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How is lamotrigine (Lamictal) used for bipolar disorder?

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Lamictal is approved by the FDA for the maintenance treatment of adults with bipolar disorder. It has been found to help delay bouts of depression, mania, hypomania (a milder form of mania), and mixed episodes in those being treated with standard therapy. It is especially effective in the prevention of bipolar depression. It was the first FDA-approved therapy since lithium for maintenance in bipolar disorder.

Lamictal is considered a mood-stabilizing anticonvulsant and is most commonly prescribed to prevent or control seizures in the treatment of epilepsy. Recent studies have shown it may possess antidepressant effects in bipolar disorder.

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment.  National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program.  MedicineNet: "Bipolar Disorder (Mania)."  WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Joseph Goldberg on November 7, 2017

SOURCES: WebMD Medical Reference: "Bipolar Disorder (Manic Depressive Disorder)." WebMD Assess Plus: Bipolar Disorder Assessment.  National Institute for Mental Health: "Step-BD Womens Studies."   Massachusetts General Hospital Bipolar Clinic & Research Program.  MedicineNet: "Bipolar Disorder (Mania)."  WebMD Medical Reference: "Effects of Untreated Depression." American Psychiatric Association: "Practice Guideline for the Treatment of Patients With Bipolar Disorder."






Reviewed by Joseph Goldberg on November 7, 2017

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What are the side effects of lamotrigine (Lamictal), used to treat bipolar disorder?

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