. Participants who reported eating the most lutein-rich foods were among the least likely to develop colon cancer, compared with those who reported eating the least lutein-rich foods. Lutein was most protective against developing colon cancer at a relatively young age (younger than 67) and developing tumors in the proximal, or central, part of the colon.

"The major dietary sources of lutein in subjects with colon cancer and in control subjects were spinach, broccoli, lettuce, tomatoes, oranges and orange juice, carrots, celery and greens, " the study's authors write. "These data suggest that incorporating these foods into the diet may help reduce the risk of developing colon cancer."

Exactly how lutein may reduce the risk of colon cancer is not fully understood, the authors point out. They speculate that this occurs because carotenoids are antioxidants, which may destroy the free radicals that are believed to accelerate aging and contribute to the formation of cancers and heart disease.

To arrive at its findings, the multicenter research team interviewed study participants about the foods that they consumed and how often they ate them during a two-year period.

The other carotenoids found in food did not protect against colon cancer, but lutein was shown to decrease the risk of developing the cancer, the research team reports.

"The benefit of all carotenoids has not been shown to consistently reduce risk of colon cancer. However, vegetables are the primary source of lutein, which has been shown to reduce risk of colon cancer," lead researcher Martha L. Slattery, PhD, MPH, of the University of Utah Medical School in Salt Lake City, tells WebMD.

"Many of these vegetable are also high in folate, another nutrient that may protect from colon cancer, [so] an easy tip is therefore to eat more vegetables, especially dark green vegetables or broccoli," she says, noting that oranges are also a good source of lutein.

Felicia Busch, RD, a spokesperson for the American Dietetic Association and a nutritionist in St. Paul, Minn., agrees.

Noting that lutein is a "powerfully potent food," Busch tells WebMD that "the take-home message is to eat more fruits and vegetables."

Today on WebMD

colorectal cancer slideshow
SLIDESHOW
what is your cancer risk
HEALTH CHECK
 
Colon Cancer Survival
VIDEO
Kemeny Chemo Side Effects
VIDEO
 

bread
ARTICLE
Colon vs Rectal Cancer
VIDEO
 
New Colorectal Treatments
VIDEO
can lack of sleep affect your immune system
FEATURE
 

Cancer Facts Quiz
QUIZ
Virtual Colonoscopy
VIDEO
 
Picture of the Colon
ANATOMY
Vitamin D
SLIDESHOW
 

WebMD Special Sections