Achiote, Achiotillo, Annato, Annotta, Arbre Rouge à L&egrave;vre, Arnotta, Bija, Bixa orellana, Latkan, Lipstick Tree, Rocou, Rocouyer, Roucou.<br/><br/>


Overview Information

Annatto is a plant. The seed and leaf are used to make medicine.

People take annatto for diabetes, diarrhea, fevers, fluid retention, heartburn, malaria, and hepatitis. They also use it as an antioxidant and bowel cleanser.

Annatto is sometimes put directly on the affected area to treat burns and vaginal infections and to repel insects.

In foods, annatto is used as a coloring agent.

How does it work?

There isn't enough information to know how annatto works.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of annatto for these uses.

Side Effects

Side Effects & Safety

Annatto is LIKELY SAFE for most people when used in food amounts. It is not known if annatto is safe for use as a medicine.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking annatto if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Diabetes: Annatto might increase or decrease blood sugar levels. Monitor your blood sugar carefully if you have diabetes and use annatto as a medicine. The dose of your diabetes medication may need to be changed.

Surgery: Annatto might affect blood sugar levels. This has raised some concern that it might interfere with blood sugar control during and after surgery. Stop using annatto as a medicine at least 2 weeks before a scheduled surgery.



Moderate Interaction

Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with ANNATTO

    Annatto might increase blood sugar. Diabetes medications are used to lower blood sugar. By increasing blood sugar, annatto might decrease the effectiveness of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br><nb>Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



The appropriate dose of annatto depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for annatto. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.