TANNIC ACID: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Tannic acid is found in the nutgalls formed by insects on the twigs of certain oak trees. Purified tannic acid is sometimes used as medicine.

People use tannic acid for conditions such as cold sores, diaper rash, heat rash, and many others, but there is no good scientific evidence to support these uses.

In foods and beverages, tannic acid is used as a flavoring agent.

In manufacturing, tannic acid is used in ointments and suppositories; for tanning hides and manufacturing ink; and to kill dust mites on furniture.

How does it work ?

Tannic acid contains ingredients that have a protective effect on the skin.

View References

REFERENCES:

Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Osteoarthritis.Cartilage. 2012;20(11):1209-1216. View abstract.

Adamczyk B, Simon J, Kitunen V, Adamczyk S, Smolander A. Tannins and their complex interaction with different organic nitrogen compounds and enzymes: old paradigms versus recent advances. ChemistryOpen. 2017;6(5):610-614. View abstract.

Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Goh CL, Yoyong K. A comparison of topical tannic acid versus iontophoresis in the medical treatment of palmar hyperhidrosis. Singapore Med J. 1996;37(5):466-8. View abstract.

Jaramillo Á, Briones L, Andrews M, Arredondo M, Olivares M, Brito A, Pizarro F. Effect of phytic acid, tannic acid and pectin on fasting iron bioavailability both in the presence and absence of calcium. J Trace Elem Med Biol. 2015 Apr;30:112-7. View abstract.

Ko&lstrok;odziej M, Bebenek D, Konarska Z, Szajewska H. Gelatine tannate in the management of acute gastroenteritis in children: a randomised controlled trial. BMJ Open. 2018;8(5):e020205. View abstract.

McRae JM, Kennedy JA. Wine and grape tannin interactions with salivary proteins and their impact on astringency: a review of current research. Molecules. 2011;16(3):2348-64. View abstract.

Mennini M, Tolone C, Frassanito A, Midulla F, Cucchiara S, Aloi M. Gelatin tannate for acute childhood gastroenteritis: a randomized, single-blind controlled trial. Paediatr Drugs. 2017 Apr;19(2):131-137.View abstract.

Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Phytother Res. 2013;27(6):811-7. View abstract.

Smith DB, Jacobson BH. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. J Chiropr Med. 2011;10(3):147-56. View abstract.

Zhang J, Song Q, Han X, et al. Multi-targeted protection of acetaminophen-induced hepatotoxicity in mice by tannic acid. Int Immunopharmacol. 2017;47:95-105. View abstract.

Zhao W, Iyer V, Flores FP, Donhowe E, Kong F. Microencapsulation of tannic acid for oral administration to inhibit carbohydrate digestion in the gastrointestinal tract. Food Funct. 2013;4(6):899-905. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

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TANNIC ACID

Overview

How does it work ?

Uses & Effectiveness ?

Possibly Ineffective for

Insufficient Evidence for

Side Effects

Special Precautions and Warnings

Interactions ?

Major Interaction

Medications taken by mouth (Oral drugs) interacts with TANNIC ACID

Dosing

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