SPLEEN EXTRACT

OTHER NAME(S):

Bovine Spleen, Concentré de Rate, Extracto de Bazo, Extrait de Rate, Extrait de Rate Hydrolysé, Extrait Splénique, Extrait Splénique Prédigéré, Facteurs Spléniques, Hydrolyzed Spleen Extract, Predigested Spleen Extract, Rate Bovine, Rate Crue, Raw Spleen, Spleen, Spleen Concentrate, Spleen Factors, Spleen Peptides, Spleen Polypeptides, Splenopentin, Tuftsin.<br/><br/>

Overview

Overview Information

The spleen is an organ in people and animals that has three major jobs. First, it breaks down and removes old and damaged red blood cells. It also holds a reserve of blood that can be released into the circulatory system to meet a sudden demand, such as bleeding (hemorrhage). It also provides some white cells to fight infection. Spleen extract is produced from animal spleens and is used as medicine.

Spleen extract is given “as replacement therapy” in cases where the spleen has been surgically removed and or isn’t working properly.

People with low white blood cell counts, cancer, infections, or HIV-related infections take spleen extract to boost the immune system.

Spleen extract is also used for treating “autoimmune” diseases such as celiac disease, systemic lupus erythematosus (SLE), dermatitis herpetiformis, and rheumatoid arthritis.

Some people use spleen extract for a kidney disorder called glomerulonephritis, a blood disorder called thrombocytopenia, an intestinal disease called ulcerative colitis, and a blood vessel condition called vasculitis.

How does it work?

Spleen extract contains ingredients that are thought to stimulate the immune system.

Uses

Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of spleen extract for these uses.

Side Effects

Side Effects & Safety

It is not known if spleen extract is safe. There is some concern about contamination from sick or diseased animals. Until more is known, don't use products containing spleen extract.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of spleen extract during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for SPLEEN EXTRACT Interactions.

Dosing

Dosing

The appropriate dose of spleen extract depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for spleen extract. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

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  • Naim, J. O., Lanzafame, R. J., and van Oss, C. J. The effect of anti-tuftsin antibody on the phagocytosis of bacteria by human neutrophils. Immunol.Invest 1991;20(5-6):499-506. View abstract.
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  • Paulesu, L., Di Stefano, A., Luzzi, E., Bocci, V., Silvestri, S., and Nencioni, L. Effect of tuftsin and its retro-inverso analogue on the release of interferon (IFN-gamma) and tumor necrosis factor (TNF-alpha) by human leucocytes. Immunol.Lett. 1992;34(1):7-11. View abstract.
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  • Wiedermann, C. J., Niedermuhlbichler, M., Zilian, U., Geissler, D., Lindley, I., and Braunsteiner, H. Priming of normal human neutrophils by tachykinins: tuftsin-like inhibition of in vitro chemotaxis stimulated by formylpeptide or interleukin-8. Regul.Pept. 11-26-1991;36(3):359-368. View abstract.
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  • Zoli, G., Corazza, G. R., D'Amato, G., Bartoli, R., Baldoni, F., and Gasbarrini, G. Splenic autotransplantation after splenectomy: tuftsin activity correlates with residual splenic function. Br.J.Surg. 1994;81(5):716-718. View abstract.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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